CourseSource: Resources

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A CURE-based approach to teaching genomics using mitochondrial genomes

There is an abundance (currently over 1016 DNA bases) of publicly available genetic sequence data and a dearth of trained genomicists to process and interpret it, necessitating more trained bioinformaticians with biological expertise. For...

Courses: Bioinformatics Genetics

proteinsMitochondrial GenomesNuclear GenomesrRNAtRNA

Teaching Tools and Strategies

4218

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428

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0

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"I Really Enjoy These Annotations:" Examining Primary Biological Literature Using Collaborative Annotation

Critically reading and evaluating claims made in the primary literature are vital skills for the future professional and personal lives of undergraduate students. However, the formal presentation of intricate content in primary research articles...

Courses: Developmental Biology Neurobiology

Stem cellsAdult neurogenesisCRISPR gene editing

Lesson

4762

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878

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Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy

Analyzing high-throughput DNA sequence data is a fundamental skill in modern biology. However, real and perceived barriers such as massive file sizes, substantial computational requirements, and lack of instructor background knowledge can...

Courses: Biochemistry and Molecular Biology Bioinformatics

bioinformaticsDNA sequenceRNAseqgene expression

Lesson

2546

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409

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An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching

Advances in Next Generation Sequencing (NGS) technology have led to development of many research methods for analyzing genomic data. Students studying biology at the undergraduate level must hone their skills at genomic analysis to participate in...

Courses: Bioinformatics Genetics Science Process Skills

Speciationgenome evolutiongenetic variation

Teaching Tools and Strategies

1031

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134

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An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes

To overcome many of the limitations of the paper laboratory notebook (PLN), we developed an electronic laboratory notebook (e-LN) for the Dynamic Genome course at the University of California. The Dynamic Genome course is an authentic research...

Courses: Science Process Skills

data collectionData annotationNotebook Skills

Teaching Tools and Strategies

2045

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326

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DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

Advances in high-throughput techniques have resulted in a rising demand for scientists with basic bioinformatics skills as well as workshops and curricula that teach students bioinformatics concepts. DNA Detective is a workshop we designed to...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Plant Biology

geneticsbioinformaticsDNAgenotypephenotypegenegene annotation

Lesson

3237

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651

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0

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A Hands-on Introduction to Hidden Markov Models

In this Lesson, we describe a classroom activity that demonstrates how a Hidden Markov Model (HMM) is applied to predict a eukaryotic gene, focusing on predicting one exon-intron boundary. This HMM lesson is part of the BIOL/CS 370...

Courses: Bioinformatics Genetics Science Process Skills

transcriptionexonintronsplicing

Lesson

7670

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368

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Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

Lesson

5874

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1152

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A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

Rapid advances in genomics and bioinformatics, the vast amount of data generated by next-generation sequencing, and the penetration of the ‘-omics’ into many areas of biology have created a need for students with hands-on experience with...

Courses: Biochemistry and Molecular Biology Bioinformatics Ecology Ecology Microbiology

epidemiologyresearchbioinformaticsgenomicspublic healthAntibiotic Resistant BacteriaSalmonellaDNA sequencingpathogenic bacteria

Lesson

7366

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1427

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0

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An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

Gene structure, transcription, translation, and alternative splicing are challenging concepts for many undergraduates studying biology. These topics are typically covered in a traditional lecture environment, but students often fail to master and...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics

bioinformaticsGenome BrowsergenomicsRNAseqsplicingComputer ModelGene Structure

Lesson

914

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211

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0

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Helping Students to Metacognitively Read Scientific Literature With Talking to the Text

Reading primary scientific literature enhances students’ understanding of material, increases their self-efficacy, and critical thinking skills. However, scientific articles often present multiple challenges to the students, the first among...

Courses: Introductory Biology Science Process Skills

scientific literaturereading comprehensionmetacognitionScience process skillsTalking to the TextDense Scientific Texts

Lesson

3275

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1270

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0

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A CRISPR/Cas Guide RNA Design In Silico Activity

CRISPR biotechnologies inspired by the Clustered Regularly Interspaced Short Palindromic Repeat RNA-guided nuclease adaptive bacterial immune system have revolutionized biology research and become ubiquitous tools for hypothesis and...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics

bioinformaticsgene expressiongenetic basis of diseaseCRISPR/Cas9genetic engineeringin silico

Lesson

1503

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360

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0

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How to Find a Gene: Retrieving Information From Gene Databases

A strong understanding of distinct gene components and the ability to retrieve relevant information from gene databases are necessary to answer a diverse set of biological questions. However, often there is a considerable gap between...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

NCBItranscriptiontranslationGene StructureGene databasesEnsembl

Lesson

1314

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100

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0

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Introducing Immunology Research Literature to Understand B-cell Receptor Gene Expression

Immunology is relevant to our everyday lives, driving a need for more engaging and inclusive undergraduate immunology education. One way to engage a diverse group of learners is by teaching them how to read and interpret the scientific literature....

Courses: Immunology Science Process Skills

recombinationantibodyV(D)J recombinationB-cell receptorlymphocyte receptor

Essay

3236

views

86

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A Multi-Institutional Alternative Assessment Faculty Learning Community: Supporting Teaching in Higher Education

Faculty learning communities (FLCs) provide opportunities for professional development for faculty, teaching staff, and educational developers in a collaborative and open environment. In this essay, we describe our experience organizing,...

Courses: Professional Development and Career Planning

professional developmentAlternative AssessmentFaculty Learning Community

Lesson

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635

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Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...

Courses: Biochemistry and Molecular Biology Bioinformatics Introductory Biology

BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

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965

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277

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Quantifying and Visualizing Campus Tree Phenology

Large enrollment courses present a challenge for instructors who want to engage students in authentic science practices that fit the recommendations of Vision & Change. Our lesson provides a meaningful science experience for undergraduates in...

Courses: Introductory Biology

ecologyBiodiversityphenologyplant biology

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792

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320

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Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics

Physics labs are moving increasingly to open-ended experiments where students develop experimental physics skills, rather than verify textbook physics concepts. This sequence of activities sets the stage for this new kind of lab early in the...

Courses: Introductory Physics: Calculus-Based

statisticsMeasurementlaboratoryuncertaintypendulumexperimental skills

Essay

1436

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113

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0

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Online Adaptation to "Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis"

We present here a simple and engaging experiment capitalizing on the universal need to rid our homes of fruit flies to teach experimental design and analysis. In an earlier paper, we described an experiment in which students learn the scientific...

Courses: Science Process Skills

data analysisexperimental designolfaction

Lesson

3956

views

273

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0

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Learning to Pipet Correctly by Pipetting Incorrectly?

Beginning undergraduate students in biology need basic laboratory, data analysis, and science process skills to pursue more complex questions in course-based undergraduate research experiences (CUREs). To this end, we designed an introductory...

Courses: Introductory Biology Science Process Skills

statisticslaboratorypipetting

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A CURE-based approach to teaching genomics using mitochondrial genomes

"I Really Enjoy These Annotations:" Examining Primary Biological Literature Using Collaborative Annotation

Tackling "Big Data" with Biology Undergrads: A Simple RNA-seq Data Analysis Tutorial Using Galaxy

An Introduction to Eukaryotic Genome Analysis in Non-model Species for Undergraduates: A tutorial from the Genome Consortium for Active Teaching

An Open Source, Collaborative Electronic Notebook for Undergraduate Laboratory Classes

DNA Detective: Genotype to Phenotype. A Bioinformatics Workshop for Middle School to College.

A Hands-on Introduction to Hidden Markov Models

Investigating Cell Signaling with Gene Expression Datasets

A CURE for Salmonella: A Laboratory Course in Pathogen Microbiology and Genomics

An undergraduate bioinformatics curriculum that teaches eukaryotic gene structure

Helping Students to Metacognitively Read Scientific Literature With Talking to the Text

A CRISPR/Cas Guide RNA Design In Silico Activity

How to Find a Gene: Retrieving Information From Gene Databases

Introducing Immunology Research Literature to Understand B-cell Receptor Gene Expression

A Multi-Institutional Alternative Assessment Faculty Learning Community: Supporting Teaching in Higher Education

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

Quantifying and Visualizing Campus Tree Phenology

Quantifying Uncertainty and Distinguishing Data Sets in Introductory Physics

Online Adaptation to "Gotcha! Which fly trap is the best? An introduction to experimental data collection and analysis"

Learning to Pipet Correctly by Pipetting Incorrectly?

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