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    Modeling Scenario
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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Modeling Scenario
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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
    wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue
    Modeling Scenario
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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    nullclinespharmacokineticsdigoxindrug eliminationtwo compartment
    Potential Scenario
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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Potential Scenario
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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
    metabolic syndromecompartment modelcholesterolhigh blood cholesterol
    Potential Scenario
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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    Modeling Scenario
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    1-130-AspirinAbsorption-ModelingScenario
    We model the amount of aspirin absorbed by the human body at a constant rate. This is a ``zero-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    pharmacokineticsdrugaspirin
    Modeling Scenario
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    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    caffeineeliminationpharmacokineticsdrug
    Potential Scenario
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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model
    Potential Scenario
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    2004-Jones-Song-Thomas-Controlling wound healing through debridement
    In this article, a system of differential equations that models slough/wound interaction is developed.
    bacteriawound healinghealingderidingisocline
    Modeling Scenario
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    3-009-BallDropInWater-ModelingScenario
    We conduct an analysis of a falling ball in liquid to determine its terminal velocity and to ascertain just what radius ball for a given mass density is necessary to attain a designated terminal velocity.
    resistancegravityfalling bodyterminal velocitybuoyancy
    Modeling Scenario
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    1-071-NewtonWatson-ModelingScenario
    Sherlock Holmes determines the time of death for a body found on a street in London and we need to reproduce his astute analysis
    temperaturedeathNewton's Law of Coolingtime of deathSherlock Holmes
    Modeling Scenario
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    3-030-SecondOrderIntro-ModelingScenario
    We outline the solution strategies involved in solving second-order, linear, constant coefficient ordinary differential equations, both homogeneous and nonhomogeneous and offer many application and modeling activities.
    parameter estimationnon-homogeneousSpanishfrequencybuoyancyinverse problemthrustunderdampedfirst passagespring mash dashpotrealcomplexhomogeneoussuperpositionparachuteoverdampedcritically dampedbuoyquadratic equationrootsrocket flight
    Modeling Scenario
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    5-014-TwoSpringMass-ModelingScenario
    We ask students to build a Free Body Diagram for a vertical two mass situation in which the two masses are held fixed at the tip and at the bottom. The mass holds the springs together at the join of the two springs in between.
    massspring mass dampersprings
    Potential Scenario
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    2003-Bohren-Dimensional analysis-falling bodies--fine art of not solving differential equations
    Dimensional analysis is a simple, physically transparent and intuitive method for obtaining approximate solutions to physics problems, especially in mechanics.
    falling bodydimensional analysisdrag
    Modeling Scenario
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    1-061-PotatoCooling-ModelingScenario
    We model the cooling of a baked potato and compare it to student-collected data.
    least sum of square errorsNewton's Law of Coolingcoolingpotato
    Potential Scenario
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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Modeling Scenario
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    1-128-RocketFlight-ModelingScenario
    We offer an opportunity to build a mathematical model using Newton's Second Law of Motion and a Free Body Diagram to analyze the forces acting on the rocket of changing mass in its upward flight under power and then without power followed by its...
    resistanceFlightRocketrymassNewton's Second Law of MotionthrustFree Body Diagramapexrocket
    Modeling Scenario
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    1-100-EngineeringDemographics-ModelingScenario
    Students show how models can be used to examine social issues. The students examine three different models and use numerical methods to apply each model to demographic data for the percentage of engineering degrees awarded to women in the United...
    logisticpopulationImproved Euler MethodGompertzdemographicswomenautonomous
    Modeling Scenario
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    6-012-RiverCrossing-ModelingScenario
    Students develop a model of a river crossing in a boat with thrust using Newton's Second Law of Motion from a Free Body Diagram they construct. The model is thence a system of one second order linear and a second order nonlinear differential...
    dragonNewton's Second Law of Motionriver crossinriver currentvelocity profilethrustFree Body Diagram