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    Potential Scenario
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    2018-Van_Kinh Nguyen-Esteban_Hernandez-Vargas-Parameter estimation in mathematical models of viral infections using R
    Mathematical modeling has played a central role to understand mechanisms in different viral infectious diseases. In this approach, biological-based hypotheses are expressed via mathematical relations and then tested based on empirical data.
    simulationdiseasevirusviral infection
    Potential Scenario
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    2013-Fathalla_Rihan-Delay Differential Equations in Biosciences - Parameter estimation and sensitivity analysis
    This is a review article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological phenomena such dynamical diseases and cell growth...
    epidemiologysensitivityImmunologyphysiologyRK-methodstime-lags
    Potential Scenario
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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.
    experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates
    Potential Scenario
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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.
    estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system
    Potential Scenario
    226

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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
    sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search
    Potential Scenario
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    2018-Akman-EtAl-Parameter Estimation in Ordinary Differential Equations Modeling via Particle Swarm Optimization
    We demonstrate Particle Swarm Optimization efficacy by showing that it outstrips evolutionary computing methods previously used to analyze an epidemic model.
    epidemicParticle Swarm Optimizationoptimize parameters
    Potential Scenario
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    87

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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer cells.
    cancertumorfittingagent-based
    Potential Scenario
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    2015-G_Knott-Chemical Kinetics - Simple Binding F + G to and from B
    The study of this reaction, F + G goes to and from B, is common in chemistry and biochemistry. For example, F could be a hormone or drug and G the associated receptor sites.
    bindingreactionchemical kineticsdeterministicBiochem Labsprobabilistickinetic reaction
    Potential Scenario
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    2014-Niemann-Miklos-Simple Method for Estimation of Parameters in First Order Systems
    A simple method for estimation of parameters in first order systems with time delays is presented in this paper.
    delaytime delystep response
    Potential Scenario
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    45

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    1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
    This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference equation model.
    drugstwo compartmentcocainedemand
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
    compartment modelpharmacokineticsnonlinear estimationone compartment model
    Potential Scenario
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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify different patterns of the steady state.
    dynamical systemsregulationsteady statesales modelexternal stimulus
    Potential Scenario
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    2000-Idels-Wang-Harvesting Fisheries Management Strategies With Modified Effort Function
    This study concludes that a control parameter beta (the magnitude of the effect of the fish population size on the fishing effort function E), changes not only the rate at which the population goes to equilibrium, but also the equilibrium values.
    sustainabilityfishFishingmanagementharvestfisherstrategyoverfishing
    Potential Scenario
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    2018-Adeniji-EtAl-InverseProblemHolling-TannerModel
    We consider the inverse problem of parameter identification of nonlinear system of ODEs for a specific case of complete information about solution of the Holling-Tanner model for finite number of points for the finite time interval.
    goal functionabsolute error curvesinvers methodholling-Tanner model
    Potential Scenario
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    2018-Weber_Theers_Surmann_Ligges_Weihs-Sensitivity Analysis_of_Ordinary_Differential_Equation_Models
    This report will focus on the sensitivity analysis of ordinary differential equation (ODE) models since they can be used to model so-called Low Frequency Oscillations (LFOs).
    sensitivityregressionparameter estimationsystemlow frequency oscillationsoscillations
    Potential Scenario
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    2017-Sim-EtAl-Optimal control of a coupled tanks system with model-reality differences
    In this paper, an efficient computational approach is proposed to optimize and control a coupled tanks system.
    optimal controlflowtankscoupled tanks
    Potential Scenario
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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Potential Scenario
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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Modeling Scenario
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    4-023-MysteryCircuit-ModelingScenario
    Students to build a system of differential equations which model a circuit. We give each student a unique input voltage frequency parameter and ask for system response (gain) to that input as a voltage over one of the resistors.
    filterscircuitRLC circuitKirchhoffvoltagegaindriver