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    Mapping a Mutation to its Gene: The "Fly Lab" as a Modern Research Experience
    Although genetics is an invaluable part of the undergraduate biology curriculum, it can be intimidating to students as well as instructors: Students must reduce their reliance on memorization and dive deep into quantitative analysis, and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    geneticsbioinformaticsdrosophilachi-square analysiscomplementation mappingmode of inheritancethree-point mapping
    Teaching Tools and Strategies
    2685

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    268

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    The Pipeline CURE: An Iterative Approach to Introduce All Students to Research Throughout a Biology Curriculum
    Participation in research provides personal and professional benefits for undergraduates. However, some students face institutional barriers that prevent their entry into research, particularly those from underrepresented groups who may stand to...

    Courses: Developmental BiologyDevelopmental Biology GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    epigeneticsundergraduate researchmendelian inheritanceSelf-EfficacyCUREsnature of scienceResiliencecurriculum strategiesreprogramming
    Lesson
    3454

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    3026

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    Using CRISPR-Cas9 to teach the fundamentals of molecular biology and experimental design
    One of the challenges of inquiry-based research experiences is balancing the instruction on skills and techniques with data generation and analysis. This is especially true in technique heavy disciplines such as molecular biology, where emphasis...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    experimental designcrisprmolecular technique
    Lesson
    2499

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    739

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    Using Zebrafish in a Developmental Biology Lab Course to Explore Interactions Between Development and the Environment
    Important learning outcomes for biology students include the ability to develop experiments as well as pull together concepts across their coursework. The field of developmental biology, especially environmental influences on development...

    Courses: Developmental BiologyDevelopmental Biology Science Process SkillsScience Process Skills

    toxicologymorphogenesisorganogenesis
    Lesson
    11753

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    1809

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    2

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    A virtual laboratory on cell division using a publicly-available image database
    Cell division is a key concept in cell biology. While there are many popular activities to teach students the stages of mitosis, most make use of simple schematics, cartoons, or textbook diagrams. Others engage students in acting out the stages,...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    image analysismicroscopymitosisCellular Processes
    Lesson
    3794

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    203

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    Isolation and Functional Analysis of a Pancreatic Enzyme in an Introductory Student Lab
    Structure and function are correlated at all levels of biology. This topic is typically addressed early in an undergraduate class in general or molecular biology before students have gained much skill or knowledge in molecular biology. However, an...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Introductory BiologyIntroductory Biology

    Protein StructureproteaseEnzymechemical bondscatalysissolubility
    Lesson
    1094

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    176

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    Fatty Acid Induction of Lipid Droplets in Cancer Cells
    There is a growing need for the development and communication of cell culture-based laboratory activities specifically designed for undergraduate students. This multi-week laboratory activity allows students to take part in the planning,...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    Course based undergraduate researchCell ImagingLive Cell Staining
    Lesson
    2505

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    622

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    Follow the Sulfur: Using Yeast Mutants to Study a Metabolic Pathway
    Students are frequently overwhelmed by the complexity of metabolic pathways and they think they have "learned" the pathway when they have memorized the individual reactions.  This laboratory lesson helps students to understand the...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    SelectionyeastMetabolismcysteinemediamethioninemutantPathwaysulfur
    Lesson
    4154

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    283

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    Analysis of Microbiomes Using Free Web-Based Tools in Online and In-Person Undergraduate Science Courses
    Our understanding of microbiomes, or the collection of microorganisms and their genes in a given environment, has been revolutionized by technological and computational advances. However, many undergraduate students do not get hands-on experiences...

    Courses: BioinformaticsBioinformatics EcologyEcology MicrobiologyMicrobiology

    microbiomeDNA SubwayCyVerseCourse based undergraduate researchQIIME2ranacapa
    Lesson
    1608

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    502

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    A Remote Introductory Biology Lab Using Backyard Birdwatching to Teach Data Analysis and Communication
    Asking questions, designing experiments, collecting data and interpreting those data, and communicating the results are some of the most important concepts an undergraduate biology lab can teach students. When the SARS-CoV2 pandemic forced our...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    ecologydata analysisdata collection
    Lesson
    6097

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    3893

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    CURE-all: Large Scale Implementation of Authentic DNA Barcoding Research into First-Year Biology Curriculum
    Growing calls in science education reform have emphasized wide-scale engagement of first-year undergraduate students in authentic research experiences; however, large course enrollments, inadequate student experience, limited resources and...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics EcologyEcology EvolutionEvolution GeneticsGenetics Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    phylogeneticsbioinformaticsBiodiversityprocess of sciencetaxonomyPCRDNADNA sequencegel electrophoresis
    Lesson
    3263

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    266

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    Application of a Bacterial Experimental Evolution System to Visualize and Teach Evolution in Action: A Course-Based Undergraduate Research Experience
    Concepts of evolution are typically taught through examples of extremely long timescales, which do not always resonate broadly. Here, we describe a course-based undergraduate research experience tailored for junior and senior undergraduate biology...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology EvolutionEvolution GeneticsGenetics MicrobiologyMicrobiology

    EvolutionmutationcompetitionNatural Selectionregulationstructure and functionreproductive fitnessgenotype to phenotypehomologs
    Essay
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    183

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    Strategies for developing a science communicator through authentic science writing assignments
    To prepare biology undergraduates to be able to read and evaluate the primary literature, it is beneficial to teach students how to write documents in the style of professional science style manuscripts. By breaking manuscripts into individual...

    Courses: Science Process SkillsScience Process Skills

    communicationPeer reviewscience writing
    Lesson
    2225

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    446

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    A Short Laboratory Module to Help Infuse Metacognition during an Introductory Course-based Research Experience
    A core competency identified in Vision and Change for undergraduate biology students is the Ability to Apply the Process of Science. Here, we describe a three-week laboratory module for students in an Introductory Cell and Molecular Biology...

    Courses: Science Process SkillsScience Process Skills

    metacognitiongene expressionScientific ProcessExperimenal DesignHypothesis Generationmodel organisms
    Lesson
    3491

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    491

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    How Many Squirrels Are in the Shrubs? A Lesson Plan for Comparing Methods for Population Estimation
    Estimating the population sizes of animals is a key skill for any student interested in ecology, conservation, or management. However, counting animals in natural habitats is difficult, and the many techniques that exist each rely on assumptions...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Professional Development and Career PlanningProfessional Development and Career Planning Science Process SkillsScience Process Skills

    population ecologywildlife managementpopulation estimationsciuridaeSquirrel-Net
    Lesson
    731

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    44

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    Breaking It Down: What Factors Control Microbial Decomposition Rates?
    Demonstrating and modeling changes in ecosystem processes in the laboratory classroom can be logistically difficult and expensive. This complexity often leaves little time for students to generate and test hypotheses. Yet, we must foster student...

    Courses: EcologyEcology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    data analysishypothesis testingdata visualizationdata managementMicrobial RespirationDecompostionAbiotic ConditionsResults Communication
    Lesson
    3133

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    541

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    A Student-Led Hearing on the Use of HeLa Cells in Research
    In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case study is for students to use guided questions to...

    Courses: Cell BiologyCell Biology Science Process SkillsScience Process Skills

    bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues
    Lesson
    3243

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    1149

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    CRISPR/Cas9 in yeast: a multi-week laboratory exercise for undergraduate students
    Providing undergraduate life-science students with a course-based research experience that utilizes cutting-edge technology, is tractable for students, and is manageable as an instructor is a challenge. Here, I describe a multi-week lesson plan...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics GeneticsGenetics MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    bioinformaticsPCRphenotypingCRISPR/Cas9gene editingcloningGenotypingRestriction enzyme
    Lesson
    2704

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    685

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    Teaching Biodiversity with Museum Specimens in an Inquiry-Based Lab
    In response to the growth of biology datasets and broad efforts to digitize data, an increasingly important skill for science students is the management and analysis of large datasets. We designed an inquiry-based lab module to introduce students...

    Courses: EcologyEcology EvolutionEvolution Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    data analysisnatural historyphylogenyBiodiversitymammalsAllen's RuleBergmann's Ruleecogeographymuseum research
    Lesson
    2750

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    538

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    Developing Data Literacy Skills and Connecting the Student Experience in the Classroom to the Community Through Biodiversity Projects
    Undergraduate education and long-term science literacy are enhanced by integrating data projects with public datasets and creating analysis summaries. Underutilized public datasets are often generated by community-based or citizen science projects...

    Courses: EcologyEcology Plant BiologyPlant Biology

    species richnessBiodiversitydisturbanceHabitat rangePopulation abundance