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    Potential Scenario
    176

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    2017-Helen-Byrne-Further Mathematics Biology
    These studies will be in the context of ecological, biological and biochemical applications.
    epidemicschemotaxisenzyme-substrateion channelsnerve pulsesgene proagationtumour
    Potential Scenario
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    2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
    In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear systems.
    compartmentheatinghouse
    Free Online Textbook
    467

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    98

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.
    spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions
    Potential Scenario
    119

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    53

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters particularly suited to situations where noise levels are...
    time seriesEvaluation SPLINEgeneleast squaresbifurcation
    Potential Scenario
    202

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    73

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Potential Scenario
    224

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    2011-Lucas_Pulley-Analyzing Predator-Prey Models Using Systems of Ordinary Linear Differential Equations
    This research focused on applying biological mathematics to analyzing predation relationships, especially the relationship between the Canadian Lynx and the Snowshoe Hare.
    simulationpredator-preyLotka-VolterrapopulationCanadian LynxSnowshoe Harecritical values
    Potential Scenario
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    49

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.
    experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates
    Potential Scenario
    296

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological processes.
    protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular
    Potential Scenario
    161

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    63

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    2018-Dyjuan_Tatro-The_Mathematics_of_Cancer-Fitting_Gompertz_Equation_to_Tumor_Growth
    Fitting the Gompertz Model to long term breast cancer study data, this project ascertains gompertzian parameters that can be used to predicts tumor growth as a function of time.
    tumorgrowthGompertzfittingparameter
    Potential Scenario
    280

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    98

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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.
    simulationNetLogopredator-preyagent-basedwolffox
    Potential Scenario
    120

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    61

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    2014-Niemann-Miklos-Simple Method for Estimation of Parameters in First Order Systems
    A simple method for estimation of parameters in first order systems with time delays is presented in this paper.
    delaytime delystep response
    Potential Scenario
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    51

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    2011-GA_Koch-Noble-Drugs in the Classroom Using Pharmacokinetics to Introduce Biomathematical Modeling
    By beginning with simple model involving the half-life of a drug, students take advantage of their mathematical abilities to explore the biology.
    Biomathematicspharmacokinetics
    Potential Scenario
    1249

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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Potential Scenario
    186

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    74

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    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng
    Modeling Scenario
    270

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    143

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    3-091-SpringModeling-ModelingScenario
    In this lab students will collect data on their spring mass systems and compare their empirical models to their theoretical ones—giving them an opportunity to actually test a model against data.
    datalaboratoryLoggerProVerniermass-spring systemmodel validationempirical modeltheoretical model
    Potential Scenario
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    2014-Allen-EtAl-Perturbations in Epidemiological Models -When zombies attack we can survive
    In this paper, we investigate the existence of stability-changing bifurcations in epidemiological models used to study the spread of zombiism through a human population.
    epidemiologydynamical systemszombiesbifurcationperturbation
    Potential Scenario
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    2013-Greer-EtAl-Collaborative Understanding of Cyanobacteria in Lake Ecosystems
    We describe here a collaboration in which the mathematicians help collect data, the ecologists synthesize more data from model output than they can produce empirically, and the collaboration produces both mathematical approaches and field work.
    collaborationlakeecosystemcyanobacteriafield workcolonyGloeo
    Potential Scenario
    363

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    2018-Hu-Huang-Dynamic Regulation Responding to an External Stimulus
    This study examines the dynamic regulation process responding to an external stimulus. This study introduces the driven damped oscillator model which has an additional parameter to identify different patterns of the steady state.
    dynamical systemsregulationsteady statesales modelexternal stimulus
    Potential Scenario
    180

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    2016-Starling-EtAl-Local Brewery - A Project for Use in Differential Equations Courses
    We describe a modeling project designed for an ordinary differential equations (ODEs) course using first-order and systems of first-order differential equations to model the fermentation process in beer.
    BEERFermentationbrewery
    Potential Scenario
    285

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    79

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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub