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    Potential Scenario
    109

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    2012-Transtrum-Qiu-Optimal experiment selection for parameter estimation in biological differential equation models
    We explore the question to what extent parameters can be efficiently estimated by appropriate experimental selection.
    experimental designsystems biologyAssociation & Data Fittingreaction ratesdecay rates
    Modeling Scenario
    159

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    293

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    3-060-DataToDifferentialEquation-ModelingScenario
    Students use knowledge of second-order linear differential equations in conjunction with physical intuition of spring-mass systems to estimate the damping coefficient and spring constant from data.
    Association & Data Fittingmassspring-mass systemspring\total distancenumerical differentiation
    Potential Scenario
    104

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    48

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    1992-John_Mathews-Bounded population growth-a curve fitting lesson
    The purpose of this article is to present two methods for fitting the logistic curve to data supplied by the U. S. census bureau.
    datalogisticlinearizationfitting
    Potential Scenario
    116

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    47

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    2018-Dyjuan_Tatro-The_Mathematics_of_Cancer-Fitting_Gompertz_Equation_to_Tumor_Growth
    Fitting the Gompertz Model to long term breast cancer study data, this project ascertains gompertzian parameters that can be used to predicts tumor growth as a function of time.
    tumorgrowthGompertzfittingparameter
    Modeling Scenario
    348

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    95

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    6-067-LotkaVolterra-ModelingScenario
    This modeling scenario guides students through the process of fitting the Lotka-Volterra model of two differential equations to a real time series observational data. Students use the capabilities of R and R studio.
    time seriesdatacompetitionLotka-Volterramodel fittingpredictiongauseRexperimental
    Potential Scenario
    117

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    35

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    2009-Su-EtAl-Fitting Compartmental Models to Multiple Dose Pharmacokinetic Data using SAS
    In the case of a multiple dose study where subjects experience different dosing times, a superposition principle can be used to recursively account for each additional dose.
    SASsuperpositionpharmacokineticscompartmental modelsmultiple dose
    Potential Scenario
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    2015-Heiko_Enderling-Integrating experimental data to calibrate quantitative cancer models
    For quantitative cancer models to be meaningful and interpretable the number of unknown parameters must be kept minimal. We focus on a tumor hierarchy of cancer stem and progenitor non-stem cancer cells.
    cancertumorfittingagent-based
    Potential Scenario
    130

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    35

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    2019-Hu-Treinen-One-step_method_for_modelling_longitudinal_data_with_differential_equations
    This study proposes a new approach to estimate the parameters in differential equation models used to describe non-linear trajectories of longitudinal data.
    simulationparameter estimationshoppingfittingbehaviour
    Potential Scenario
    141

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    52

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    2017-D_Goulet-Modeling, Simulating, and Parameter Fitting of Biochemical Kinetic Experiments
    In many chemical and biological applications, systems of differential equations containing unknown parameters are used to explain empirical observations and experimental data. The differential equations are typically nonlinear.
    optimizationBiochemistrysensitivity analysischromatographymass actioncluster analysisconservation lawsdimerizationestrogen receptor protein
    Modeling Scenario
    265

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    236

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    1-102-CancerTumor-ModelingScenario
    This module guides students in the use of differential equation models to predict cancer growth and optimize treatment outcomes. Several classical models for cancer growth are studied, including exponential, power law, Bertalanffy, logistic, and...
    optimizationlogisticpredictiondata fittingpower lawGompertzcancer growtheponentialBertalanaffy
    Potential Scenario
    86

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    37

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    2008-Brewer-EtAl-Fitting ordinary differential equations to short time course data
    In this paper, we present a survey of existing algorithms and describe the main approaches. We also introduce and evaluate a new efficient technique for estimating ODEs linear in parameters particularly suited to situations where noise levels are...
    time seriesEvaluation SPLINEgeneleast squaresbifurcation
    Modeling Scenario
    271

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    218

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    1-102C-CancerGrowth-ModelingScenario
    This module guides students in the use of differential equation models to predict cancer growth and study treatment outcomes. Several classical models for cancer growth are presented including exponential, power law, Bertalanffy, logistic, and...
    optimizationcancerlogisticexponentialpredictiontumorgrowthdata fittingpower lawBertanffyGompertz
    Modeling Scenario
    204

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    186

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    1-054-GrowthInFarmland-ModelingScenario
    An enriching project developing a model from data with missing temporal information is described. Students fit functions to the data that leads to the creation of a differential equations model, which they then are required to analyze in multiple...
    fittingfarmfarmland
    Potential Scenario
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    64

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    2017-Floyd_Ballard-Dice Activities for DE Models
    This document includes descriptions of four activities that are appropriate for a calculus or differential equations class, all using dice to motivate a differential equation model for a real-world scenario.
    simulationcurve fittingcdicecollect dataclass activitiesanalyze dataclass activity
    Modeling Scenario
    318

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    172

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    1-005C-OilSlick-ModelingScenario
    We describe a modeling activity for Calculus I students in which modeling with difference and differential equations is appropriate.
    Problem Solvingoil slickspreadfittinglineassumptions
    Modeling Scenario
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    144

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    1-066-USCensusModeling-ModelingScenario
    The United States Census, conducted every 10 years, gives data on the United States population, that can be modeled with the exponential, logistic, or Gompertz functions.
    datalogisticpopulationGompertzcensusgoodness of fit
    Modeling Scenario
    357

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    392

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    1-011-Kinetics-ModelingScenario
    We make the connection between chemistry course and differential equations coursework. We do this through modeling kinetics, or rates of chemical reaction. We study zeroth, first, and second order reactions.
    kineticschemistryLaw of Mass Actionchemical kineticsorder of reactionchemical reaction
    Potential Scenario
    114

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    35

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    2010-Singh-Mishra-athematical modeling approach to study growth rate of grassroots technological innovations
    In this paper we have proposed a simple mathematical model by using ordinary differential equation to know the spread rate of technological innovations in rural India.
    logisticexponentialsigmoidtechnological innovationsasymptoticspread of innovation
    Modeling Scenario
    349

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    138

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    1-001s-StochasticMDeathImmigration-ModelingScenario
    We develop a mathematical model of a death and immigration process using m&ms as a stochastic process with the help of probability generating functions (pgf). We start with 50 m&ms in a bag.
    simulationdatalogisticimmigrationstochasticdeathfitting
    Modeling Scenario
    305

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    121

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    1-001d-HotelPopulationDecay-ModelingScenario
    You will be modeling the following situation: 100 people are in a hotel. Each day, each person has a random chance of 50% of leaving the hotel. No new people enter the hotel. Before you run the simulation in MATLAB, answer some questions.
    simulationlogisticexponential decayfitting