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Downloads
Views
Date
Relevance
Potential Scenario
174
views
50
downloads
0
comments
2012-Augustus-Wali-Mathematical Modeling of Uganda Population Growth
The purpose of this paper focuses on the application of logistic equation to model the population growth of Uganda using data from 1980 to 2010 (inclusive).
population growth
logistic growth
Drug and Alcohol detoxification
carrying capacity
vital coefficients
Potential Scenario
144
views
44
downloads
0
comments
2019-Lorelei_Koss-SIR_Models_Differential_Equations_that_Support_The_Common_Good
This article surveys how SIR models have been extended beyond investigations of biologically infectious diseases to other topics that contribute to social inequality and environmental concerns.
environment
SIR
social justice
epidemic
common good
Modeling Scenario
325
views
238
downloads
0
comments
1-026-Evaporation-ModelingScenario
We provide data on evaporation of 91% isopropyl alcohol in six different Petri dishes and one conical funnel and on evaporation of water in one Petri dish. We ask students to develop a mathematical model for the rate of change in the respective...
evaporation
cone
alcohol
Petri dish
Potential Scenario
166
views
43
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Potential Scenario
88
views
35
downloads
0
comments
2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.
Michaelis-Menten
Enzyme
substrate
compartment
pharmacokinetics
rate constant
urinary data
absorption rate
Modeling Scenario
257
views
156
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Modeling Scenario
271
views
208
downloads
0
comments
7-010-MultipleDoses-ModelingScenario
Two multiple dose drug administration regimens are offered. A drug is to maintain a certain level (above a set minimum and below a set maximum) in the blood stream and one regimen involves bolus injections and another involves steady drip flow...
drug discovery
step function
dose
Dirac
drug administration
inverse Laplace Transform
intraveneous
bolus
steady drip
Potential Scenario
112
views
59
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Modeling Scenario
193
views
103
downloads
0
comments
1-080-DrugAdministration-ModelingScenario
A simple drug administration situation is modeled with only two observations.
decay
bloodstream
drug
rate constant
administer
Potential Scenario
113
views
44
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
116
views
37
downloads
0
comments
2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
paracetamol
pharmacokinetics
stomach
small intestine
sulfapyridine
Modeling Scenario
277
views
147
downloads
0
comments
5-022-ColdPill-ModelingScenario
A model for the flow of a cold pill drug through the gastrointestinal compartment to the bloodstream compartment of a human subject is proposed. Students solve the system of differential equation model, use known parameter values, and plot solutions.
rates
medicine
drug discovery
compartment
cold pill
gastrointestinal
bloodstream
Potential Scenario
117
views
30
downloads
0
comments
2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical studyÂ
To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics with ARV therapy.
longitudinal data
AIDS
antiretroviral drug therapy
Bayesian nonlinear mixed-effects
time-varying drug efficacy
HIV dynamics
Potential Scenario
161
views
37
downloads
0
comments
2013-Alicia_Caldwell-Students Rise to the Challenge of Modeling Yeast Growth Despite Sour Hiccups from Imperfect Data
This paper describes a lab in which students in an Applied Mathematics in Biology course observe the growth of Saccharomyces cerevisiae, a yeast strain, in differing sugar concentrations for use in learning modeling.
Saccharomyces cerevisiae
logistic
yeast
death
growth
sugar
alcohol
Potential Scenario
173
views
53
downloads
0
comments
2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
anesthesia
pharmacokinetics
pharmacodynamic
anesthetic
Potential Scenario
132
views
39
downloads
0
comments
1999-Peter_Deuflhard-Differential Equations in Technology and Medicine
It deals with a variety of challenging real life problems selected from clinical cancer therapy, communication technology, polymer production, and pharmaceutical drug design.
cancer
design
tumor
drug
polymer
therapy
Potential Scenario
118
views
42
downloads
0
comments
2006-Loyd-Wodarz-Drug Resistance in Acute Viral Infections-Rhinovirus as a Case Study
We develop an epidemiological model that can be used to address the spread of resistance at the population level, and a virus dynamics model that can be used to study the dynamics of virus over the time course of an individual’s infection.
stability
resistance
virus
drug
epidemic competition
immune response
rhinovirus
Potential Scenario
126
views
39
downloads
0
comments
2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
absorption
Michaelis-Menten
Metabolism
drug metabolism
circulation
Modeling Scenario
300
views
407
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Modeling Scenario
181
views
48
downloads
0
comments
1-131-CaffeineElimination-ModelingScenario
We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
caffeine
elimination
pharmacokinetics
drug
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