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    Potential Scenario
    283

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    73

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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Modeling Scenario
    211

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    242

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Modeling Scenario
    478

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    196

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
    wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue
    Potential Scenario
    146

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    59

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model
    Potential Scenario
    155

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    52

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    2004-Jones-Song-Thomas-Controlling wound healing through debridement
    In this article, a system of differential equations that models slough/wound interaction is developed.
    bacteriawound healinghealingderidingisocline
    Potential Scenario
    145

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    85

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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
    metabolic syndromecompartment modelcholesterolhigh blood cholesterol
    Potential Scenario
    132

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    77

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    Potential Scenario
    203

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    92

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    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
    mathematical modeldataLSDMetabolismbloodstreamlysergic acid diethylamidedistribution
    Potential Scenario
    1249

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    47

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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Potential Scenario
    186

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    74

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    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng
    Article or Presentation
    170

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    88

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    2015-European_Bioinformatics_Institute-Bio-Models-Database
    Bio Models Database is a repository of computational models of biological processes. Models described from literature are manually curated and enriched with cross-references. All models are provided in the Public Domain.
    biologydatabasebioinformaticsModelscomputational models
    Potential Scenario
    169

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    68

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    2003-Richard-Carson-Tracer kinetic modeling in PET
    The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with modern instrumentation are key components to successful developments in PET.
    Metabolismtomographyradiopharmaceuticalspositron emission
    Modeling Scenario
    337

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    537

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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    nullclinespharmacokineticsdigoxindrug eliminationtwo compartment
    Potential Scenario
    217

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    98

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    2001-Smith-Moore-The SIR Model for Spread of Disease
    A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.
    epidemicSIR modelEuler's methodherd immunityHong Kong flu
    Potential Scenario
    179

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    44

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    2007-Hui_Luo-Population Modeling by Differential Equations
    A general model for the population of Tibetan antelope is constructed. The present model shows that the given data is reasonably logistic.
    population dynamicsextinctionlogisticTibetan antelope
    Potential Scenario
    218

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    85

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    2014-XM-Huang-Ordinary Differential Equation Model and its Application in the Prediction Control of Population
    In this paper, we study two kinds of ordinary differential equation models, i.e., Malthus model and Logistic model, and discuss their applications in the prediction control of population.
    population dynamicsLogistic modelMalthus ModelPopulation Prediction Control
    Potential Scenario
    135

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    40

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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time delay.
    virusT cellsHopf bifurcationendemic equilibrium
    Potential Scenario
    235

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    68

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.
    population dynamicsLotka-Volterragrowth ratemutualismLichen
    Potential Scenario
    150

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    57

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    1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
    A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
    compartment modelpharmacokineticsnonlinear estimationone compartment model
    Potential Scenario
    227

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    77

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    2014-Vance-Eads-Sensitivity Analysis of a Three-Species Nonlinear Response Omnivory Model with Predator Stage Structure
    We investigate a three-species nonlinear response omnivory model incorporating stage structure in the top predator. The model consists of four coupled ordinary differential equations involving fourteen parameters.
    stage structuresensitivity analysismortalityomnivoreomnivory modelsearch rates