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    Potential Scenario
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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Potential Scenario
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    47

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
    longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics
    Potential Scenario
    361

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    62

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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify different patterns of the steady state.
    dynamical systemsregulationsteady statesales modelexternal stimulus
    Potential Scenario
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    2010-Kijek-Kijek-Modelling of Innovation Diffusion
    This paper offers a first order differential equation model for innovation diffusion, solves it, and offers qualitative analysis as well as approaches to estimating parameters with some data on final parameters for various countries.
    Bass modelinnovation diffusionLogistic modeldynamic model
    Potential Scenario
    135

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    1981-Nielsen-Rosenfeld-Substantive Interpretations of Differential Equation Models
    The use of differential equations models to study social processes has been increasing rapidly. There are, however, ambiguities in the interpretation of the parameters of these models.
    sociologypoliticsintragenerational mobilitypolitical mobility
    Potential Scenario
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    2018-Arden_Baxter-Modeling Public Opinion
    In this paper, we adapt the epidemiological models to model the dynamics of public opinion. Public opinion is any view prevalent among the general public. Our model considers any topic or issue in which the public has two decisive and opposing...
    epidemiologypopulationpublic opinion
    Modeling Scenario
    275

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    135

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    1-143-PopulationModelVariationsMATLAB-ModelingScenario
    Students will walk through a detailed derivation and review of basic population models (exponential and logistic) to create and understand variations of those models.
    population dynamicsecologylogistic growthbifurcation theoryslope fieldsextinctionharvestingqualitative analysisstocking
    Potential Scenario
    132

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    48

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    2007-Ramsay-Hooker-Campbell-Cao-Parameter estimation for differential equations-a generalized smoothing approach
    We propose a new method for estimating parameters in models that are defined by a system of non-linear differential equations.
    estimating equationfunctional data analysisGauss–Newton methodparameter cascadeprofiled estimationdynamic system
    Potential Scenario
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    69

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    2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
    From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages of expected future short rates.
    financeinterest ratebond yieldmacroeconomics
    Potential Scenario
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    93

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.
    cancertumor modelingangiogenesistumor growthpatient care
    Free Online Textbook
    143

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    67

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    2015-H_Sayama-Intro to Modeling and Analysis of Complex Systems
    Introduces students to mathematical/computational modeling and analysis developed in the emerging interdisciplinary field of Complex Systems Science.
    textbooktext
    Modeling Scenario
    298

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    272

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    1-098-NeuronDetection-ModelingScenario
    Students study a linear, first order, one-dimensional ordinary differential equation (ODE) and learn how it can help understand basics of neural dynamics. The modeling framework is known in mathematical neuroscience as ``integrate-and-fire''...
    biologyneuroscienceneuron physiologyvoltageintegrate and firethrefholscoincidence detectionRC circuit
    Modeling Scenario
    250

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    499

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    3-004-VanderPol-ModelingScenario
    This paper presents an electronic spreadsheet model of the Van der Pol oscillator, a well-known nonlinear second-order ordinary differential equation.
    phase planeVan der Pol oscillatorlimit cycleRunge-Kutta methodLienard equation
    Potential Scenario
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    85

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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
    134

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    52

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Modeling Scenario
    447

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    360

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    1-150-CancerTherapy-ModelingScenario
    This activity builds upon elementary models on population growth. In particular, we compare two different treatment models of cancer therapy where in one, surgery happens before therapy and in the other, surgery happens after therapy.
    population dynamicsphage therapyexponential growthcancerwater treatmentdecaysurgery
    Free Online Textbook
    464

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    96

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.
    spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions
    Potential Scenario
    155

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    2014-John_Cimbala-Dynamic System Response
    In this learning module, we discuss the dynamic system response of sensors and their associated electronic circuits.
    sensor networksoscillationssystem responseelectronic circuit
    Potential Scenario
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    39

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    2008-Luis_San_Andrés-Dynamic Response of Second Order Mechanical Systems with Viscous Response Forces
    Walk through the cases in context of second order linear constant coefficient differential equation with driving function
    driving functionviscousmechanical system
    Potential Scenario
    219

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    2008-Lawson-Marion-An Introduction to Mathematical Modelling
    This is a broad based set of notes with sections: Building Models, Studying Models, and Using Models. No depth on any model, no solution strategies, but good references to models, and general approaches that apply in most situations are offered.
    time serieslinear regressionAkaike Information Criterionmcomparision models