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Downloads
Views
Date
Relevance
Modeling Scenario
309
views
475
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Potential Scenario
104
views
39
downloads
0
comments
2004-Aldo_Rescigno-On the use of pharmacokinetic models
In this paper I will define in a simple and logical way a set of useful pharmacokinetic parameters and show how their estimation depends on the assumed model.
compartment
steady state
pharmacokinetics
volume distribution
Potential Scenario
121
views
45
downloads
0
comments
2019-Banuelos_Danet_Flores_Ramos-Epidemiological_Math_Model_Approach_To_Political_System_with_Three_Parties
A nonlinear compartmental model is derived to study the movement between classes of voters with the assumption of a constant population that is homogeneously mixed.
politics
parameters
voting
compartment model
epidemiological model
equilibria
three-party system
Potential Scenario
852
views
39
downloads
0
comments
2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
kinetics
SAS
compartment
pharmacokinetics
Modeling Scenario
290
views
467
downloads
0
comments
5-005-Dialysis-ModelingScenario
We design a compartment model of a kidney dialysis machine and compare 3 and 9 compartments for the machine as well as determine the effect of change in one of the parameters in the model on the effectiveness to deliver quality dialysis.
countercurrent multiplier
kidney
dialysis
concurrent
compartment
Potential Scenario
135
views
41
downloads
0
comments
2006-Ousmane_Mousa_Tessa-Mathematical model for control of measles by vaccination
In this article, we use a compartmental mathematical model of the dynamics of measles spread within a population with variable size to provide this framework.
vaccination
compartment
herd immunity
measles
optimal strategy
Potential Scenario
131
views
41
downloads
0
comments
2009-Noakes-Sleigh-Mathematical models for assessing the role of airflow on the risk of airborne infection in hospital wards
Understanding the risk of airborne transmission can provide important information for designing safe healthcare environments with an appropriate level of environmental control for mitigating risks.
infection
compartment
hospital
ventilation
airborne
sthochastic
Wells–Riley
Modeling Scenario
264
views
167
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Modeling Scenario
190
views
215
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Potential Scenario
115
views
34
downloads
0
comments
2005-P_Howard-Modeling with ODE
In these notes we consider three critical aspects in the theory of ordinary differential equations: developing models of physical phenomena, mathematically well-posed, solving ODE numerically .
Fluid Mechanics
compartment
populations
variational methods
Hamiltonian mechanics
Modeling Scenario
274
views
377
downloads
0
comments
1-065-AlgalBlooms-ModelingScenario
This modeling scenario investigates the massive algal blooms that struck Lake Chapala, Mexico, starting in 1994.
direction fields
tool:dfield
algae
harmful algae blooms
population
compartment
Lake Chapala
Modeling Scenario
188
views
183
downloads
0
comments
1-134-LanguageDynamics-ModelingScenario
Students will be introduced to a mathematical model for language dynamics. Specifically, the model describes the change in the fraction of a population speaking one language over another.
language
compartment
phase lines
bifurcation
switching
Potential Scenario
228
views
63
downloads
0
comments
2014-Blomhøj-EtAl-Compartment models
An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
concentration
kinetics
physiology
compartment
salt
tank
balance
reactions
mink
bathtub
Modeling Scenario
322
views
528
downloads
0
comments
6-007-FunctionsAndDerivativesInSIRModels-ModelingScenario
Given a system of differential equations, how do the solution graphs compare with the graphs of the differential equations? Students tackle this question using SIR models for well-known infectious diseases.
epidemiology
species interactions
derivatives
visualization
infection
SIR models
Law of Mass Action
Potential Scenario
144
views
73
downloads
0
comments
2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.
SAS
superposition
pharmacokinetics
compartmental models
multiple dose
Potential Scenario
118
views
37
downloads
0
comments
2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
paracetamol
pharmacokinetics
stomach
small intestine
sulfapyridine
Potential Scenario
142
views
62
downloads
0
comments
2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear systems.
compartment
heating
house
Potential Scenario
150
views
68
downloads
0
comments
2011-Nakul-Chitnis-Introduction to Mathematical Epidemiology - Deterministic Compartmental Model
Deterministic compartmental models form the simplest models in the mathematical study of infectious disease dynamics. They assume that a population is homogenous (all people are the same) and the only distinction is in their disease state.
sensitivity
disease
infection
threshold
compartment
bifrucation
Modeling Scenario
594
views
358
downloads
0
comments
5-011-ModelingIbuprofren-ModelingScenario
We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
data
AIC
Akaike Information Criterion
absorption
sum of square errors
compartment model
ibuprofen
delay
Modeling Scenario
199
views
223
downloads
0
comments
6-029-TumorGrowth-ModelingScenario
This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of tumor growth over time.
Pop_Growth Pilot
logistic
comparment
tumor
synthetic data
sum of squares error
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