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Date
Relevance
Potential Scenario
135
views
79
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Potential Scenario
192
views
68
downloads
0
comments
2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
anesthesia
pharmacokinetics
pharmacodynamic
anesthetic
Potential Scenario
129
views
55
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
177
views
49
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Potential Scenario
155
views
45
downloads
0
comments
1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
fish
Cell Membrane
flow
blood
bladder
countercurrent
Modeling Scenario
293
views
106
downloads
0
comments
1-131-CaffeineElimination-ModelingScenario
We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
caffeine
elimination
pharmacokinetics
drug
Modeling Scenario
327
views
521
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Potential Scenario
274
views
68
downloads
0
comments
1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
LSD
correlation coefficient
compartment model
lysergic acid diethylamide
performance
test score
tissue concentration
Modeling Scenario
303
views
219
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Modeling Scenario
900
views
1171
downloads
0
comments
3-061-ChemEngApps-ModelingScenario
Students go through a chemical engineering problem: calculate concentration profile of cyclohexane within a catalyst pellet by solving a second order linear differential equation; then analyze the concentration as the radius of the catalyst...
Spanish
porous medium
catalyisis
cyclohexene
hydrogel
dehydrogenation
hyperbolic trig functions
Potential Scenario
166
views
63
downloads
0
comments
1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We model this.
LSD
score
plasma
lysergic acid diethylamide
human subjuects
Modeling Scenario
398
views
273
downloads
0
comments
1-138-InnerEarDrugDelivery-ModelingScenario
Students examine local drug delivery to the cochlea. The delivery system is modeled as a liquid mixing problem. Students formulate the differential equation, and solve the equation using separation of variables or integrating factor.
concentration
drug delivery
inner ear
cochlea
hearing loss
Potential Scenario
268
views
74
downloads
0
comments
2014-Blomhøj-EtAl-Compartment models
An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
concentration
kinetics
physiology
compartment
salt
tank
balance
reactions
mink
bathtub
Modeling Scenario
295
views
149
downloads
0
comments
5-030-AirshedSulphur-ModelingScenario
Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for analysis to predict long-term levels of levels of...
sulphur
pollution
airshed
hydrogen sulfide
sulfur dioxide
Potential Scenario
139
views
57
downloads
0
comments
2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
liverworts
intraveneous
pharmacokinetics
ethanol
ethanol infustion
pharmacodynamic
tissue model
Modeling Scenario
1077
views
169
downloads
0
comments
3-051-ProjectileMotions-ModelingScenario
We consider several instances of projectile flight without resistance, one on level ground and one from edge of cliff to determine maximum distance and placement.
trajectory
launching radiant
projectile motion
projectile
no resistance
angle of launch
Modeling Scenario
172
views
55
downloads
0
comments
3-052-OptimalProjectileFiring-ModelingScenario
We offer the opportunity to model a projectile's trajectory in several cases, all without resistance.
projectile motion
projectile
launch angle
maximum range
Potential Scenario
148
views
64
downloads
0
comments
1972-R_C_Rothermel-A Mathematical Model for Predicting Fire Spread in Wildland Fuels
The development of a mathematical model for predicting rate of fire spread and intensity applicable to a wide range of wildland fuels is presented from the conceptual stage through evaluation and demonstration of results to hypothetical fuel models.
prediction
forest fire
fire management
fire spread
fuel
Potential Scenario
181
views
58
downloads
0
comments
2011-Mandal-EtAl-Mathematical models of malaria
The first aim of this article is to develop, starting from the basic models, a hierarchical structure of a range of deterministic models of different levels of complexity. The second is to elaborate, using some of the representative mathematical...
epidemiology
transmission
host-parasite
malaria
Ross model
Potential Scenario
108
views
59
downloads
0
comments
2015-Peter_Cumber-Waggling pendulums and visualization in mechanics
This article describes an equation of motion for a waggling pendulum.
resonance
inverted pendulum
mechanics
damped pendulum
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