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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

    Courses: BioinformaticsBioinformatics EcologyEcology EvolutionEvolution Science Process SkillsScience Process Skills

    modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning
    Lesson
    1419

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    200

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    Modeling Strep Throat Detection, Infection, and Spread Using an SIR Model and the Vensim Simulation Software
    The overarching goal of this lesson is to provide students with an opportunity to gain experience making and using biological models. Biological modeling can be used to investigate complex, real-world problems so that predictions can be made about...

    Courses: Cell BiologyCell Biology ImmunologyImmunology Introductory BiologyIntroductory Biology MicrobiologyMicrobiology

    infectious diseasebiological modelingSIR model
    Lesson
    1903

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    633

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    1

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Introductory BiologyIntroductory Biology

    BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix
    Lesson
    1926

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    215

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    A new approach to course-based research using a hermit crab-hydrozoan symbiosis
    There are few feasible models for marine-focused inquiry laboratory activities, a notable shortcoming for instructors seeking to engage their students in meaningful, course-based research experiences (CUREs). We describe a multi-week CURE that...

    Courses: EcologyEcology EvolutionEvolution Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    behaviorparasitismSymbiosismutualismcommensalism
    Lesson
    4894

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    2357

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    Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages
    The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that infect bacteria and are either virulent or...

    Courses: MicrobiologyMicrobiology

    bacteriophagesLysogenic cycleLysogenyLytic cycle
    Lesson
    3582

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    387

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    0

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and analysis. Here, we share a series of four...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Science Process SkillsScience Process Skills

    bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor
    Lesson
    3836

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    1265

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)
    Lesson
    2356

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    451

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    A Modeling Exercise in Sexual Selection using a Student-Created Bird Species
    Evolution-centered lessons at the undergraduate level can often be jargon-heavy, propagate misconceptions if taught ineffectively, and be uninteresting to students who may not see the relevancy of such concepts. This activity provides a fun and...

    Courses: EcologyEcology EvolutionEvolution Introductory BiologyIntroductory Biology

    Evolutionfitnesssexual selectionNatural Selectionintersexual selectionmate choice
    Lesson
    1438

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    286

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    Promoting Climate Change Literacy for Non-majors: Implementation of an atmospheric carbon dioxide modeling activity as an inquiry-based classroom activity
    Students who are directly involved in scientific activities develop a deeper understanding and appreciation of both scientific knowledge and the scientific process. This understanding is critically important in scientific areas like climate change...

    Courses: Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    modelingExcelquantitativeclimate changeEnvironmental Biologyatmospheric carbon dioxide
    Lesson
    1937

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    511

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    0

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    Students require a deep understanding of the central dogma before they can understand complex topics such as evolution and biochemical disorders. However, getting undergraduate biology students to apply higher-order thinking skills to the central...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    Protein Structurecomputational modelingcentral dogmaplant leaf structurePhenotype/Genotype
    Lesson
    3716

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    415

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    A Classroom Intervention to Reduce Confirmation Bias
    STEM students are often unable to recognize cognitive bias in their own disciplines, and simply describing cognitive bias to students has shown to be insufficient to improve critical thinking. However, habitual metacognitive techniques show...

    Courses: Science Process SkillsScience Process Skills

    biasprocess of sciencemetacognitionConfirmation BiasCognitive Bias
    Lesson
    2040

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    246

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    1

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    Discovering Prokaryotic Gene Regulation by Building and Investigating a Computational Model of the lac Operon
    The ability to construct and reason through a biological system is an important skill to develop in science education. This level of understanding forces students to recognize the interrelatedness of components within a biological process and...

    Courses: Introductory BiologyIntroductory Biology

    prokaryotesgene regulationLac Operoninducible operon
    Lesson
    1517

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    362

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    Taking the Hassle out of Hasselbalch
    Mention pH in a classroom and you can almost see the inner yawn on the faces of your students. The definition may even roll easily from their lips. However, despite multiple exposures to the relationship of pH and pKa throughout a typical...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Science Process SkillsScience Process Skills

    pHdrug uptakeHenderson-Hasslbalch equationmedical applicationspKa
    Lesson
    1199

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    334

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    A first lesson in mathematical modeling for biologists: Rocs
    Using a fictitious population of Rocs, a mythical species of giant raptor, students accomplish two broad objectives: 1) they undertake the process of building a first mathematical model of a population, and 2) they begin to develop their...

    Courses: EcologyEcology Introductory BiologyIntroductory Biology Science Process SkillsScience Process Skills

    population ecologypopulation modelingdiscrete generationpopulation management
    Lesson
    4632

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    626

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    Investigating Enzyme Structure and Function Through Model-Building and Peer Teaching in an Introductory Biology Course
    A foundational knowledge of the relationship between structure and function is critical to understanding how enzymes work. The seemingly invisible nature of these molecular interactions makes it challenging for undergraduate students to...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Introductory BiologyIntroductory Biology

    structure-functionEnzymeallosteric regulationcompetitive inhibitionfeedback inhibitionnoncompetitive inhibitionproductsubstrate
    Lesson
    1347

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    118

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    0

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    The Developmental Origins of Mythology: A Pandemic-Inspired Innovative Developmental Biology Laboratory Exercise
    From an experiential, hands-on perspective, the Developmental Biology Laboratory is easily amenable to a wide range of undergraduate-friendly experiments. Thus, pivoting to a virtual laboratory during the COVID-19 pandemic required significant...

    Courses: Developmental BiologyDevelopmental Biology

    gastrulationaxis formationlimb developmentchimeramidline
    Lesson
    1018

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    68

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    Understanding the Importance of Microtubules in Normal Cell Division: Chemotherapy Connection
    In introductory courses, students learn about microtubules as important structures but may not engage in a hands-on experience to localize microtubules themselves or to learn about their connection to cancer treatment. In this lesson, students...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology GeneticsGenetics

    cancerCell DivisionimmunofluorescenceMicrotubulesAntibodies
    Lesson
    1670

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    289

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    Authentic Ecological Inquiries Using BearCam Archives
    Learning through authentic scientific inquiries is essential for understanding the nature and process of science and for developing critical thinking and communication skills. It is logistically challenging, however, to offer experiences of...

    Courses: EcologyEcology Science Process SkillsScience Process Skills

    behaviorinterspecific interactionsPeer reviewauthentic inquiryintra-specific interactions
    Lesson
    2802

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    330

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    0

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    Discovering Cellular Respiration with Computational Modeling and Simulations
    Cellular respiration, a common topic among introductory and cellular biology curricula, is a complex biological process that exemplifies core biological concepts, including systems, pathways and transformation of energy, and structure and function...

    Courses: Introductory BiologyIntroductory Biology

    Cellular MechanismsCellular RespirationFermentation
    Lesson
    1248

    views

    145

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    0

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    Using Collaborative Projects to Promote Active Learning of Microbial Skin Diseases and Their Impact on Everyday Lives
    One of the most daunting aspects of introductory clinical microbiology is learning details about a vast number of different microbial diseases that can infect humans. Each of these diseases has different causative agents, diagnostic procedures,...

    Courses: MicrobiologyMicrobiology

    infectious diseasecollaborationpathogenesisTreatment of diseasesReal-life Microbiology