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    Potential Scenario
    155

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    87

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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer cells.
    cancertumorfittingagent-based
    Modeling Scenario
    236

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    592

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    9-020-HeatDiffusion-ModelingScenario
    This project guides students through experimental, analytical, and numerical techniques for understanding the heat (diffusion) equation with nonhomogeneous boundary conditions. In particular, students collect data and model a physical scenario.
    laboratoryDiffusionheat
    Potential Scenario
    182

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    49

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.
    experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates
    Potential Scenario
    160

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    71

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    1935 GFGause Article Predator Prey Oscillations
    N/A
    Lotka-Volterrapredatorparameciumpreycycleoscillate
    Potential Scenario
    212

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    66

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    2007-Helfgott-Seier-Some Mathematical and Statistical Aspects of Enzyme Kinetics
    We will analyze some basic ideas behind enzyme kinetics, which allow us to deal with separable and linear differential equations as well as realize the need to use power series.
    kineticsEnzymeexperimental dataregresion
    Potential Scenario
    201

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    73

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Modeling Scenario
    333

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    459

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    0

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    3-099-PullBack-ModelingScenario
    We guide students through the development of an empirical model for the velocity and distance traveled of a simple pull-back toy. Students can record videos and extract data using their own pull-back toy or use data included.
    dynamicspull-back toy
    Potential Scenario
    216

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    46

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    0

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    1980-Peastrel-Lynch-Armenti-Terminal velocity of a shuttlecock in vertical fall
    We have performed a straightforward vertical fall experiment for a case where the effects of air resistance are important and directly measurable.
    fallingterminal velocityshuttlecockvertical fall
    Modeling Scenario
    221

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    243

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    3-069-HeatInBar-ModelingScenario
    The temperature distribution along a uniform slender bar due to conduction and convection is investigated through experimental, analytical, and numerical approaches.
    heat transferexperimentconductionconvectionboundary conditionsfinite volume method
    Potential Scenario
    168

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    47

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    2006-Matt_MacWilliams-Developing ODEs to Describe the Motion of a Paper Helicopter
    This paper attempts to create a model that describes the motion of a paper helicopter using engineering, physical and statistical knowledge.
    experimental designhelicopter
    Potential Scenario
    202

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    74

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    0

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    1997-Jeff_Graham-Julia_Barnes-A Laboratory Experience for Students of Differential Equations Using RLC Circuits
    Acknowleging that applied mathematics courses rarely offer any hand-on experiences the authors constructed an RLC circuit from which they collected data and validated the differential equation of the RLC circuit.
    datacollectionslaboratorycircuitRLC
    Modeling Scenario
    223

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    259

    downloads

    0

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    6-029-TumorGrowth-ModelingScenario
    This modeling scenario guides a student familiar with single ordinary differential equation (ODE) models towards the development of a more complex system of two ODEs for describing the evolution of tumor growth over time.
    Pop_Growth Pilotlogisticcomparmenttumorsynthetic datasum of squares error
    Modeling Scenario
    429

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    119

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    0

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    6-067-LotkaVolterra-ModelingScenario
    This modeling scenario guides students through the process of fitting the Lotka-Volterra model of two differential equations to a real time series observational data. Students use the capabilities of R and R studio.
    time seriesdatacompetitionLotka-Volterramodel fittingpredictiongauseRexperimental
    Modeling Scenario
    366

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    590

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    0

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    3-103-PullBackCars-ModelingScenario
    This activity offers analysis of a toy pull-back car: solution of a differential equation from model; data collection and parameter estimation; and adapting the model to predict maximum speed and distance traveled for a new pull-back distance.
    modelingdynamicshands-ontoypull-back carpullback
    Modeling Scenario
    1181

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    5494

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    5-001-LSD-ModelingScenario
    We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
    LSDSpanishcompartmentpharmacokineticslysergic acid diethylamide
    Potential Scenario
    130

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    48

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    2010-Shianga-EtAl-Computational model of the human glucose-insulin regulatory system
    A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The
    glucose tolerance testsum of squared residualsmultiple shooting methodcost function
    Potential Scenario
    156

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    59

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    2006-G_Ashline-J_Ellis-Monaghan-How high-fast-long-Modeling water rocket flight with calculus
    We describe an easy and fun project using water rockets to demonstrate applications of single variable calculus concepts.
    calculusFlightprojectilewater rocket
    Potential Scenario
    202

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    59

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    2003-Yildirim-Mackey-Feedback Regulation in the Lactose Operon
    A mathematical model for the regulation of induction in the lac operon in Escherichia coli is presented.
    mRNAlactoselactose operonfeedback regulation
    Article or Presentation
    166

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    53

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    1980-Peastrel-Lynch-Armenti-Terminal_velocity_of_a_shuttlecock_in_vertical_fall
    This paper offers a set of data on a falling shuttlecock (the moving object in badminton) in air. How the authors collected the data is described fully and can be replicated easily by modern equipment.
    parameter estimationdata collectionresistancefallingterminal velocityNewton's Second Law of Motionshuttlecock
    Potential Scenario
    148

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    57

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    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    immune systemyellow fevercomputational immunologycomputational vaccinology