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    Potential Scenario
    144

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    2012-Gilbert_Koch-Modeling of Pharmacokinetic and Pharmacodynamics of Cancer and Arthritis
    In this work we develop preclinical PKPD models based on fundamental biological and pharmacological principles. Equipped with a PKPD model, different dosing schedules could be simulated.
    cancerpharmacodynamicsPKPD modelarthritisPharmacokineticanticancer
    Potential Scenario
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    48

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    2012-Nokkaew-EtAl-Estimation of Algae Growth Model Parameters by a Double Layer Genetic Algorithm
    This paper presents a double layer genetic algorithm (DLGA) to improve performance of the information-constrained parameter estimations.
    optimizationalgae growthgenetic algorithmssimulated dataconvergence of parameters
    Modeling Scenario
    265

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    126

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    1-084-GoingViral-ModelingScenario
    Students employ randomization in order to create a simulation of the spread of a viral disease in a population (the classroom). Students then use qualitative analysis of the expected behavior of the virus to devise a logistic differential equation.
    simulationlogisticrandomfittingpartial fractions
    Potential Scenario
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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
    glucose tolerance testsum of squared residualsmultiple shooting methodcost function
    Potential Scenario
    148

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    57

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    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    immune systemyellow fevercomputational immunologycomputational vaccinology
    Potential Scenario
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    84

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    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    Immunologyimmune systemAntigenvaccinologyyellow fever
    Potential Scenario
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    2008-Ribbing-EtAl-Mathematical models of diabetes progression
    Writing a good model for diabetes progression is difficult because the long time span of the disease makes experimental verification of modeling hypotheses extremely awkward. underlying the
    physiologyclinical trialsdiabetesdiabetes progression
    Potential Scenario
    132

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    77

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    General Resource
    203

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    48

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    2003-Knorrenschild-Gross-Text Books on Mathematical Modeling in Biology
    Text Books on Mathematical Modeling in Biology Compiled from the Internet by Michael Knorrenschild,
    biologyMathematical Biologytextbooktext
    Potential Scenario
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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
    metabolic syndromecompartment modelcholesterolhigh blood cholesterol
    Modeling Scenario
    314

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    37

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    1-018-LogisticPopModel-ModelingScenario
    We offer artificial (toy) and historical data on limited growth population situations in the study of protozoa and lead students through several approaches to estimating parameters and determining the validity of the logistic model in these...
    data analysisparameter estimationlogisticCiliate protozoapopulationlimited growthparameciaGause
    Modeling Scenario
    231

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    185

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    1-125-DiceyPopulation-ModelingScenario
    We offer students an opportunity to generate data for their team on a death and immigration model using 12 and 20 sided dice and then pass on the data to another student team for analysis with a model they built. The key is to recover the...
    simulationimmigrationdeathdice
    Modeling Scenario
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    629

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    6-001-Epidemic-ModelingScenario
    This paper presents real-world data, a problem statement, and discussion of a common approach to modeling that data, including student responses. In particular, we provide time-series data on the number of boys bedridden due to an outbreak of...
    datadifference equationsparameter estimationcontinuousepidemicdiscreteboarding school
    Article or Presentation
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    529

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    2020-TeachingModule-ModelingNonlethalInfluenzaEpidemic
    We discuss the modeling efforts and tools for success in modeling the spread of nonlethal influenza in an English boarding school
    moduleepidemicboarding schoolTeaching Module
    Potential Scenario
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    88

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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer cells.
    cancertumorfittingagent-based
    Modeling Scenario
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    501

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    1

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    1-017-DiseaseSpread-ModelingScenario
    Using a grid and m&m candies, we simulate the spread of disease. Students conduct the simulation and collect data to estimate parameters (in several ways) in a differential equation model for the spread of the disease.
    Modeling Scenario
    308

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    291

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    1-110-TidePoolSnails-ModelingScenario
    Students use linear differential equations to model temperature change, in a sand tide pool and inside the shell of a snail in the tide pool. We offer data on temperature in a tide pool as the sun heats the water. Students model the tide pool's...
    datasnailstemperatureNewton's Law of CoolingcoolingNewtonwarmingtital pooltide pool
    Potential Scenario
    191

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    64

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    1988-EY_Rodin-N_Taber-Yeast Growth Modelling in a Laboratory
    Modeling simple growth with some missing data and doing linear regression for parameter estimation in closed form solution of differential equation model and data.
    regressionyeastgrowth
    Potential Scenario
    190

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    45

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    2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
    This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
    Saccharomyces cerevisiaelogisticyeastdeathgrowthsugaralcohol
    Modeling Scenario
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    407

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    1-102-CancerTumor-ModelingScenario
    This module guides students in the use of differential equation models to predict cancer growth and optimize treatment outcomes. Several classical models for cancer growth are studied, including exponential, power law, Bertalanffy, logistic, and...
    optimizationlogisticpredictiondata fittingpower lawGompertzcancer growtheponentialBertalanaffy