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Downloads
Views
Date
Relevance
Potential Scenario
103
views
38
downloads
0
comments
2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.
Michaelis-Menten
Enzyme
substrate
compartment
pharmacokinetics
rate constant
urinary data
absorption rate
Potential Scenario
182
views
50
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Potential Scenario
145
views
46
downloads
0
comments
2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
paracetamol
pharmacokinetics
stomach
small intestine
sulfapyridine
Potential Scenario
150
views
50
downloads
0
comments
2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
absorption
Michaelis-Menten
Metabolism
drug metabolism
circulation
Potential Scenario
134
views
52
downloads
0
comments
2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
QUBES Leadership Team
parameters
absorption
bifurcation
pharmacokinetics
calcium
cognitive decline
Potential Scenario
208
views
89
downloads
0
comments
1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
LSD
compartment
pharmacokinetics
Modeling Scenario
1181
views
5494
downloads
0
comments
5-001-LSD-ModelingScenario
We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
LSD
Spanish
compartment
pharmacokinetics
lysergic acid diethylamide
Potential Scenario
133
views
56
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
141
views
80
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Modeling Scenario
210
views
242
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Modeling Scenario
306
views
282
downloads
0
comments
1-114-EarthClimate-ModelingScenario
In this modeling scenario, we investigate the Earth's climate using a zero-dimensional energy balance model. Energy balance models are climate models that try to predict the average surface temperature of the Earth.
climate
energy
temperature
linearization
phase lines
energy balance model
root finding
Potential Scenario
149
views
45
downloads
0
comments
2010-Singh-Mishra-athematical modeling approach to study growth rate of grassroots technological innovations
In this paper we have proposed a simple mathematical model by using ordinary differential equation to know the spread rate of technological innovations in rural India.
logistic
exponential
sigmoid
technological innovations
asymptotic
spread of innovation
Potential Scenario
256
views
60
downloads
0
comments
1989-EY_Rodin-K_Egan-Mathematics modelling of the rate of chemical reactions
The development of improved designs for chemical reactors as well as the prediction of optimal operating conditions in chemical production are based on an understanding of the rates at which chemical processes occur.
kinetics
first order
reaction
second order
zeroth order
Modeling Scenario
213
views
715
downloads
0
comments
1-124-WorldPopulation-ModelingScenario
We build models of world population using data to estimate growth rate.
population dynamics
human
growth rate
varying growth rate
Modeling Scenario
382
views
302
downloads
0
comments
1-026-Evaporation-ModelingScenario
We provide data on evaporation of 91% isopropyl alcohol in six different Petri dishes and one conical funnel and on evaporation of water in one Petri dish. We ask students to develop a mathematical model for the rate of change in the respective...
evaporation
cone
alcohol
Petri dish
Modeling Scenario
651
views
398
downloads
0
comments
5-011-ModelingIbuprofren-ModelingScenario
We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
data
AIC
Akaike Information Criterion
absorption
sum of square errors
compartment model
ibuprofen
delay
Potential Scenario
250
views
40
downloads
0
comments
2009-Das-EtAl-Bioeconomic harvesting of a pre-predator fishery
This paper deals with the problem of non-selective harvesting of a prey–predator system by using a reasonable catch-rate function instead of usual catch-per-unit-effort hypothesis.
predator-prey
harvesting
Pontryagin’s maximum principle
bioeconomic
bionomic equilibrium
biotechnical productivity
catch-rate function
optimal equilibrium
Potential Scenario
185
views
69
downloads
0
comments
2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages of expected future short rates.
finance
interest rate
bond yield
macroeconomics
Potential Scenario
201
views
90
downloads
0
comments
1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
mathematical model
data
LSD
Metabolism
bloodstream
lysergic acid diethylamide
distribution
Modeling Scenario
371
views
334
downloads
0
comments
7-040-TankInterruptMixing-ModelingScenario
We present a first order differential equation model for the interrupted mixing of a tank with salt water. We offer two solution strategies (1) two step approach and (2) Laplace Transforms.
Laplace transform
inverse Laplace Transform
salt
tank
mixing
interrupt
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