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    Potential Scenario
    140

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response
    Potential Scenario
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    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
    anesthesiapharmacokineticspharmacodynamicanesthetic
    Potential Scenario
    133

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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics
    Potential Scenario
    182

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    50

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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time
    Potential Scenario
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    2016-Erno_Keszei-Chemical Kinetics for Beginners
    The most important goal of kinetic research is the identification and characterisation of elementary molecular events which make possible the transformation of reactants into products.
    kineticszeroth order reactionfirst order reactionsecond order reactionreaction ratesthird order reaction
    Potential Scenario
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    1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
    Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
    fishCell Membraneflowbloodbladdercountercurrent
    Modeling Scenario
    333

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    123

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    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    caffeineeliminationpharmacokineticsdrug
    Modeling Scenario
    336

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    537

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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    nullclinespharmacokineticsdigoxindrug eliminationtwo compartment
    Potential Scenario
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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Potential Scenario
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    75

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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub
    Modeling Scenario
    300

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    152

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    5-030-AirshedSulphur-ModelingScenario
    Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for analysis to predict long-term levels of levels of...
    sulphurpollutionairshedhydrogen sulfidesulfur dioxide
    Modeling Scenario
    244

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    182

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    3-042-CatapultLaunch-ModelingScenario
    We maximize the range of a projectile by backing up an incline in the opposite direction of the range to give some initial lift. Find the position on the hill from which to launch the projectile to give the best lift.
    projectile motioncatapultuphilllaunch angle
    Potential Scenario
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    2004-Ledzewicz-Schattler-Application of Control Theory in Modelling Cancer Chemotherapy
    In this paper we discuss how to incorporate more realistic medical aspects of chemotherapy which hitherto have been neglected in the models.
    optimal controldrug resistancepharmacokineticspharmacodynamicschemotherapy
    Potential Scenario
    142

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model
    Potential Scenario
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    2015-Sivakumar-EtAl-Approximate Analytical Expression of Concentrations in a Kinetic Model for Biogas Generation from Banana Waste
    The initial value problem in a kinetic model for biogas generation from banana waste is discussed. The model involves the system of non-linear differential equations which has variety of non-linear rate function.
    chemical kineticsMichaelis-Menten kineticsanaerobic digestionacidogenic stepsbananamethanogenic stepswastes
    Modeling Scenario
    650

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    394

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    5-011-ModelingIbuprofren-ModelingScenario
    We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
    dataAICAkaike Information Criterionabsorptionsum of square errorscompartment modelibuprofendelay
    Modeling Scenario
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    151

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    6-028-SaltCompartments-ModelingScenario
    Model a phenomena in which salt mixtures from two tanks are mixed with changing volumes of water.
    concentrationcomparmentsalttankmixing
    Modeling Scenario
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    3-051-ProjectileMotions-ModelingScenario
    We consider several instances of projectile flight without resistance, one on level ground and one from edge of cliff to determine maximum distance and placement.
    trajectorylaunching radiantprojectile motionprojectileno resistanceangle of launch
    Modeling Scenario
    184

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    3-052-OptimalProjectileFiring-ModelingScenario
    We offer the opportunity to model a projectile's trajectory in several cases, all without resistance.
    projectile motionprojectilelaunch anglemaximum range
    Potential Scenario
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    2011-Mandal-EtAl-Mathematical models of malaria
    The first aim of this article is to develop, starting from the basic models, a hierarchical structure of a range of deterministic models of different levels of complexity. The second is to elaborate, using some of the representative mathematical...
    epidemiologytransmissionhost-parasitemalariaRoss model