Resources

Text Search:
Applied Filters
    Potential Scenario
    274

    views

    68

    downloads

    0

    comments

    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    Potential Scenario
    177

    views

    49

    downloads

    0

    comments

    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    Potential Scenario
    192

    views

    68

    downloads

    0

    comments

    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
    Modeling Scenario
    304

    views

    219

    downloads

    0

    comments

    1-085-DrugBolus-ModelingScenario
    Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
    Potential Scenario
    135

    views

    79

    downloads

    0

    comments

    Modeling Scenario
    369

    views

    440

    downloads

    0

    comments

    1-011A-Kinetics-ModelingScenario
    We help students see the connection between college level chemistry course work and their differential equations coursework. We do this through modeling kinetics, or rates of chemical reaction.
    Modeling Scenario
    201

    views

    227

    downloads

    0

    comments

    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    Modeling Scenario
    470

    views

    191

    downloads

    0

    comments

    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
    Potential Scenario
    129

    views

    55

    downloads

    0

    comments

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    Potential Scenario
    268

    views

    74

    downloads

    0

    comments

    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    Modeling Scenario
    260

    views

    362

    downloads

    0

    comments

    1-094-SteepingTea-ModelingScenario
    We provide photographs of steeping process for a tea steeped in hot water. Students build a differential equation model for the steeping process and do parameter estimation using the color of our tea as a way to measure relative concentration.
    Potential Scenario
    197

    views

    85

    downloads

    0

    comments

    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
    Potential Scenario
    1087

    views

    43

    downloads

    0

    comments

    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    Potential Scenario
    177

    views

    72

    downloads

    0

    comments

    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    Potential Scenario
    131

    views

    70

    downloads

    0

    comments

    2016-Erno_Keszei-Chemical Kinetics for Beginners
    The most important goal of kinetic research is the identification and characterisation of elementary molecular events which make possible the transformation of reactants into products.
    Potential Scenario
    165

    views

    44

    downloads

    0

    comments

    2015-Sivakumar-EtAl-Approximate Analytical Expression of Concentrations in a Kinetic Model for Biogas Generation from Banana Waste
    The initial value problem in a kinetic model for biogas generation from banana waste is discussed. The model involves the system of non-linear differential equations which has variety of non-linear rate function.
    Potential Scenario
    123

    views

    73

    downloads

    0

    comments

    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    Potential Scenario
    304

    views

    54

    downloads

    0

    comments

    1976-JG-Wagner-Computers in pharmacokinetics
    This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.
    Potential Scenario
    135

    views

    44

    downloads

    0

    comments

    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.