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Modeling Scenario
208
views
239
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Modeling Scenario
476
views
194
downloads
0
comments
5-012-LipoproteinModeling-ModelingScenario
Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
wildlife
low-density-lipoprotein
tracer
compartment model
cholesterol
blood plasma
body tissue
Modeling Scenario
336
views
537
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Potential Scenario
1248
views
47
downloads
0
comments
2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
kinetics
SAS
compartment
pharmacokinetics
Potential Scenario
183
views
74
downloads
0
comments
1996-D_Erdman-MM_Morelock-A Study of Kinetics
This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
simulation
kinetics
parameter estimation
Enzyme
substrate
savings
compartment
stomach
blood
ginseng
Potential Scenario
134
views
52
downloads
0
comments
2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
QUBES Leadership Team
parameters
absorption
bifurcation
pharmacokinetics
calcium
cognitive decline
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