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    Potential Scenario
    119

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    37

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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
    paracetamolpharmacokineticsstomachsmall intestinesulfapyridine
    Article or Presentation
    106

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    46

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    2011-Carl_Leinbach-Beyond_Newton_law_of_cooling_estimation_of_time_since_death
    The estimate of the time since death. Thus, the time of death is strictly that, an estimate. However, the time of death can be an important piece of information in some coroner’s cases, especially those that involve criminal or insurance...
    Newton's Law of Coolingtime of deathdouble exponentialcoroner
    Modeling Scenario
    435

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    166

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    1-046-GoingViral-ModelingScenario
    Students participate in a simulation of the spread of a viral disease in the classroom and model the process with a logistic differential equation. The simulation uses random numbers and the entire class participates.
    simulationmathematical modeldatalogisticrandom number generatorfittingrandom process
    Potential Scenario
    178

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    67

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Potential Scenario
    164

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    40

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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
    Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol
    Potential Scenario
    98

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    32

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    2004-Hill-Lozowski-Sampson-Experiments on ice spikes and a simple growth model
    We observed ice-spike growth using time-lapse digital photography, using two water types in two different containers.
    iceice spikebulk heat transfermass conservation
    Potential Scenario
    180

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    53

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.
    mRNAlactoselactose operonfeedback regulation
    Potential Scenario
    118

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    48

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    1981-Nielsen-Rosenfeld-Substantive Interpretations of Differential Equation Models
    The use of differential equations models to study social processes has been increasing rapidly. There are, however, ambiguities in the interpretation of the parameters of these models.
    sociologypoliticsintragenerational mobilitypolitical mobility
    Article or Presentation
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    58

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    1981-Nielsen_Francois-Rachel_Rosenfeld-Substantive_Interpretations_of_Differential_Equation_Models
    The interpretation of parameters of dynamic models is illustrated with reference to research on two substantive topics: political mobilization and intragenerational mobility.
    differential equationsdynamical systemsFirst order linearintragenerational mobilitypolitical mobilizationmobility
    Modeling Scenario
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    1-005-OilSlick-ModelingScenario
    We describe a modeling activity with difference and differential equations which enlightens students on the model building process and parameter estimation for a linear, first-order, non-homogeneous, ordinary differential equation.
    model fittingspreadsheetsSpanishderrame de petróleodatosexpansiónoil slick
    Modeling Scenario
    355

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    213

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    1-097-SwimmingPool-ModelingScenario
    This project involves the dynamics of chlorine concentration during regular swimming pool maintenance cycles. Students will have the opportunity to use both analytic and numerical methods.
    concentrationcchlorinenumerical errorswimming poolhorineerreor
    Modeling Scenario
    394

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    297

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    1-061-PotatoCooling-ModelingScenario
    We model the cooling of a baked potato and compare it to student-collected data.
    least sum of square errorsNewton's Law of Coolingcoolingpotato
    Modeling Scenario
    261

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    244

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    1-110-TidePoolSnails-ModelingScenario
    Students use linear differential equations to model temperature change, in a sand tide pool and inside the shell of a snail in the tide pool. We offer data on temperature in a tide pool as the sun heats the water. Students model the tide pool's...
    datasnailstemperatureNewton's Law of CoolingcoolingNewtonwarmingtital pooltide pool
    Modeling Scenario
    286

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    132

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    1-115-ModelingWithFirstOrderODEs-ModelingScenario
    Several models using first order differential equations are offered with some questions on formulating a differential equations model with solutions provided.
    bacteriafalling objectNewton's Law of Coolingdrugcoolingdrag
    Modeling Scenario
    214

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    339

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    3-073-EarthQuakePartII-ModelingScenario
    Your goal here is to determine how much friction/damping should be designed into a building to keep the roof from moving too far (which would result in the entire building collapsing) when it undergoes minor vibrations from a small earthquake.
    earthquakevibrationdampingamplitudespring-mass systemsteady-state solutionunderdamped
    Modeling Scenario
    210

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    117

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    1-004-MicroorganismImmigration-ModelingScenario
    We present a modeling opportunity for population death with non-constant immigration and suggest the use of both discrete and continuous models with a comparison of results.
    continuousimmigrationpopulationdeathdiscrete
    Modeling Scenario
    229

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    256

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    1-002-Tossing-ModelingScenario
    We offer students simulation experience or data from a simulation and ask them to model the simulation using several approaches, to include exponential decay fit, difference equation, and differential equation.
    Modeling and simulationexponentialdecaydice
    Potential Scenario
    130

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    82

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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
    metabolic syndromecompartment modelcholesterolhigh blood cholesterol
    Potential Scenario
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    53

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    2017-Adolfo_Rumbos-Differential Equations and modeling
    The study of any phenomenon in the physical or biological sciences, in which continuity and differentiability assumptions about the quantities in question can be made, invariably leads to a differential equation, or a system of differential...
    pendulumLotka Volterra equationsexistenceuniqueness
    Potential Scenario
    115

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    72

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis