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    Potential Scenario
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    2005-P_Howard-Modeling with ODE
    In these notes we consider three critical aspects in the theory of ordinary differential equations: developing models of physical phenomena, mathematically well-posed, solving ODE numerically .
    Fluid Mechanicscompartmentpopulationsvariational methodsHamiltonian mechanics
    Potential Scenario
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    2013-Fathalla_Rihan-Delay Differential Equations in Biosciences - Parameter estimation and sensitivity analysis
    This is a review article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological phenomena such dynamical diseases and cell growth...
    epidemiologysensitivityImmunologyphysiologyRK-methodstime-lags
    Potential Scenario
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    2009-Peter-Howard-Modeling With ODE
    This is a set of class notes rich in examples and ideas for modeling. There is some MatLab code in support of some of the activities.
    ratescompetitionpopulationepidemicpendulumcarbon datingreaction chemistrymechanicsplanetary motiondrag racingHamilton’s methodvariational method
    Potential Scenario
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    2011-Carl_Leinbach-Beyond Newton's law of cooling - estimation of time since death
    The paper offers an excellent history of temperature-based methods and then proceeds to demonstrate these with some data. Here the history is rich and will support student investigation as well as faculty development.
    time of deathNewton's aw of cooling
    Potential Scenario
    206

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium, biomass transfer, pesticides, forecasting prices,...
    chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade
    Technique Narrative
    402

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    206

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    9-001-SkinBurnModelNumericalMethods-TechniqueNarrative
    The heat equation is an important partial differential equation (PDE) which describes the distribution of heat in a given region over time. Numerical methods play an important role in solving these.
    Maternal-Fetal interfaceheat equationConservation of Energytheat fluxEuler's forward methodcentral differenceskin burnhyperthermiathermal conductivitylayers
    Potential Scenario
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    2007-Bellomo-De_Angelis-Delitala-Lecture Notes on Mathematical Modelling in Applied Sciences
    The Lectures Notes correspond to the first part of the course devoted to modelling issues to show how the application of models to describe real world phenomena generates mathematical problems to be solved by appropriate mathematical methods.
    spring massLegendre polynomialsintegro-differential equationskinetic theory
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
    sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search
    Potential Scenario
    202

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Potential Scenario
    170

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    2018-Akman-EtAl-Parameter Estimation in Ordinary Differential Equations Modeling via Particle Swarm Optimization
    We demonstrate Particle Swarm Optimization efficacy by showing that it outstrips evolutionary computing methods previously used to analyze an epidemic model.
    epidemicParticle Swarm Optimizationoptimize parameters
    Potential Scenario
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    1999-T_Chen-HL_He-GM_Church-S_Shafer-Modeling Gene Expression with Differential Equations
    The paper proposes and give great detail for a differential equation model for gene expression with two methods for constructing the model from a set of temporal data.
    gene expressiongenekineticgene translationgene transcription
    Potential Scenario
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    1992-John_Mathews-Bounded population growth-a curve fitting lesson
    The purpose of this article is to present two methods for fitting the logistic curve to data supplied by the U. S. census bureau.
    datalogisticlinearizationfitting
    Modeling Scenario
    409

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    282

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    1-024-MalariaControl-ModelingScenario
    This project offers students a chance to make policy recommendations based on the analysis of models using both linear (exponential decay) and non-linear (logistic growth) differential equations.
    population dynamicsmalariaPolicyDecision-makingEuler's methodpharmacokineticsmosquitoimproved Euler's methodHuen's methodUS Army
    Potential Scenario
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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters particularly suited to situations where noise levels are...
    time seriesEvaluation SPLINEgeneleast squaresbifurcation
    Potential Scenario
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    79

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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub
    Free Online Textbook
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    2014-Jeffrey_Chasnov-Lecture_Notes_on_Introduction_to_Differential_Equations
    The differential equations text is 128 pages and develops and motivates the theory of the material nicely, with links to YouTube lectures to assist.
    differential equationsbiologytextbook
    Modeling Scenario
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    6-004-VillageEpidemic-ModelingScenario
    Students are offered data from a plague epidemic that occurred in the middle of the seventeenth century in Eyam, a small English village. With only two assumptions offered to students they are to build a mathematical model.
    SIR modelsepidemicsusceptibleinfectiveremovedEyamEnglish village
    Modeling Scenario
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    10-100-InsectOutbreaks-ModelingScenario
    We use a system of difference equations that incorporates a temperature-dependent MPB population growth rate to model the outbreak and recovery cycle in mountain pine beetle-infested forests.
    ecologyclimate changeinsectinsect outbreaksinsect outbreaksolitary wave
    Potential Scenario
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    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.
    Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate