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    Potential Scenario
    274

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    68

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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Modeling Scenario
    201

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    227

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Modeling Scenario
    470

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    191

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
    wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue
    Potential Scenario
    139

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    57

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model
    Potential Scenario
    147

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    50

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    2004-Jones-Song-Thomas-Controlling wound healing through debridement
    In this article, a system of differential equations that models slough/wound interaction is developed.
    bacteriawound healinghealingderidingisocline
    Potential Scenario
    123

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    73

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    Potential Scenario
    130

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    51

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Potential Scenario
    1087

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    43

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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Modeling Scenario
    327

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    521

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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    nullclinespharmacokineticsdigoxindrug eliminationtwo compartment
    Potential Scenario
    206

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    96

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    2001-Smith-Moore-The SIR Model for Spread of Disease
    A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.
    epidemicSIR modelEuler's methodherd immunityHong Kong flu
    Potential Scenario
    233

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    92

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    2017-Xiang_Liu-Mathematical Studies of Optimal Economic Growth Model with Monetary
    In this paper, efforts will be made to study an extended Neoclassic economic growth model derived from Solow-Swan Model and Ramsey-Cass-Koopsman Model.
    Optimal Control TheoryJacobianSolow-Swan modelMonetary policyoptimal economic growth
    Potential Scenario
    225

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    63

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.
    population dynamicsLotka-Volterragrowth ratemutualismLichen
    Potential Scenario
    140

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    50

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    0

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
    compartment modelpharmacokineticsnonlinear estimationone compartment model
    Potential Scenario
    351

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    58

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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify different patterns of the steady state.
    dynamical systemsregulationsteady statesales modelexternal stimulus
    Potential Scenario
    220

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    71

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving fourteen parameters.
    stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates
    Potential Scenario
    122

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    60

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    2014-Murillo-EtAl-Vertical Transmission in a Two-Strain Model of Dengue Fever
    The model is used to show that lower transmission rates of DENV-2 Asian are sufficient for displacing DENV-2 American in the presence of vertical transmission.
    Peruvector-host modeldengueepidemmiologyvertical transmission
    Potential Scenario
    194

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    55

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.
    mRNAlactoselactose operonfeedback regulation
    Potential Scenario
    108

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    42

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    2001-Edwards-Buckmire-A differential equation model of North American cinematic box-office dynamics
    A new mathematical model is presented for the box-office dynamics of a motion picture released in North America.
    cinemamoviesbox-office
    Potential Scenario
    126

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    47

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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.
    Biomathematicspharmacokinetics
    Potential Scenario
    160

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    49

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    2018-Weber_Theers_Surmann_Ligges_Weihs-Sensitivity Analysis_of_Ordinary_Differential_Equation_Models
    This report will focus on the sensitivity analysis of ordinary differential equation (ODE) models since they can be used to model so-called Low Frequency Oscillations (LFOs).
    sensitivityregressionparameter estimationsystemlow frequency oscillationsoscillations