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2018-David_Bourne-Pharmacokinetics – Source Material

This is a rich source of pharmacokinetics modeling activities and data. These are syllabus notes with homework assignments listed.

boluspharmacokineticspharmacodynamicdrug distribution

Modeling Scenario

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1-085-DrugBolus-ModelingScenario

Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?

concentrationsum of square errorsbolusdrugrate constantadminister

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2018-David_Bourne-Pharmacokinetics – Source Material

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