CourseSource: Resources

Lesson

2421

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258

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0

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The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Students have difficulty understanding synaptic integration in neural circuits, and how spatial and temporal summation combine in a target neuron to reach threshold. This Lesson uses small cups of water to represent excitatory postsynaptic...

Courses: Neurobiology

neuron physiologyspatial summationsynaptic integrationtemporal summationthreshold

Review

1808

views

114

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0

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Making Change Sustainable: Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) Meeting Review

The purpose of the meeting described in this review was to decide how best to ensure the sustainability of the Network for Integrating Bioinformatics into Life Science Education (NIBLSE; pronounced “nibbles”). Biology research today...

Courses: Bioinformatics

meetingsustainabilityfmnNIBLSEincubator

Lesson

2750

views

509

downloads

2

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A Fun Introductory Command Line Lesson: Next Generation Sequencing Quality Analysis with Emoji!

Radical innovations in DNA sequencing technology over the past decade have created an increased need for computational bioinformatics analyses in the 21st century STEM workforce. Recent evidence however demonstrates that there are significant...

Courses: Bioinformatics

bioinformaticsgenomicscodingJupyter notebookcommand lineCyVersescriptingnext generation sequencing analysis

Teaching Tools and Strategies

1084

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109

downloads

0

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Transitioning Two-Stage Exams to an Online Class

Students often find biology courses to be very difficult and isolating, particularly if they identify as part of a group that has been historically excluded from STEM. Some of this anxiety and isolation comes from high-stakes exams. We decided to...

Courses: Anatomy-Physiology

lower division STEMupper division STEM

Lesson

1109

views

537

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0

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Understanding Gastric Acid Secretion: An Active Learning Approach

The human digestive system is a diverse network of cells, tissues, and organs that is regulated by systemic (e.g., nervous and endocrine systems) and local factors (e.g., secretions, pH, and the microbiome). Given the volume of content and the...

Courses: Anatomy-Physiology

diseasesignal transductionAcid SecretionAutonomic Nervous SystemEndocrineGastric PhysiologyGPCRHistology of Gastric Pit

Essay

1362

views

123

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0

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Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix

In light of the COVID-19 pandemic, instructors have modified materials to transition to a remote learning platform. The challenge for science instructors has been to design lab exercises that incorporate both active and experiential learning. In...

Courses: Cell Biology Neurobiology

remote learningExtracellular matrixNeural extracellular matrixPerineuronal net

Lesson

6387

views

1601

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0

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Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

There is a growing need for integration of “Big Data” into undergraduate biology curricula. Transcriptomics is one venue to examine biology from an informatics perspective. RNA sequencing has largely replaced the use of microarrays for whole...

Courses: Biochemistry and Molecular Biology Bioinformatics Cell Biology Genetics Introductory Biology

bioinformaticscancertranscriptomicshigh-throughputData wranglingSingle cell RNA sequencingq

Lesson

1459

views

315

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0

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Investigating Gene Expression and Cell Specialization in Axolotl Embryos

The process of cell specialization is critical to the formation and function of tissues in animals and plants. Although gene expression, including the regulation of transcription, is taught in most introductory cell biology courses, the...

Courses: Biochemistry and Molecular Biology Cell Biology Developmental Biology Science Process Skills

developmenttranscriptiongene expressionmodel organismembryo

Lesson

1907

views

634

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1

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Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

Introductory bioinformatics exercises often walk students through the use of computational tools, but often provide little understanding of what a computational tool does "under the hood." A solid understanding of how a bioinformatics...

Courses: Biochemistry and Molecular Biology Bioinformatics Introductory Biology

BLASTmultiple sequence alignmentsequence similarityphylogramZika virusAlgorithmScoring Matrix

Lesson

4318

views

675

downloads

0

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A simple way for students to visualize cellular respiration: adapting the board game MousetrapTM to model complexity

Lecture-based introductory biology courses are typically content-heavy as instructors strive to provide students with foundational knowledge in a broad range of topics. One topic traditionally covered is cellular respiration, the series of...

Courses: Introductory Biology

ATPGlycolysisCellular RespirationElectron Transport ChainKrebs Cycle

Lesson

724

views

77

downloads

0

comments

Discovery and Invention: A Reflection on Representation in Science

Despite increased awareness of the lack of equity and inclusion in the STEMM classroom, lessons on DEI topics are treated as separate to the scientific curriculum being taught. Rarely are intentional reflections and conversations on the lack of...

Courses: Professional Development and Career Planning

EquityDiversity and Inclusionantiracism

Lesson

2664

views

990

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0

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Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography

Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking clearly about evolutionary trees (phylogenetics) and how...

Courses: Evolution Introductory Biology

EvolutionphylogeneticsTree thinkingbiogeography

Lesson

7669

views

368

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0

comments

Investigating Cell Signaling with Gene Expression Datasets

Modern molecular biology is a data- and computationally-intensive field with few instructional resources for introducing undergraduate students to the requisite skills and techniques for analyzing large data sets. This Lesson helps students: (i)...

Courses: Biochemistry and Molecular Biology Cell Biology

genomicstranscriptionsignaling

Lesson

3427

views

251

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0

comments

SEAS CURE: Exploring Coral Biology Across Scales

Complex biological concepts (like symbiosis and coral biology) that span multiple scales and cross disciplinary boundaries are often difficult for students to understand. This complexity is compounded by the challenges inherent to teaching and...

Courses: Anatomy-Physiology Cell Biology Ecology Ecology Introductory Biology Science Process Skills

microscopyAnatomySymbiosisMetabolismbleachinginvertebratedinoflagellate

Teaching Tools and Strategies

1546

views

302

downloads

0

comments

SCIENCE/Fiction: Modular Template for Class Design

We present a modular scaffold for designing an introductory seminar using speculative fiction and science papers to welcome university undergraduates to the biology major. A list of twelve possible topics is included, such as Memory, Parasites,...

Courses: Anatomy-Physiology Biochemistry and Molecular Biology Cell Biology Evolution Genetics Introductory Biology Neurobiology

geneticscell biologyneurosciencesystems biologyScience Fiction

Lesson

1086

views

136

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0

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Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Technologies like next-generation sequencing, proteomics, and high-throughput phenotyping have transformed the way we do biology. There is a continued need for scientists with computational skills to analyze biological data while understanding the...

Courses: Bioinformatics

computationpythonJupyter notebookFunctionscentral dogmaDictionaries

Lesson

2565

views

108

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0

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Film as a Powerful Tool for Increasing Awareness of the Importance of Belonging in STEM

People of color in STEM fields can face a variety of challenges with belonging due to structural, cultural, psychological, and institutional barriers. The professional development sessions described in this lesson involved using film as well as...

Courses: Professional Development and Career Planning

steminclusionfilmbelonging

Lesson

3021

views

517

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0

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A Student-Led Hearing on the Use of HeLa Cells in Research

In this role-playing case study, students will learn about the HeLa cell line and its origins while examining multiple perspectives surrounding the cell line and its uses. The goal of this case study is for students to use guided questions to...

Courses: Cell Biology Science Process Skills

bioethicsscience policycell culturedebateHeLa cellsinformed consentrole playsocial justice issues

Lesson

4920

views

2371

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0

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Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

The goal of this lesson is to introduce students to the lytic and lysogenic cycles of T4 and lambda bacteriophages, respectively, using student-centered pedagogies. Bacteriophages are viruses that infect bacteria and are either virulent or...

Courses: Microbiology

bacteriophagesLysogenic cycleLysogenyLytic cycle

Review

1438

views

199

downloads

0

comments

Workshop Report: Summer 2020 Virtual CRISPR in the Classroom

As innovations and developments in genome editing technologies using CRISPR-Cas systems progress, the need to disseminate relevant knowledge and build skills among the next generation of young scientists in undergraduate classrooms is vital. Our...

Courses: Biochemistry and Molecular Biology Bioinformatics Genetics Professional Development and Career Planning

geneticscrisprGenome Analysisgene editingbacterial immunity

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The Leaky Neuron: Understanding synaptic integration using an analogy involving leaky cups

Making Change Sustainable: Network for Integrating Bioinformatics into Life Sciences Education (NIBLSE) Meeting Review

A Fun Introductory Command Line Lesson: Next Generation Sequencing Quality Analysis with Emoji!

Transitioning Two-Stage Exams to an Online Class

Understanding Gastric Acid Secretion: An Active Learning Approach

Going Remote: An Online Adaptation to Using a Primary Cell Culture Model to Study the Neural Extracellular Matrix

Single Cell Insights Into Cancer Transcriptomes: A Five-Part Single-Cell RNAseq Case Study Lesson

Investigating Gene Expression and Cell Specialization in Axolotl Embryos

Sequence Similarity: An inquiry based and "under the hood" approach for incorporating molecular sequence alignment in introductory undergraduate biology courses

A simple way for students to visualize cellular respiration: adapting the board game MousetrapTM to model complexity

Discovery and Invention: A Reflection on Representation in Science

Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography

Investigating Cell Signaling with Gene Expression Datasets

SEAS CURE: Exploring Coral Biology Across Scales

SCIENCE/Fiction: Modular Template for Class Design

Central Dogma, Dictionaries, and Functions: Using Programming Concepts to Simulate Biological Processes

Film as a Powerful Tool for Increasing Awareness of the Importance of Belonging in STEM

A Student-Led Hearing on the Use of HeLa Cells in Research

Exploring the Lytic and Lysogenic Life Cycles of Bacteriophages

Workshop Report: Summer 2020 Virtual CRISPR in the Classroom

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