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Downloads
Views
Date
Relevance
Potential Scenario
173
views
65
downloads
0
comments
1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We model this.
LSD
score
plasma
lysergic acid diethylamide
human subjuects
Potential Scenario
160
views
48
downloads
0
comments
1969-Carl_Metzler-A mathematical model for the pharmacokinetics of LSD effect
Contains data on performance scores vs. plasma levels of LSD in human tissues.
LSD
testing
pharmacokinetics
performance
plasma level
Modeling Scenario
208
views
239
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Modeling Scenario
476
views
194
downloads
0
comments
5-012-LipoproteinModeling-ModelingScenario
Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
wildlife
low-density-lipoprotein
tracer
compartment model
cholesterol
blood plasma
body tissue
Modeling Scenario
297
views
178
downloads
0
comments
5-010-DNADegradation-ModelingScenario
We ask students to use the system of first order linear differential equations given in a source paper and estimates of the data from laboratory procedures from a plot to estimate the parameters and complete the modeling process.
DNA\kinetis
plasma
rat
pharmacokinetis
Potential Scenario
164
views
43
downloads
0
comments
1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.
p
Pharmacology
pharmacokinetics
lidocaine
Modeling Scenario
336
views
537
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Free Online Textbook
189
views
54
downloads
0
comments
2012-Vivek_Patel-Chemical Kinetics
The book is designed to help the reader, particularly students, researchers, research scholars, scientists, chemists and industry fraternity of chemistry and allied fields; understand the mechanics and reactions rates.
kinetics
chemistry
reaction
Potential Scenario
238
views
57
downloads
0
comments
1967-JG-Wagner-Computers in pharmacokinetics
This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.
kinetics
computers
pharmacokinetics
Modeling Scenario
377
views
441
downloads
0
comments
1-011A-Kinetics-ModelingScenario
We help students see the connection between college level chemistry course work and their differential equations coursework. We do this through modeling kinetics, or rates of chemical reaction.
kinetics
Law of Mass Action
fitting
order of reaction
chemical reaction
Potential Scenario
134
views
52
downloads
0
comments
2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
QUBES Leadership Team
parameters
absorption
bifurcation
pharmacokinetics
calcium
cognitive decline
Modeling Scenario
320
views
335
downloads
0
comments
5-024-PhGreatLakes
In this teaching modeling scenario, we demonstrate how lessons on salt-tank compartmental modeling can be used to predict phosphorus levels in the Great Lakes.
Great Lakes
limnology
comparment
pollution
compartmental models
phosphorous
Potential Scenario
158
views
69
downloads
0
comments
2017-William_Bialek-Boxes and Arrows To Differential Equations
This material uses pictures to build kinetic models of reactions and then offers analytic solutions.
Michaelis-Menten
Enzyme
substrate
DNA\kinetis
Potential Scenario
195
views
83
downloads
0
comments
2017-Jean-Roux-Mathematical Models in Air Quality Problems
Presents many models with analysis in air quality control. Starts with chemical kinetics models and builds complexity to PDE models.
air pollution effects on forest ecosystems
finite volume method
boundary layer
chemical kinetics
finite difference
emissions
depositions
advection
Potential Scenario
240
views
79
downloads
0
comments
2017-Floyd_Ballard-Dice Activities for DE Models
This document includes descriptions of four activities that are appropriate for a calculus or differential equations class, all using dice to motivate a differential equation model for a real-world scenario.
simulation
curve fitting
c
dice
collect data
class activities
analyze data
class activity
Potential Scenario
121
views
105
downloads
0
comments
2015-G_Knott-Chemical Kinetics - Simple Binding F + G to and from B
The study of this reaction, F + G goes to and from B, is common in chemistry and biochemistry. For example, F could be a hormone or drug and G the associated receptor sites.
binding
reaction
chemical kinetics
deterministic
Biochem Labs
probabilistic
kinetic reaction
Potential Scenario
170
views
63
downloads
0
comments
2013-Kose-Kunze-Climate Modeling in the Calculus and Differential Equations Classroom
We introduce here the basic principles of climate science for a one-dimensional Energy Balance Model (EBM),
climate change
Energy Balance Models
ice albedo
Potential Scenario
202
views
40
downloads
0
comments
2012-Campbell-EtAl-Parameter estimation in differential equation models with constrained states
We introduce a method to estimate parameters and states from a differential equation model while enforcing interpretability constraints such as monotone or non‐negative states.
chemical engineering
smoothing-based relaxation method
Potential Scenario
240
views
81
downloads
0
comments
2012-Bech-EtAl-Resources For Engineering Applications Of Math
Illustrations of applied mathematics including statics, truss, heat equation, column analysis, coupled oscillators, feedback control, AC circuit, chemical reactions, kinetics.
kinetics
heat equation
column analysis
coupled oscillators
feedback control
AC circuit
chemical reactions
Potential Scenario
139
views
90
downloads
0
comments
2010-Roberto_Munoz-Alicea-Mathematical Model for Enzyme Kinetics-Multiple Timescales Analysis
We study a basic model for enzyme substrate reaction. Through several assumptions and via nondimensionalization, we simplify the equations.
kinetics
Enzyme
substrate
nondimensionalization
multiple timescales
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