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    Potential Scenario
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    Potential Scenario
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    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
    Potential Scenario
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    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    Potential Scenario
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    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    Potential Scenario
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    1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
    Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
    Modeling Scenario
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    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    Modeling Scenario
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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    Potential Scenario
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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    Modeling Scenario
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    1-085-DrugBolus-ModelingScenario
    Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
    Modeling Scenario
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    3-061-ChemEngApps-ModelingScenario
    Students go through a chemical engineering problem: calculate concentration profile of cyclohexane within a catalyst pellet by solving a second order linear differential equation; then analyze the concentration as the radius of the catalyst...
    Potential Scenario
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    1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
    Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We model this.
    Modeling Scenario
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    1-138-InnerEarDrugDelivery-ModelingScenario
    Students examine local drug delivery to the cochlea. The delivery system is modeled as a liquid mixing problem. Students formulate the differential equation, and solve the equation using separation of variables or integrating factor.
    Potential Scenario
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    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    Modeling Scenario
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    5-030-AirshedSulphur-ModelingScenario
    Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for analysis to predict long-term levels of levels of...
    Potential Scenario
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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    Modeling Scenario
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    3-051-ProjectileMotions-ModelingScenario
    We consider several instances of projectile flight without resistance, one on level ground and one from edge of cliff to determine maximum distance and placement.
    Modeling Scenario
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    3-052-OptimalProjectileFiring-ModelingScenario
    We offer the opportunity to model a projectile's trajectory in several cases, all without resistance.
    Potential Scenario
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    1972-R_C_Rothermel-A Mathematical Model for Predicting Fire Spread in Wildland Fuels
    The development of a mathematical model for predicting rate of fire spread and intensity applicable to a wide range of wildland fuels is presented from the conceptual stage through evaluation and demonstration of results to hypothetical fuel models.
    Potential Scenario
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    2011-Mandal-EtAl-Mathematical models of malaria
    The first aim of this article is to develop, starting from the basic models, a hierarchical structure of a range of deterministic models of different levels of complexity. The second is to elaborate, using some of the representative mathematical...
    Potential Scenario
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