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    Potential Scenario
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    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.
    Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate
    Potential Scenario
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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time
    Potential Scenario
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    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
    paracetamolpharmacokineticsstomachsmall intestinesulfapyridine
    Potential Scenario
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    2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
    This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
    absorptionMichaelis-MentenMetabolismdrug metabolismcirculation
    Potential Scenario
    138

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    53

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Potential Scenario
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    1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
    Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
    LSDcompartmentpharmacokinetics
    Modeling Scenario
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    5-001-LSD-ModelingScenario
    We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
    LSDSpanishcompartmentpharmacokineticslysergic acid diethylamide
    Potential Scenario
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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics
    Potential Scenario
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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response
    Modeling Scenario
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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Modeling Scenario
    312

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    297

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    1-114-EarthClimate-ModelingScenario
    In this modeling scenario, we investigate the Earth's climate using a zero-dimensional energy balance model. Energy balance models are climate models that try to predict the average surface temperature of the Earth.
    climateenergytemperaturelinearizationphase linesenergy balance modelroot finding
    Potential Scenario
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    2010-Singh-Mishra-athematical modeling approach to study growth rate of grassroots technological innovations
    In this paper we have proposed a simple mathematical model by using ordinary differential equation to know the spread rate of technological innovations in rural India.
    logisticexponentialsigmoidtechnological innovationsasymptoticspread of innovation
    Potential Scenario
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    1989-EY_Rodin-K_Egan-Mathematics modelling of the rate of chemical reactions
    The development of improved designs for chemical reactors as well as the prediction of optimal operating conditions in chemical production are based on an understanding of the rates at which chemical processes occur.
    kineticsfirst orderreactionsecond orderzeroth order
    Modeling Scenario
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    1-124-WorldPopulation-ModelingScenario
    We build models of world population using data to estimate growth rate.
    population dynamicshumangrowth ratevarying growth rate
    Modeling Scenario
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    1-026-Evaporation-ModelingScenario
    We provide data on evaporation of 91% isopropyl alcohol in six different Petri dishes and one conical funnel and on evaporation of water in one Petri dish. We ask students to develop a mathematical model for the rate of change in the respective...
    evaporationconealcoholPetri dish
    Potential Scenario
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    2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
    From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages of expected future short rates.
    financeinterest ratebond yieldmacroeconomics
    Potential Scenario
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    95

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    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
    mathematical modeldataLSDMetabolismbloodstreamlysergic acid diethylamidedistribution
    Modeling Scenario
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    7-040-TankInterruptMixing-ModelingScenario
    We present a first order differential equation model for the interrupted mixing of a tank with salt water. We offer two solution strategies (1) two step approach and (2) Laplace Transforms.
    Laplace transforminverse Laplace Transformsalttankmixinginterrupt
    Modeling Scenario
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    1-085-DrugBolus-ModelingScenario
    Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
    concentrationsum of square errorsbolusdrugrate constantadminister
    Potential Scenario
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    2018-Franklin_Chen-Teaching Kinetics through Differential Equations Constructed with a Berkeley MadonnaTM Flow Chart Model
    This kinetics manual has been successfully implemented in Physical Chemistry at UW-Green Bay in the fall semester of 2017, with the students’ success rate greater than 80%.
    kineticsPhysical ChemistryLotka Volterra equationsBerkeley Madonna platform