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    Potential Scenario
    283

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    73

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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Modeling Scenario
    211

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    242

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Modeling Scenario
    478

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    196

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
    wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue
    Potential Scenario
    203

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    92

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    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
    mathematical modeldataLSDMetabolismbloodstreamlysergic acid diethylamidedistribution
    Potential Scenario
    1249

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    47

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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Potential Scenario
    186

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    74

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    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng
    Potential Scenario
    132

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    77

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    Modeling Scenario
    355

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    223

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    1-045-TimeOfDeath-ModelingScenario
    Students are asked to determine the time of death given both environmental temperature situations and two observations of body temperature under several different circumstances.
    body masstemperaturedeathNewton's Law of Coolingbody temperature
    Modeling Scenario
    310

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    179

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    1-071-NewtonWatson-ModelingScenario
    Sherlock Holmes determines the time of death for a body found on a street in London and we need to reproduce his astute analysis
    temperaturedeathNewton's Law of Coolingtime of deathSherlock Holmes
    Modeling Scenario
    430

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    331

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    1-061-PotatoCooling-ModelingScenario
    We model the cooling of a baked potato and compare it to student-collected data.
    least sum of square errorsNewton's Law of Coolingcoolingpotato
    Modeling Scenario
    335

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    242

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    1-100-EngineeringDemographics-ModelingScenario
    Students show how models can be used to examine social issues. The students examine three different models and use numerical methods to apply each model to demographic data for the percentage of engineering degrees awarded to women in the United...
    logisticpopulationImproved Euler MethodGompertzdemographicswomenautonomous
    Modeling Scenario
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    3-065-UpDown-ModelingScenario
    We model the height of a launched object which is subject to resistance proportional to velocity during its flight. We ask questions about the motion as well, e.g., highest point or apex and terminal velocity.
    terminal velocityNewton's Second Law of Motionvelocitymotionapex
    Modeling Scenario
    312

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    276

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    3-013-WhiffleBallFall-ModelingScenario
    We are given data on the time and position of a whiffle ball as it falls to the ground. We attempt to model the falling ball and we confront the different resistance terms and models.
    Akaike Information CriterionresistancegravityFree Body Diagramforcefalling objectWhiffle ball
    Article or Presentation
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    54

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    2011-Carl_Leinbach-Beyond_Newton_law_of_cooling_estimation_of_time_since_death
    The estimate of the time since death. Thus, the time of death is strictly that, an estimate. However, the time of death can be an important piece of information in some coroner’s cases, especially those that involve criminal or insurance...
    Newton's Law of Coolingtime of deathdouble exponentialcoroner
    Potential Scenario
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    52

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    2014-Groetsch-Yost-Vertical Projection in a Resisting Medium - Revelations on Observations of Mersenne
    This article, inspired by a 17th-century woodcut, validates empirical observations of Marin Mersenne (1588–1648) on timing of vertically-launched projectiles for a general mathematical model of resistance.
    resistanceprojectile
    Modeling Scenario
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    284

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    1-055-WaterFallingInCone-ModelingScenario
    We offer an opportunity to model the height of a falling body of water in a right circular cone (funnel) and to estimate an appropriate parameter based on data collected from a video of the experiment found on YouTube.
    Torricelli's Lawdischarge coefficientconecontraction coefficient
    Modeling Scenario
    293

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    231

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    1-086-MedicinalPill-ModelingScenario
    Administration of a medicinal pill in single and multiple doses is modeled.
    medicinespillovercompartmentbloodstreamGIT-Track
    Modeling Scenario
    349

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    415

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    3-006-Buoyancy-ModelingScenario
    We offer data from a physical experiment in which the depth of a container in water is measured and ask students to build a model of buoyancy based on Newton's Second Law of Motion and a Free Body Diagram. We ask students to estimate the parameters.
    data collectionexperimentbuoyancyNewton's Second Law of Motion
    Modeling Scenario
    300

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    158

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    3-015-StyrofoamBallFall-ModelingScenario
    We are given data on a falling Styrofoam ball and we seek to model this motion.
    footballresistancegravityfalling bodysum of square errorsNewton's Second Law of Motionsum of forcesstyrofoam
    Modeling Scenario
    350

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    279

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    3-017-StackedCoffeeFiltersFalling-ModelingScenario
    Data on free falling 2, 4, 6, and 8 stacked coffee filters is offered. Students form a model using a resistance term proportional to velocity, velocity squared, or velocity to some general power. Parameters need to be estimated and models compared.
    dataresistancefalling bodycoffee filterstacked