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    Potential Scenario
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    2015-Beier-EtAl-Building Context with Tumor Growth Modeling Projects in Differential Equations
    Here we present two projects related to tumor growth appropriate for a first course in differential equations. They illustrate the use of problem-based learning to reinforce and extend course content via a writing or research experience.
    tummor growthresearch experience
    Potential Scenario
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    2020-Stepien_Kostelich_Kuang-Mathematics Cancer An Undergraduate Bridge Course in Applied Mathematics
    Most undergraduates have limited experience with mathematical modeling. This paper describes a course on the mathematical models of cancer growth and treatment.
    differential equationsmodelingundergraduate educationcancertumor
    Modeling Scenario
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    6-029-TumorGrowth-ModelingScenario
    This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of tumor growth over time.
    Pop_Growth Pilotlogisticcomparmenttumorsynthetic datasum of squares error
    Potential Scenario
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    2020-Cline-EtAl-A Vision for Projects Across the Mathematics Curriculum
    We describe a model that incorporates projects at all stages across the undergraduate mathematics curriculum. Finally, we provide samples of projects that we have used in selected courses.
    projectstechnical writinginterdisciplinary skills
    Free Online Textbook
    467

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    2012-Brian_Ingalls-Mathematical Modelling in Systems Biology An Introduction
    This is a comprehensive text with much biology background to motivate the mathematical modeling, exercises and answers, and many rich examples.
    spatialsensitivity analysisgene regulatory networksstochasticbifurcationmetabolic networkselectrophysiologytransductionrate lawsbiochemical reactions
    Modeling Scenario
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    1-062-BacteriaGrowth-ModelingScenario
    We offer students a simulation experience or data from a simulation and ask them to model the simulation using several approaches: exponential growth fit, difference equation, differential equation, and parameter estimation using EXCEL spreadsheet.
    bacteriaexponentialgrowth
    Potential Scenario
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    1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
    Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
    LSDcompartmentpharmacokinetics
    Potential Scenario
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    2016-Lewnard-Townsend-Climatic and evolutionary drivers of phase shifts in the plague epidemics of colonial India
    Our analysis shows that historical datasets can yield powerful insights into the transmission dynamics of reemerging disease agents with which we have limited contemporary experience to guide quantitative modeling and inference.
    infectious diseasepVector-Borne Diseaselagueplague
    Potential Scenario
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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.
    SASsuperpositionpharmacokineticscompartmental modelsmultiple dose
    Modeling Scenario
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    1-143-PopulationModelVariationsMATLAB-ModelingScenario
    Students will walk through a detailed derivation and review of basic population models (exponential and logistic) to create and understand variations of those models.
    population dynamicsecologylogistic growthbifurcation theoryslope fieldsextinctionharvestingqualitative analysisstocking
    Potential Scenario
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    2016-Lofgren-EtAl-Equations of the End Teaching Mathematical Modeling Using the Zombie Apocalypse
    In this article, we explore several uses of zombie epidemics to make mathematical modeling and infectious disease epidemiology more accessible to public health professionals, students, and the general public.
    simulationinfectious diseasediseaseepidemicZombieWhite Zed
    Potential Scenario
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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
    Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol
    Potential Scenario
    219

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    2012-Greer-Palin-Students in Differential Equations and Epidemiology Model a Campus Outbreak of pH1N1
    We describe a semester-long collaboration between a mathematics class and a biology class. Students worked together to understand and model the trajectory of the pandemic H1N1, pH1N1, outbreak across campus in fall 2009.
    H1N1pandemicspreadoutbreakpH1N1
    Modeling Scenario
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    1-030-EyeModel-ModelingScenario
    We offer a mathematical modeling experience using differential equations to model the volume of an intraocular gas bubble used by ophthalmologists to aid the healing of a surgically repaired region of the retina.
    retinal surgeryAkaike Information CriterionSpanishsum of square errorssurgeryretionaophthalmologyeyeintraocular gas bubble
    Modeling Scenario
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    1-098-NeuronDetection-ModelingScenario
    Students study a linear, first order, one-dimensional ordinary differential equation (ODE) and learn how it can help understand basics of neural dynamics. The modeling framework is known in mathematical neuroscience as ``integrate-and-fire''...
    biologyneuroscienceneuron physiologyvoltageintegrate and firethrefholscoincidence detectionRC circuit
    Potential Scenario
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    2019-Dimopulos-Heaney-Bukaida-IceCoverageInTheArcticClimateOverTime
    Through extensive research, it was found that the region’s oldest and thickest ice on this extent has significantly and continually decreased over the years.
    Antarctic foodd websBiodiversity declineice coveragepolar bear
    Potential Scenario
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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
    glucose tolerance testsum of squared residualsmultiple shooting methodcost function
    Modeling Scenario
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    6-045-CholeraTranmission-ModelingScenario
    During the project described here, the students will learn how to solve and address a practical problem such as cholera transmission using various mathematical tools.
    infectious diseasecholeraendemicdisease-freetransmission ratewaterborne pathogen
    Potential Scenario
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    2006-Wilensky-Reisman-Thinking Like a Wolf a Sheep or a Firefly
    We describe a computation-based approach that enables students to investigate the connections between different biological levels using agent-based, embodied modeling tools.
    simulationNetLogopredator-preyagent-basedwolffox
    Modeling Scenario
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    1-160-HeartDeathRate-ModelingScenario
    Students simulate experience from a given data set which represents the heart death rate during the period 2000 - 2010 using several approaches to include exponential decay, difference equation, differential equation, and parameter estimation...
    dataheart death rate