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    Modeling Scenario
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    1-141-MMGameRevisited-ModelingScenario
    It is assumed that the probability of an M&M chocolate, when tossed, falling on the M side is 0.5 The goal is to find a probability distribution of the probability q which is Pr(randomly chosen M&M falling M up when tossed).
    Probabilitystochastic processesBayesian methodsprobability distribution
    Potential Scenario
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    45

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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
    longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics
    Potential Scenario
    216

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    73

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    2008-Lawson-Marion-An Introduction to Mathematical Modelling
    This is a broad based set of notes with sections: Building Models, Studying Models, and Using Models. No depth on any model, no solution strategies, but good references to models, and general approaches that apply in most situations are offered.
    time serieslinear regressionAkaike Information Criterionmcomparision models
    Free Online Textbook
    408

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    108

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    2015-Eric_Sullivan-Numerical Methods_An_Inquiry-Based_Approach_with_Python
    This is an OER effort on the part of Eric Sullivan to explore the joy of numerical methods. He has provided several versions.
    pythonnumerical analysisNumerical Methods
    Technique Narrative
    399

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    195

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    2-001-NumericalMethodsComparisons-TechniqueNarrative
    This material teaches the basics of numerical methods for first order differential equations by following graphical and numerical approaches. We discuss the order of accuracy of the methods and compare their CPU times.
    Euler's methodimproved Euler's methodRK3 methodsRK4 methodsorder of accuracyabsolute errorCPU time
    Technique Narrative
    527

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    597

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    5-005-StiffDifferentialEquations-TechniqueNarrative
    This material introduces the topic of ``stiffness'' for a system of ordinary differential equations (ODE's), through a series of examples. Stiffness is a property that a system of ODE's may posses that make it difficult to solve numerically.
    Euler's methodexplicit methodsimplicit methodsstiffsitffnessstiff differential equationinstability
    Potential Scenario
    135

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    51

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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data interpretation and decision making.
    physiologyinverse problem
    Technique Narrative
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    348

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    1-060-RegularPerturbation-TechniqueNarrative
    This paper presents an introduction to a set of analytical approximations referred to as regular perturbation. This is a particular mathematical tool within the broader set of perturbation methods.
    perturbationregular perturbationasymptotic expansionsanalytical approximationBernoulli equation
    Free Online Textbook
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    2015-Dan_Sloughte-Notes on Diffy Qs Differential Equations for Engineers
    This is a calculus book with the last chapter devoted to ordinary differential equations topics. The effort begins with a study of numerical methods and goes through traditional technique strategies.
    Numerical Methodspendulumtext
    Potential Scenario
    294

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    47

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological processes.
    protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular
    Potential Scenario
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    45

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    2011-Carl_Leinbach-Beyond Newton's law of cooling - estimation of time since death
    The paper offers an excellent history of temperature-based methods and then proceeds to demonstrate these with some data. Here the history is rich and will support student investigation as well as faculty development.
    time of deathNewton's aw of cooling
    Potential Scenario
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    108

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    2005-Albert_Tarantola-Inverse Problem Theory and Methods for Model Parameter Estimation
    This is a bible of approaches to support parameter estimation approaches in inverse problems. Theory and algorithms are offers with examples.
    Algorithminverse probleminverse
    Potential Scenario
    203

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    72

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    2017-GR_Gustafson-Differential Equations Course Materials
    There are many applications from compartment and cascade analysis, recycling brine tank, home heating with multiple rooms, chemostat, microbes, heartbeats, lidocaine, nutrient flow in an aquarium, biomass transfer, pesticides, forecasting prices,...
    chemostatmicrobesbiomassforecastingtransfercompartmentpesticidesearthquaketankheatinglidocainebrineheartbeatsnutrient flowaquariumelectric networkscircuitsloggingbuildingcascade
    Potential Scenario
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    2013-Fathalla_Rihan-Delay Differential Equations in Biosciences - Parameter estimation and sensitivity analysis
    This is a review article to show that delay differential models have a richer mathematical framework (compared with models without memory or after-effects) and a better consistency with biological phenomena such dynamical diseases and cell growth...
    epidemiologysensitivityImmunologyphysiologyRK-methodstime-lags
    Free Online Textbook
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    70

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    2009-Eriksson- Estep-Hansho-Johnson-Computational Differential Equations
    Differential Equations and Advanced Computational Differential Equations, presents a unified approach to computational mathematical modeling using differential equations based on a principle of a fusion of mathematics and computation.
    Galerkin
    Free Online Textbook
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    63

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    2018-Mohammed_Kaabar-A_Friendly_Introduction_to_Differential_Equations
    In this book, there are five chapters: Laplace Transform, Systems of Homogeneous Linear Differential Equations, Methods of First and Higher Orders DEs, Extended Methods of First and Higher Orders DEs, and Applications of DEs.
    textbookordinary differential equations
    Technique Narrative
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    204

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    9-001-SkinBurnModelNumericalMethods-TechniqueNarrative
    The heat equation is an important partial differential equation (PDE) which describes the distribution of heat in a given region over time. Numerical methods play an important role in solving these.
    Maternal-Fetal interfaceheat equationConservation of Energytheat fluxEuler's forward methodcentral differenceskin burnhyperthermiathermal conductivitylayers
    Potential Scenario
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    2007-Bellomo-De_Angelis-Delitala-Lecture Notes on Mathematical Modelling in Applied Sciences
    The Lectures Notes correspond to the first part of the course devoted to modelling issues to show how the application of models to describe real world phenomena generates mathematical problems to be solved by appropriate mathematical methods.
    spring massLegendre polynomialsintegro-differential equationskinetic theory
    Potential Scenario
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    2017-Justin_Krueger-Parameter Estimation Methods for Ordinary Differential Equation Models with Applications to Microbiology
    We demonstrate the feasibility of principal differential analysis using simulation studies and then apply the method to intestinal and vaginal microbiota data.
    microbiologyLotka Volterrramicrobiota
    Potential Scenario
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    1999-Khorasheh-Ahmadi-Gerayeli-Application of Direct Search Optimization for Pharmacokinetic Parameter Estimation
    For simple pharmacokinetic compartmental models, analytical solution to the governing differential equations provide a mean to evaluate the associated rate constants. Such methods, however, can not be used used for more complex multi-compartment...
    sum of square errorsleast squarespharmacokineticslineteicscompartmental modelsdirect search