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    Potential Scenario
    162

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    84

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.
    SASsuperpositionpharmacokineticscompartmental modelsmultiple dose
    Potential Scenario
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    1976-JG-Wagner-Computers in pharmacokinetics
    This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.
    kineticscomputerparametersPharmacologydrugspharmacokinetics
    Potential Scenario
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    93

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    2018-David_Bourne-Pharmacokinetics – Source Material
    This is a rich source of pharmacokinetics modeling activities and data. These are syllabus notes with homework assignments listed.
    boluspharmacokineticspharmacodynamicdrug distribution
    Potential Scenario
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    1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
    Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.
    pPharmacologypharmacokineticslidocaine
    Potential Scenario
    209

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    93

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.
    cancertumor modelingangiogenesistumor growthpatient care
    Potential Scenario
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    50

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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time
    Potential Scenario
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    54

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    2009-Noakes-Sleigh-Mathematical models for assessing the role of airflow on the risk of airborne infection in hospital wards
    Understanding the risk of airborne transmission can provide important information for designing safe healthcare environments with an appropriate level of environmental control for mitigating risks.
    infectioncompartmenthospitalventilationairbornesthochasticWells–Riley
    Potential Scenario
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    90

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    2010-Roberto_Munoz-Alicea-Mathematical Model for Enzyme Kinetics-Multiple Timescales Analysis
    We study a basic model for enzyme substrate reaction. Through several assumptions and via nondimensionalization, we simplify the equations.
    kineticsEnzymesubstratenondimensionalizationmultiple timescales
    Potential Scenario
    199

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    64

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    2011-Brian_Winkel-Parameter Estimates in Differential Equation Models for Population Growth
    We estimate the parameters present in several differential equation models of population growth, specifically logistic growth models and multiple species competition models.
    logisticpopulationparameciaGausegradient search
    Potential Scenario
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    2001-Smith-Moore-The SIR Model for Spread of Disease
    A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.
    epidemicSIR modelEuler's methodherd immunityHong Kong flu
    Article or Presentation
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    47

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    2011-Brian_Winkel-Parameter_Estimates_in_Differential_Equation_Models_for_Population_Growth
    We estimate the parameters present in several differential equation models of population growth, specifically single species exponential and logistic growth, and multiple species competition and predation models.
    population modelparameter estimationpopulationparameter
    Potential Scenario
    168

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    71

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    2011-Yanyu_Xiao-Study of Malaria Transmission Dynamics by Mathematical Models
    The novelty lies in the fact that different distribution functions are used to describe the variance of individual latencies. The theoretical results of this project indicate that latencies reduce the basic reproduction number.
    infectious diseaseinfectionmalarialatencyspatial dispersalmulti-species
    Potential Scenario
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    48

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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
    glucose tolerance testsum of squared residualsmultiple shooting methodcost function
    Potential Scenario
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    72

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium, biomass transfer, pesticides, forecasting prices,...
    chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade
    Modeling Scenario
    309

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    125

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    5-036-HalfCarVibration-ModelingScenario
    Vibration vehicle models provide an opportunity to integrate vehicle-based vibrations into a mechanical engineering vibrations course. The project is on a multiple-degree-of-freedom (MDOF) including pitch and bounce of vehicle body on suspension...
    vibrationvehiclehalf-car modelfinite element analysisshock absorberssuspension
    Potential Scenario
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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Modeling Scenario
    256

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    227

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    1-054-GrowthInFarmland-ModelingScenario
    An enriching project developing a model from data with missing temporal information is described. Students fit functions to the data that leads to the creation of a differential equations model, which they then are required to analyze in multiple...
    fittingfarmfarmland
    Modeling Scenario
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    1-063-ThreeHoleColumnOfWater-ModelingScenario
    We consider a column of water with three holes or spigots through which water can exit and ask students to model the height of the column of water over time.
    fallingcolumn of waterTorricelli's Lawmultiple spigotsspigots
    Modeling Scenario
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    1-118-SolowEconomicGrowth-ModelingScenario
    Students construct and analyze the celebrated Solow-Swan model of economic growth theory. The project is divided into three sequential parts to teach students to understand, develop, and analyze a simple nonlinear model of economic dynamics.
    optimizationeconomicssteady stategrowthSolow-Swan modelcapitalproductionlaborGolden Rule of Economic Growth
    Modeling Scenario
    242

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    4-020-AnIEDBlast-ModelingScenario
    These three exercises offer students a chance to model with second order ordinary differential equations, how they might incorporate a spring-mass system into a larger model, and how they can use the model to determine the results of a dynamical...
    applied mathematicsforcesFree Body DiagramImprovised Explosive Devicessum of forces