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    Potential Scenario
    162

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    83

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.
    SASsuperpositionpharmacokineticscompartmental modelsmultiple dose
    Potential Scenario
    305

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    54

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    1976-JG-Wagner-Computers in pharmacokinetics
    This is a seminal paper in pharmacokinetics in which the author introduces historic notions and approaches. As can be seen from the abstract there is a variety of material here.
    kineticscomputerparametersPharmacologydrugspharmacokinetics
    Potential Scenario
    254

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    91

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    2018-David_Bourne-Pharmacokinetics – Source Material
    This is a rich source of pharmacokinetics modeling activities and data. These are syllabus notes with homework assignments listed.
    boluspharmacokineticspharmacodynamicdrug distribution
    Potential Scenario
    164

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    43

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    1971-Boyes-Scott-Jebson-Godman-Julian-Lidocaine in Man
    Plasma levels of lidocaine were measured in 5 normal male volunteers following both intravenous and oral administration of the drug.
    pPharmacologypharmacokineticslidocaine
    Potential Scenario
    209

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    93

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    2014-Enderling-Chaplain-Mathematical Modeling of Tumor Growth and Treatment
    Herein we describe fundamentals of mathematical modeling of tumor growth and tumor-host interactions, and summarize some of the seminal and most prominent approaches.
    cancertumor modelingangiogenesistumor growthpatient care
    Potential Scenario
    182

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    50

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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time
    Potential Scenario
    151

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    53

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    2009-Noakes-Sleigh-Mathematical models for assessing the role of airflow on the risk of airborne infection in hospital wards
    Understanding the risk of airborne transmission can provide important information for designing safe healthcare environments with an appropriate level of environmental control for mitigating risks.
    infectioncompartmenthospitalventilationairbornesthochasticWells–Riley
    Potential Scenario
    139

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    90

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    2010-Roberto_Munoz-Alicea-Mathematical Model for Enzyme Kinetics-Multiple Timescales Analysis
    We study a basic model for enzyme substrate reaction. Through several assumptions and via nondimensionalization, we simplify the equations.
    kineticsEnzymesubstratenondimensionalizationmultiple timescales
    Article or Presentation
    182

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    45

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    2011-Brian_Winkel-Parameter_Estimates_in_Differential_Equation_Models_for_Population_Growth
    We estimate the parameters present in several differential equation models of population growth, specifically single species exponential and logistic growth, and multiple species competition and predation models.
    population modelparameter estimationpopulationparameter
    Potential Scenario
    166

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    70

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    2011-Yanyu_Xiao-Study of Malaria Transmission Dynamics by Mathematical Models
    The novelty lies in the fact that different distribution functions are used to describe the variance of individual latencies. The theoretical results of this project indicate that latencies reduce the basic reproduction number.
    infectious diseaseinfectionmalarialatencyspatial dispersalmulti-species
    Potential Scenario
    203

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    72

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium, biomass transfer, pesticides, forecasting prices,...
    chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade
    Modeling Scenario
    308

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    125

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    5-036-HalfCarVibration-ModelingScenario
    Vibration vehicle models provide an opportunity to integrate vehicle-based vibrations into a mechanical engineering vibrations course. The project is on a multiple-degree-of-freedom (MDOF) including pitch and bounce of vehicle body on suspension...
    vibrationvehiclehalf-car modelfinite element analysisshock absorberssuspension
    Potential Scenario
    136

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    80

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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Modeling Scenario
    264

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    215

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    6-010-SocialCampaign-ModelingScenario
    The epidemic modeling problem is formulated as a system of three nonlinear, first order differential equations in which three compartments (S, I, and R) of the population are linked.
    diseasegrowth rateJudgment and Decision MakingSIR modelinfections diseasesocial campaignrecovery ratedelay timejoining processquitting processexponential distribution
    Potential Scenario
    209

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    66

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    2007-Helfgott-Seier-Some Mathematical and Statistical Aspects of Enzyme Kinetics
    We will analyze some basic ideas behind enzyme kinetics, which allow us to deal with separable and linear differential equations as well as realize the need to use power series.
    kineticsEnzymeexperimental dataregresion
    Potential Scenario
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    71

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    2006-Shigui_Ruan-Delay differential equations in single species dynamics
    In this survey, we shall review various delay differential equations models arising from studying single species dynamics.
    allee_effectdelayed biological systemsfood limitperiodiciityrecruitment modelRegulation of Haematopoiesis
    Potential Scenario
    276

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    75

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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub
    Potential Scenario
    138

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    58

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    1994-Paul_Davis-Asking Good Questions about Differential Equations
    A general essay about the Rule of Three – numerical, algebraic, and graphical perspectives + modeling with one illustration about Irish population.
    questionspopulationnumericalphysical contextgraphicalalgebraicIreland
    Potential Scenario
    214

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    69

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    2019-Ekici_Plyley. Inquiry-Based_Modeling_of_Population_Dynamics_With_Logistic_Differential_and_Difference_Equations
    Inquiry-based learning activities on modeling and controlling the growth of locally relevant species, such as lionfish or sea turtles, are developed by the authors.
    population dynamicslogisticInquiry-based modelingIBL
    Technique Narrative
    373

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    197

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    1-030-RandomPerturbation-TechniqueNarrative
    After a brief historical view of this problem, we will demonstrate the derivation of first order linear differential equations with random perturbations.
    random perturbationBrownian motionLangevin equationRiemann-Steiltjes integralWiener processIto's calculus