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    Potential Scenario
    104

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    30

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
    longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics
    Article or Presentation
    129

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    56

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    SIMIODE Spring 2024 Webinars - WikiModel
    WikiModel is cloud-based application and requires no installation and is run via a web-browser to facilitate rapid implementation. Equations are typed in as they appear in a textbook. ODEs are automatically integrated via Runge-Kutta methods.
    modelingSoftwaretoolapplicationWikiModelmodeling cycle
    Potential Scenario
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    51

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    2016-Barbarossa-Kuttler-Mathematical Modeling of Bacteria Communication in Continuous Cultures
    This paper presents a simple system of delay differential equations (DDEs) for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed) negative feedback mechanism.
    gene regulatory networkschemostatbifurcationNumerical Simulationquorum sensing
    Potential Scenario
    159

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    40

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
    sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search
    Potential Scenario
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    46

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
    compartment modelpharmacokineticsnonlinear estimationone compartment model
    Potential Scenario
    131

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    42

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    2019-Fan_ Li_ Yin- Impact_of_environmental_tax_on_green_development-nonlinear_dynamical_system_analysis
    This study analyzes the impact of environmental tax on green development by using a four-dimension dynamical system.
    environmentsystemequilibrium pointmodel chaoseconomic growthnonlinear
    Technique Narrative
    280

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    115

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    1-009-Bifurcation-TechniqueNarrative
    We lead students to investigate first-order differential equations that contain unknown parameters. Students discover what happens to the qualitative behavior of solutions to these equations as these parameters vary.
    bifurcationqualitative behaviorbifurcation diagram
    Modeling Scenario
    270

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    171

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    1-092-DashItAll-ModelingSenario
    This project uses very basic physics, Newton's Second Law of Motion, to model the motion of a sprinter running down a track. We derive the classic Hill-Keller model for a sprinter exerting ``maximum'' effort as he/she accelerates down a track.
    datarunningsprintHill-Kellerworld recordOlympics
    Article or Presentation
    802

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    295

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    2020-TeachingModule-SpringDesignToMeetSpecsAtMinimumCosts
    We discuss a Modeling Scenario in which students are asked to design a spring mass system at minimum costs give relative costs of features of the spring.
    moduleoptimizationspring massmassspring\costTeaching Moduleminimal cost
    Article or Presentation
    155

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    412

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    1

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    2020-TeachingModule-ModelingFallingColumnOfWater
    We discuss how to model a falling column of water empirically and analytically from first principles in physics laws.
    modulecolumn of waterTorricelli's LawTorricelliTeaching Module
    Potential Scenario
    130

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    44

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    2017-Lia_Vas-Modeling With Differential Equations
    This is a set of class notes for Lia Vas in which examples from population, falling objects, tank mixing, growth and threshold, are offered.
    thresholdsfalling objectgrowthtank mixing
    Potential Scenario
    124

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    59

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    2017-Anders_Kallen-Single species models in continuous time
    Part of a series of Lecture notes this lecture contains rich materials on logistic harvest models, spruce budworms, and chemostat.
    chemostatlogisticharvestspruce budworm
    Potential Scenario
    135

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    47

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    2012-Murray_Bourne-Modeling fish stocks
    Discusses many models of harvesting and consequences.
    fishlogisticmanagementsusustainable developmentharvestfish stockoverpopulatedunsustainable
    Potential Scenario
    109

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    37

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    2012-Gilbert_Koch-Modeling of Pharmacokinetic and Pharmacodynamics of Cancer and Arthritis
    In this work we develop preclinical PKPD models based on fundamental biological and pharmacological principles. Equipped with a PKPD model, different dosing schedules could be simulated.
    cancerpharmacodynamicsPKPD modelarthritisPharmacokineticanticancer
    Potential Scenario
    116

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    38

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    2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
    This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
    absorptionMichaelis-MentenMetabolismdrug metabolismcirculation
    Potential Scenario
    116

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    35

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    2011-Carl_Leinbach-Beyond Newton's law of cooling - estimation of time since death
    The paper offers an excellent history of temperature-based methods and then proceeds to demonstrate these with some data. Here the history is rich and will support student investigation as well as faculty development.
    time of deathNewton's aw of cooling
    Potential Scenario
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    34

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    2008-Luis_San_Andrés-Dynamic Response of Second Order Mechanical Systems with Viscous Response Forces
    Walk through the cases in context of second order linear constant coefficient differential equation with driving function
    driving functionviscousmechanical system
    Potential Scenario
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    86

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    2005-Albert_Tarantola-Inverse Problem Theory and Methods for Model Parameter Estimation
    This is a bible of approaches to support parameter estimation approaches in inverse problems. Theory and algorithms are offers with examples.
    Algorithminverse probleminverse
    Potential Scenario
    126

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    55

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    2002-Ragnar-Norberg-Basic Life Insurance Mathematics
    Presents fundamentals of life insurance, mortality, savings, banks, finance, reserves, pensions, stochastic processes.
    financestochastic processessavingslife insurancebanksreservespensionsmortality
    Potential Scenario
    168

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    47

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    1967-JG-Wagner-Computers in pharmacokinetics
    This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.
    kineticscomputerspharmacokinetics