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    It's a Substrate... It's a Protein...No - It's an Enzyme! Teaching Using 3D Serine Protease Physical Modeling Activities to Confront Misconceptions.
    Reported misconceptions of enzyme-substrate interactions highlight the necessity for better, targeted instructional tools and assessments. A series of active learning activities with corresponding three-dimensional (3D) physical models were...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology

    Protein StructureEnzymes-Substrate InteractionsNoncovalent InteractionsGeometric ComplementaryElectronicsStereochemistrySerine Proteases
    Lesson
    941

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    274

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    Quantifying and Visualizing Campus Tree Phenology
    Large enrollment courses present a challenge for instructors who want to engage students in authentic science practices that fit the recommendations of Vision & Change. Our lesson provides a meaningful science experience for undergraduates in...

    Courses: Introductory BiologyIntroductory Biology

    ecologyBiodiversityphenologyplant biology
    Lesson
    1029

    views

    133

    downloads

    1

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    Exploring the March to Mars Using 3D Print Models
    With the increased availability of 3D printers and open databases containing 3D print files, academic institutions are giving more thought into how such technology can be used in the classroom to further student learning. One way that 3D print...

    Courses: Introductory BiologyIntroductory Biology MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    waterMarsmicroorganismsproperties of life
    Lesson
    2872

    views

    859

    downloads

    1

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    Fruit Fly Genetics in a Day: A Guided Exploration to Help Many Large Sections of Beginning Students Uncover the Secrets of Sex-linked Inheritance
    Moving beyond the basic concepts of autosomal Mendelian inheritance to sex-linkage can be difficult for introductory biology students. Although crosses with Drosophila fruit flies have long been a mainstay of genetics units that teach these...

    Courses: GeneticsGenetics

    Mendelian Geneticsfruit fly biologysex-linked inheritance
    Lesson
    1872

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    839

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    0

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    Exploration of the Human Genome by Investigation of Personalized SNPs
    Students often shy away from tedious bioinformatics approaches to exploring their genomes. However, in our expanding digital world these skills are some of the most relevant and valuable. To increase students' interest in their own genomes, I...

    Courses: BioinformaticsBioinformatics GeneticsGenetics Science Process SkillsScience Process Skills

    UCSC genome browsersingle nucleotide polymorphismGenome wide association studiesGenomic organization
    Teaching Tools and Strategies
    5312

    views

    133

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    0

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    Walkabout: An Easy to Use, Experiential Learning Activity for Applying Abstract Concepts to the Real-World
    Students can have difficulty recognizing examples of course concepts in the real-world. They particularly struggle with phenomena that are ambiguously defined, have mimics, or are hard to distinguish from other phenomena. Students can better...

    Courses: EcologyEcology Science Process SkillsScience Process Skills

    data gatheringgreen technologyobservations
    Lesson
    2902

    views

    429

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    0

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    Moths and Frogs and E. coli, Oh My!: Agent-based Modeling of Evolutionary Systems
    In evolution classrooms, introducing and reinforcing the idea of genetic drift and random selection can be challenging, as can be reinforcing appropriate mental models of evolution. Agent-based models offer students the opportunity to conduct a...

    Courses: BioinformaticsBioinformatics EcologyEcology EvolutionEvolution Science Process SkillsScience Process Skills

    modelingEvolutionecologyagent-based modelingGenetic Driftenvironmental scienceNatural Selectioncompetitive coevolutionsimulation modelingevolutionary reasoning
    Essay
    1284

    views

    218

    downloads

    2

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    Designing an Asynchronous, Self-Led Aquatic Ecology Field Trip
    Due to the COVID-19 pandemic and increasing need to teach students online, aquatic scientists are looking for ways to give students field experiences virtually. Asynchronous, self-led field trips are emerging as a solution. However, due to the...

    Courses: EcologyEcology

    observationecosystem structureexploration
    Lesson
    9147

    views

    490

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    0

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    Manuscript 101: A Data-Driven Writing Exercise for Beginning Scientists
    Learning to write a scientific manuscript is one of the most important and rewarding scientific training experiences, yet most young scientists only embark on this experience relatively late in graduate school after gathering sufficient data in...

    Courses: BioinformaticsBioinformatics Cell BiologyCell Biology Developmental BiologyDevelopmental Biology GeneticsGenetics MicrobiologyMicrobiology Science Process SkillsScience Process Skills

    geneticsanimaldevelopmentcompetitionbacterial
    Lesson
    3556

    views

    382

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    0

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    Using Open-Source Bioinformatics and Visualization Tools to Explore the Structure and Function of SARS-CoV-2 Spike Protein
    The relationship between protein structure and function is a foundational concept in undergraduate biochemistry. We find this theme is best presented with assignments that encourage exploration and analysis. Here, we share a series of four...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Science Process SkillsScience Process Skills

    bioinformaticsmolecular modelingCOVID19protein structure and functionUCSF ChimeraSARS-CoV-2 spike proteinACE2 receptor
    Lesson
    6335

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    1582

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    Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson
    There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology GeneticsGenetics Introductory BiologyIntroductory Biology

    bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq
    Lesson
    1872

    views

    633

    downloads

    1

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    Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses
    Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Introductory BiologyIntroductory Biology

    BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix
    Lesson
    873

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    126

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    0

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    BioMap Degree Plan: A project to guide students in exploring, defining, and building a plan to achieve career goals
    Traditional college students begin their academic journey with a variety of ideas about the careers they might ultimately pursue. Some students have always known what they want to do, some have ideas about possible careers, while others have never...

    Courses: Introductory BiologyIntroductory Biology Professional Development and Career PlanningProfessional Development and Career Planning

    Career ExplorationCo-curricularsDegree Planning
    Essay
    2038

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    195

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    Structuring Courses for Equity
    As instructors, we continually look for new ways to create equitable learning environments and support learning for all students in our courses. Recently, we have explored ways that we can increase structure to better support students. We have...

    Courses: Anatomy-PhysiologyAnatomy-Physiology BioinformaticsBioinformatics Cell BiologyCell Biology Developmental BiologyDevelopmental Biology EcologyEcology GeneticsGenetics Introductory BiologyIntroductory Biology MicrobiologyMicrobiology NeurobiologyNeurobiology Plant BiologyPlant Biology Science Process SkillsScience Process Skills

    Equitymetacognitioninclusivitycourse structure
    Teaching Tools and Strategies
    1512

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    297

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    0

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    SCIENCE/Fiction: Modular Template for Class Design
    We present a modular scaffold for designing an introductory seminar using speculative fiction and science papers to welcome university undergraduates to the biology major. A list of twelve possible topics is included, such as Memory, Parasites,...

    Courses: Anatomy-PhysiologyAnatomy-Physiology Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology EvolutionEvolution GeneticsGenetics Introductory BiologyIntroductory Biology NeurobiologyNeurobiology

    geneticscell biologyneurosciencesystems biologyScience Fiction
    Lesson
    1893

    views

    332

    downloads

    0

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    Vitamin C for Colds? Writing LETTERS to Synthesize and Communicate Results from Multiple Studies
    Interpreting experimental results is a key part of evidence-based reasoning. However, it is challenging for students to synthesize data from multiple sources to reach their own conclusions. As experimental design is increasingly emphasized in...

    Courses: Science Process SkillsScience Process Skills

    pre-healthphysiologyScience Communicationscientific literacyScientific Processconventional wisdomscientific methods
    Essay
    3211

    views

    80

    downloads

    0

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    A Multi-Institutional Alternative Assessment Faculty Learning Community: Supporting Teaching in Higher Education
    Faculty learning communities (FLCs) provide opportunities for professional development for faculty, teaching staff, and educational developers in a collaborative and open environment. In this essay, we describe our experience organizing,...

    Courses: Professional Development and Career PlanningProfessional Development and Career Planning

    professional developmentAlternative AssessmentFaculty Learning Community
    Lesson
    2631

    views

    304

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes could affect their behavior via...

    Courses: Cell BiologyCell Biology EcologyEcology EvolutionEvolution ImmunologyImmunology Introductory BiologyIntroductory Biology MicrobiologyMicrobiology

    dietanimal behaviorimmune systemmicrobiomeNervous systemgut-brain axisImmunoReachdysbiosisCoyoteCytokines
    Lesson
    4584

    views

    456

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    Does Organelle Shape Matter?: Exploring Patterns in Cell Shape and Structure with High-Throughput (HT) Imaging
    Organelle structure has been studied and visualized for decades; however, publicly available databases that use improved high-throughput microscopy of gene-edited cell lines have recently revolutionized the amount and quality of information now...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology BioinformaticsBioinformatics Cell BiologyCell Biology GeneticsGenetics Science Process SkillsScience Process Skills

    modelingcase studymicroscopystructureOrganellesHigh-throughput (HT)Endoplasmic Reticulum (ER)Fluorescent microscopyHuman Cell Biology
    Lesson
    3781

    views

    1256

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    Evaluating the Quick Fix: Weight Loss Drugs and Cellular Respiration
    One key to student success in introductory and cell biology courses is a foundational knowledge of cellular respiration. This is a content area in which students often harbor misconceptions that make cellular respiration particularly challenging...

    Courses: Biochemistry and Molecular BiologyBiochemistry and Molecular Biology Cell BiologyCell Biology Introductory BiologyIntroductory Biology

    data analysisCellular RespirationElectron Transport ChainEnergy transformationsMitochondriaOxidative phosphorylationWeight loss drugs24-dinitrophenol (DNP)