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    Technique Narrative
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    9-001-SkinBurnModelNumericalMethods-TechniqueNarrative
    The heat equation is an important partial differential equation (PDE) which describes the distribution of heat in a given region over time. Numerical methods play an important role in solving these.
    Maternal-Fetal interfaceheat equationConservation of Energytheat fluxEuler's forward methodcentral differenceskin burnhyperthermiathermal conductivitylayers
    Modeling Scenario
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    1-024-MalariaControl-ModelingScenario
    This project offers students a chance to make policy recommendations based on the analysis of models using both linear (exponential decay) and non-linear (logistic growth) differential equations.
    population dynamicsmalariaPolicyDecision-makingEuler's methodpharmacokineticsmosquitoimproved Euler's methodHuen's methodUS Army
    Modeling Scenario
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    6-002-EulerCromerPendulum-ModelingScenario
    This activity introduces students to the concept of numerical stability. While modeling a simple pendulum, students compare performance of the semi-implicit Euler-Cromer method with Euler's method and the higher-order Improved Euleror algorithm.
    pendulumsemi-implicit methodsEuler-Cromernumerical solvers
    Technique Narrative
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    5-005-StiffDifferentialEquations-TechniqueNarrative
    This material introduces the topic of ``stiffness'' for a system of ordinary differential equations (ODE's), through a series of examples. Stiffness is a property that a system of ODE's may posses that make it difficult to solve numerically.
    Euler's methodexplicit methodsimplicit methodsstiffsitffnessstiff differential equationinstability
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
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    2012-Campbell-EtAl-Parameter estimation in differential equation models with constrained states
    We introduce a method to estimate parameters and states from a differential equation model while enforcing interpretability constraints such as monotone or non‐negative states.
    chemical engineeringsmoothing-based relaxation method
    Potential Scenario
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    2003-Givens-Bonfima-Direct observation of normal modes in coupled oscillators
    We propose a simple and inexpensive method to directly observe each normal mode of a system of coupled oscillators, as well as to measure its corresponding frequency, without performing Fourier analysis or using expensive apparatus.
    frequencyresonancecoupled oscillator
    Potential Scenario
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    2018-Adeniji-EtAl-InverseProblemHolling-TannerModel
    We consider the inverse problem of parameter identification of nonlinear system of ODEs for a specific case of complete information about solution of the Holling-Tanner model for finite number of points for the finite time interval.
    goal functionabsolute error curvesinvers methodholling-Tanner model
    Potential Scenario
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    2016-Roberto_Camporesi-A fresh look at linear ordinary differential equations with constant coefficients
    We present an approach to the impulsive response method for solving linear constant-coefficient ordinary differential equations of any order based on the factorization of the differential operator.
    impulseGreen functionsinstructional exposition
    Potential Scenario
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    2009-Peter-Howard-Modeling With ODE
    This is a set of class notes rich in examples and ideas for modeling. There is some MatLab code in support of some of the activities.
    ratescompetitionpopulationepidemicpendulumcarbon datingreaction chemistrymechanicsplanetary motiondrag racingHamilton’s methodvariational method
    Potential Scenario
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    2014-Wang-EtAl-Estimating Mixed-Effects Differential Equation Models
    When multiple replicates of measurements are available for the dynamic process, it is of great interest to estimate mixed-effects in the ODE model for the process. We propose a semiparametric method to estimate mixed-effects ODE models.
    pharmacokineticsdynamic modelssmoothingsplinemixed-effects modelsHiV combination therapy
    Potential Scenario
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    2017-Jean-Roux-Mathematical Models in Air Quality Problems
    Presents many models with analysis in air quality control. Starts with chemical kinetics models and builds complexity to PDE models.
    air pollution effects on forest ecosystemsfinite volume methodboundary layerchemical kineticsfinite differenceemissionsdepositionsadvection
    Potential Scenario
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    2016-Wilkie-EtAl-Using ODEs to Explore Cancer-Immune Dynamics and Tumor Dormancy
    Here we present a general method using ordinary differential equations (ODEs) to model and analyze cancer-immune interactions, and in particular, immune-induced tumor dormancy.
    cancertumor-inhibiting cytotoxic actiontumor-promoting inflammationimmune-induced tumor dormancytumor growth dynamics
    Technique Narrative
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    1-002-IntegratingFactor-TechniqueNarrative
    We develop a strategy to solve first order differential equations by transforming one side of the equation to the derivative of a product of two functions, thereby making it easy to antidifferentiate that side.
    Integrating Factor
    Potential Scenario
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    2019-Stender_EtAl-Recovery_Of_Differential_Equations_From_Impulse_Response
    In this work, a recent method, which allows reconstructing differential equations from time series data, is extended for higher degrees of automation.
    time seriesregressionresponseimpulseoscillationsignal processingsparse regressionsystem identification
    Technique Narrative
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    1-001-SepartionOfVariables-TechniqueNarrative
    We discuss strategies to solve first order, ordinary differential equations with mathematical models when the variables may be separated.
    solutionsstrategymethodapplications
    Modeling Scenario
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    6-068-VisualizingPredator-PreyCycles
    In this modeling scenario, we propose a gentle introduction to limit cycles using nullcline analysis and a spreadsheet graphical approach via the fourth-order Runge-Kutta method. We will be offering three predator-prey models, each more complex...
    nullclinespredator-preyGeometrypredatorRunge-Kuttapreylimit cycle
    Potential Scenario
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    2011-Gaff-Lenhart-Use of optimal control models to predict treatment time for managing tick-borne disease
    Tick-borne diseases have been on the rise recently, and correspondingly, there is an increased interest in implementing control measures to decrease the risk. Optimal control provides an ideal tool to identify the best method for reducing risk.
    diseaseoptimal controlTICKtick modeehrlichiosisbang bang control
    Potential Scenario
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    2003-Rasmussen-Keynes-Lines of Eigenvectors and Solutions to Systems of Linear Differential Equations
    The purpose of this paper is to describe an instructional sequence where students invent a method for locating lines of eigenvectors and corresponding solutions to systems of two first order linear ordinary differential equations with constant...
    instructional designeigenvalueseigenvalue analysis
    Potential Scenario
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    2003-Bohren-Dimensional analysis-falling bodies--fine art of not solving differential equations
    Dimensional analysis is a simple, physically transparent and intuitive method for obtaining approximate solutions to physics problems, especially in mechanics.
    falling bodydimensional analysisdrag