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    Technique Narrative
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    9-001-SkinBurnModelNumericalMethods-TechniqueNarrative
    The heat equation is an important partial differential equation (PDE) which describes the distribution of heat in a given region over time. Numerical methods play an important role in solving these.
    Maternal-Fetal interfaceheat equationConservation of Energytheat fluxEuler's forward methodcentral differenceskin burnhyperthermiathermal conductivitylayers
    Modeling Scenario
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    1-024-MalariaControl-ModelingScenario
    This project offers students a chance to make policy recommendations based on the analysis of models using both linear (exponential decay) and non-linear (logistic growth) differential equations.
    population dynamicsmalariaPolicyDecision-makingEuler's methodpharmacokineticsmosquitoimproved Euler's methodHuen's methodUS Army
    Potential Scenario
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    2001-Smith-Moore-The SIR Model for Spread of Disease
    A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.
    epidemicSIR modelEuler's methodherd immunityHong Kong flu
    Potential Scenario
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    2010-Keesom-EtAl-Fishing for Answers Investigating Sustainable Harvesting Ra
    The purpose of this report is to determine and propose a model by which an optimal harvesting frequency can be determined to maintain a steady population of Alaskan salmon.
    fisheriesEuler's methodnonlinearlogistic harvestingcanabalismsalmon
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
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    2015-Zhang-EtAl-On the Selection of ODE Models with Application to Predator-Prey Dynamical Models
    We propose a computationally inexpensive approach that employs statistical estimation of the full model, followed by a combination of a least squares approximation (LSA) and the adaptive Lasso.
    least-squares approximationSpline modelingMonte Carlo simulationsvariable selectionadaptive LASSO
    Potential Scenario
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    2018-Adeniji-EtAl-InverseProblemHolling-TannerModel
    We consider the inverse problem of parameter identification of nonlinear system of ODEs for a specific case of complete information about solution of the Holling-Tanner model for finite number of points for the finite time interval.
    goal functionabsolute error curvesinvers methodholling-Tanner model
    Potential Scenario
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    2009-Peter-Howard-Modeling With ODE
    This is a set of class notes rich in examples and ideas for modeling. There is some MatLab code in support of some of the activities.
    ratescompetitionpopulationepidemicpendulumcarbon datingreaction chemistrymechanicsplanetary motiondrag racingHamilton’s methodvariational method
    Potential Scenario
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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Potential Scenario
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    2018-Joseph-EtAl-A Nonlinear differential equation model of Asthma effect of environmental pollution using LHAM
    In this paper, we investigated a nonlinear differential equation mathematical model to study the spread of asthma in the environmental pollutants from industry and mainly from tobacco smoke from smokers in different type of population.
    asthmatobacco smokeLiao’s Homotopy analysis Method (environmental pollutants
    Potential Scenario
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    2017-Jean-Roux-Mathematical Models in Air Quality Problems
    Presents many models with analysis in air quality control. Starts with chemical kinetics models and builds complexity to PDE models.
    air pollution effects on forest ecosystemsfinite volume methodboundary layerchemical kineticsfinite differenceemissionsdepositionsadvection
    Potential Scenario
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    2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
    Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.
    cancertumor-inhibiting cytotoxic actiontumor-promoting inflammationimmune-induced tumor dormancytumor growth dynamics
    Potential Scenario
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    1987-Claude-Marmasse-Studies on differential equations of enzyme kinetics-Biomolecular scheme
    The integral curve is compared with the solutions given by the two classical approximations to the problem: it is shown that the steady-state approximation is to be preferred to the rapid equilibrium theory as a general method.
    steady-state modelisoclinesenzyme kinetics
    Potential Scenario
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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
    glucose tolerance testsum of squared residualsmultiple shooting methodcost function
    Modeling Scenario
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    6-068-VisualizingPredator-PreyCycles
    In this modeling scenario, we propose a gentle introduction to limit cycles using nullcline analysis and a spreadsheet graphical approach via the fourth-order Runge-Kutta method. We will be offering three predator-prey models, each more complex...
    nullclinespredator-preyGeometrypredatorRunge-Kuttapreylimit cycle
    Potential Scenario
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    2011-Gaff-Lenhart-Use of optimal control models to predict treatment time for managing tick-borne disease
    Tick-borne diseases have been on the rise recently, and correspondingly, there is an increased interest in implementing control measures to decrease the risk. Optimal control provides an ideal tool to identify the best method for reducing risk.
    diseaseoptimal controlTICKtick modeehrlichiosisbang bang control
    Modeling Scenario
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    1-037-CommonColdSpread-ModelingScenario
    This modeling scenario guides students to simulate and investigate the spread of the common cold in a residence hall. An example floor plan is given, but the reader is encouraged to use a more relevant example.
    diseasecommon coldresidence hall
    Potential Scenario
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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
    sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search
    Potential Scenario
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    2018-Akman-EtAl-Parameter Estimation in Ordinary Differential Equations Modeling via Particle Swarm Optimization
    We demonstrate Particle Swarm Optimization efficacy by showing that it outstrips evolutionary computing methods previously used to analyze an epidemic model.
    epidemicParticle Swarm Optimizationoptimize parameters
    Potential Scenario
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    2010-Roberto_Munoz-Alicea-Mathematical Model for Enzyme Kinetics-Multiple Timescales Analysis
    We study a basic model for enzyme substrate reaction. Through several assumptions and via nondimensionalization, we simplify the equations.
    kineticsEnzymesubstratenondimensionalizationmultiple timescales