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Date
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Potential Scenario
123
views
39
downloads
0
comments
2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
absorption
Michaelis-Menten
Metabolism
drug metabolism
circulation
Potential Scenario
128
views
52
downloads
0
comments
1984-Marguerite_Hays-Compartmental Models for Human Iodine Metabolism
Compartmental models for the various aspects of human iodine metabolism are reviewed, emphasizing the role of Mones Berman in the development of this field.
compartment model
iodine
thyroid
Potential Scenario
176
views
59
downloads
0
comments
1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
mathematical model
data
LSD
Metabolism
bloodstream
lysergic acid diethylamide
distribution
Potential Scenario
101
views
38
downloads
0
comments
2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
glucose tolerance test
sum of squared residuals
multiple shooting method
cost function
Potential Scenario
152
views
60
downloads
0
comments
1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
LSD
compartment
pharmacokinetics
Potential Scenario
146
views
49
downloads
0
comments
2003-Richard-Carson-Tracer kinetic modeling in PET
The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with modern instrumentation are key components to successful developments in PET.
Metabolism
tomography
radiopharmaceuticals
positron emission
Potential Scenario
114
views
36
downloads
0
comments
2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
liverworts
intraveneous
pharmacokinetics
ethanol
ethanol infustion
pharmacodynamic
tissue model
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