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    Potential Scenario
    155

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    1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
    Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
    fishCell Membraneflowbloodbladdercountercurrent
    Potential Scenario
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    38

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    2012-José_Sérgio_Domingues-Gompertz Model - Resolution and Analysis for Tumors
    The main objective of this paper is to use the Gompertz equation in order to study the development of blood irrigated solid tumors, using parameters defined in some important bibliographic references about the mathematical modelling of tumors.
    tumorGompertz equationgrowth tumor
    Potential Scenario
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    1977-Michael_Mackey-Leon_Glass-Oscillation and Chaos in Physiological Control Systems
    First-order nonlinear differential-delay equations describing physiological control systems are studied. The equations display a broad diversity of dynamical behavior including limit cycle oscillation.
    sensitivitychaosparametersRespirationdelayblood cells
    Potential Scenario
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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
    metabolic syndromecompartment modelcholesterolhigh blood cholesterol
    Potential Scenario
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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    Potential Scenario
    176

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    72

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    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng
    Potential Scenario
    139

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    87

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    2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
    We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.
    metabolic syndromecompartmentcholesteroltwo-compartment modelcholesterol transport
    Potential Scenario
    128

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    38

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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time delay.
    virusT cellsHopf bifurcationendemic equilibrium
    Potential Scenario
    233

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    55

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    2011-Radouane_Yafia-A Study of Differential Equations Modeling Malignant Tumor Cells in Competition with Immune System
    In this paper, we present a competition model of malignant tumor growth that includes the immune system response. The model considers two populations: immune system (effector cells) and population of tumor (tumor cells).
    Immunologytumorhopf bifrucation
    Potential Scenario
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    1986-Istvan_Gyori-Connections between compartment systems pipes and integro-differential equations
    In this paper we give the mathematical description of models in which the mass transport between compartments requires a given definite time or transit times are distributed according to given probability distribution functions.
    physiologypipelinecompartmentbloodcirculationintegro-differential equation
    Potential Scenario
    165

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    65

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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.
    infectionHIVT cells
    Article or Presentation
    125

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    33

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    2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
    Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without delays.
    delayHIV-1T cellscombination antiviral therapy
    Potential Scenario
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    2007-Exben_Friis-Jensen-Modeling and Simulation of Glucose-Insulin Metabolism
    In this thesis one of the models of diabetes, Bergman’s minimal model is described trough derivation and simulations.
    Metabolisminsulin resistanceglucosePID controllerintolerance
    Potential Scenario
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    51

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Potential Scenario
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    50

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    2018-Winkle-Igoshin-Bennett-Josic-Ott-Modeling_Mechanical_Interactions_in_Growing_Populations_of_Rod-Shaped_Bacteria
    Here, we present an agent-based model that allows growing cells to detect and respond to mechanical interactions.
    bacteriaagent-basedpopulationbrod-shapedcellular growth
    Potential Scenario
    132

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    77

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    2015-Khan-EtAl-How differential equations influence the tumor growth via mathematical models
    This work demonstrates the importance of differential equations to develop mathematical model of tumor growth.
    tumorcancdercancerous cellsimmunotherapymalignant
    Potential Scenario
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    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
    anesthesiapharmacokineticspharmacodynamicanesthetic
    Potential Scenario
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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Potential Scenario
    142

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    55

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    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    immune systemyellow fevercomputational immunologycomputational vaccinology
    Potential Scenario
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    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    Immunologyimmune systemAntigenvaccinologyyellow fever