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    Potential Scenario
    144

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
    longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics
    Potential Scenario
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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.
    infectionHIVT cells
    Potential Scenario
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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time delay.
    virusT cellsHopf bifurcationendemic equilibrium
    Article or Presentation
    130

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    2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
    Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without delays.
    delayHIV-1T cellscombination antiviral therapy
    Potential Scenario
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    2014-Bozkurt-Peker-Mathematical modelling of HIV epidemic and stability analysis
    A nonlinear mathematical model of differential equations with piecewise constant arguments is proposed. This model is analyzed by using the theory of both differential and difference equations to show the spread of HIV in a homogeneous population.
    diseaselogisticHIVpiecewise constantIndia
    Potential Scenario
    150

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    104

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    2017-Fred_Adler-Mathematically Modeling Asthma
    Our Asthma models have examined how a viral infection can tip the immune system into a different state, with the potential to predispose an individual to future asthma
    infectionasthmaimmune responserhinovirus
    Potential Scenario
    141

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Potential Scenario
    215

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    43

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    2012-Michael_Kerckhove-From Population Dynamics to Partial Differential Equations
    This article illustrates PDE models for location-dependent carrying capacities, migrations, and the dispersion of a population.
    population dynamicslogistic equationlocation-dependent carrying capacities
    Potential Scenario
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    2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
    Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.
    cancertumor-inhibiting cytotoxic actiontumor-promoting inflammationimmune-induced tumor dormancytumor growth dynamics
    Potential Scenario
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    71

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    2006-Shigui_Ruan-Delay differential equations in single species dynamics
    In this survey, we shall review various delay differential equations models arising from studying single species dynamics.
    allee_effectdelayed biological systemsfood limitperiodiciityrecruitment modelRegulation of Haematopoiesis
    Potential Scenario
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    53

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    2016-Banks-EtAl-Modeling Bumble Bee Population Dynamics with Delay Differential Equations
    To provide a tool for projecting and testing sensitivity of growth of populations under contrasting and combined pressures, we propose a delay differential equation model that describes multi-colony bumble bee population dynamics.
    population modelReproductionspline approximationsBombus terrestrisneonicotinoidsbumble bee
    Potential Scenario
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    2007-I-Liang_Chern-Mathematical Modeling and Differential Equations
    In this course, I will mainly focus on, but not limited to, two important classes of mathematical models by ordinary differential equations: • population dynamics in biology • dynamics in classical mechanics.
    population dynamicsecologydynamicsclassical mechanicschemical reaction
    Potential Scenario
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    2009-Marten-EtAl-Derivation and analysis of an ordinary differential equation for epilepsy dynamics
    In this paper we describe how an ordinary differential equation model of corticothalamic interactions may be obtained from a more general system of delay differential equations.
    delayepilepsy dynamicsepilepsybistabilityseizure activity
    Free Online Textbook
    166

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    2014-Andre_De Ross-Modeling Population Dynamics
    This course is intended as an introduction to the formulation, analysis and application of mathematical models that describe the dynamics of biological populations.
    predator-preycompetitionpopulationgrowthbifrucationtext
    Modeling Scenario
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    1-135-FishHarvesting-ModelingScenario
    This short activity will walk students through a guided list of questions to help them to understand how the stability of equilibrium changes with changes in a model parameter, in this case the rate of harvesting fish.
    population dynamicsfishstabilitybifurcationharvest
    Modeling Scenario
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    131

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    6-017-OncolyticViruses-ModelingScenario
    Students explore oncolytic virotherapy using systems of differential equations and numerical simulations.
    cancercancer-immune dynamicsimmune suppressor drugoncolytic virusvirotherapy
    Potential Scenario
    148

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    2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
    We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the time course of an individual’s infection.
    stabilityresistancevirusdrugepidemic competitionimmune responserhinovirus
    Potential Scenario
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    2014-Murillo-EtAl-Vertical Transmission in a Two-Strain Model of Dengue Fever
    The model is used to show that lower transmission rates of DENV-2 Asian are sufficient for displacing DENV-2 American in the presence of vertical transmission.
    Peruvector-host modeldengueepidemmiologyvertical transmission
    Potential Scenario
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    2013-Fathalla_Rihan-Delay Differential Equations in Biosciences - Parameter estimation and sensitivity analysis
    This is a review article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological phenomena such dynamical diseases and cell growth...
    epidemiologysensitivityImmunologyphysiologyRK-methodstime-lags
    Potential Scenario
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    2006-Ousmane_Mousa_Tessa-Mathematical model for control of measles by vaccination
    In this article, we use a compartmental mathematical model of the dynamics of measles spread within a population with variable size to provide this framework.
    vaccinationcompartmentherd immunitymeaslesoptimal strategy