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Downloads
Views
Date
Relevance
Potential Scenario
200
views
87
downloads
0
comments
1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
LSD
compartment
pharmacokinetics
Potential Scenario
139
views
87
downloads
0
comments
2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.
metabolic syndrome
compartment
cholesterol
two-compartment model
cholesterol transport
Potential Scenario
106
views
41
downloads
0
comments
1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference equation model.
drugs
two compartment
cocaine
demand
Potential Scenario
274
views
68
downloads
0
comments
1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
LSD
correlation coefficient
compartment model
lysergic acid diethylamide
performance
test score
tissue concentration
Potential Scenario
122
views
47
downloads
0
comments
2012-Arvind_Kumar_Misra-A simple mathematical model for the spread of two political parties
In this paper, a non-linear mathematical model for the spread of two political parties has been proposed and analyzed by using epidemiological approach.
epidemic
compartment
political parties
Modeling Scenario
1164
views
5459
downloads
0
comments
5-001-LSD-ModelingScenario
We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
LSD
Spanish
compartment
pharmacokinetics
lysergic acid diethylamide
Potential Scenario
129
views
55
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
135
views
79
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Potential Scenario
123
views
73
downloads
0
comments
2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
metabolic syndrome
cholesterol
high blood cholesterol
cholesterol homeostasis
Modeling Scenario
327
views
521
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Modeling Scenario
278
views
211
downloads
0
comments
1-086-MedicinalPill-ModelingScenario
Administration of a medicinal pill in single and multiple doses is modeled.
medicine
spillover
compartment
bloodstream
GIT-Track
Potential Scenario
120
views
35
downloads
0
comments
1999-PS_Crooke-S_Hota_JJ_Martini-JR_Hochkiss-A Mathematical Model for Carbon Dioxide Exchange
A mathematical model is presented to study the effect of Tracheal Gas Insufflation (TGI) on the alveolar ventilation during passive, mechanical ventilation.
mechanical ventilation
ventilation
carbon dioxide exchange
tracheal gas insufflation
alveolar ventilation
shunt
two-compartment model
Potential Scenario
219
views
51
downloads
0
comments
1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
sum of square errors
least squares
pharmacokinetics
lineteics
compartmental models
direct search
Potential Scenario
116
views
51
downloads
0
comments
2004-Aldo_Rescigno-On the use of pharmacokinetic models
In this paper I will define in a simple and logical way a set of useful pharmacokinetic parameters and show how their estimation depends on the assumed model.
compartment
steady state
pharmacokinetics
volume distribution
Potential Scenario
1087
views
43
downloads
0
comments
2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
kinetics
SAS
compartment
pharmacokinetics
Modeling Scenario
201
views
227
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Potential Scenario
268
views
74
downloads
0
comments
2014-Blomhøj-EtAl-Compartment models
An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
concentration
kinetics
physiology
compartment
salt
tank
balance
reactions
mink
bathtub
Potential Scenario
156
views
70
downloads
0
comments
2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear systems.
compartment
heating
house
Potential Scenario
130
views
45
downloads
0
comments
2019-Banuelos_Danet_Flores_Ramos-Epidemiological_Math_Model_Approach_To_Political_System_with_Three_Parties
A nonlinear compartmental model is derived to study the movement between classes of voters with the assumption of a constant population that is homogeneously mixed.
politics
parameters
voting
compartment model
epidemiological model
equilibria
three-party system
Modeling Scenario
663
views
215
downloads
0
comments
5-026-Evictions-ModelingScenario
In this project, students develop two SIS models to study eviction trends in a population of non-homeowner households using an actual eviction rate. Students can calculate solutions, sketch the phase portrait, and determine long-term trends .
carrying capacity
compartment
eviction
homeowner
SIS model
homelessness
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