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    Potential Scenario
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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time delay.
    virusT cellsHopf bifurcationendemic equilibrium
    Modeling Scenario
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    6-017-OncolyticViruses-ModelingScenario
    Students explore oncolytic virotherapy using systems of differential equations and numerical simulations.
    cancercancer-immune dynamicsimmune suppressor drugoncolytic virusvirotherapy
    Potential Scenario
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    2002-Nelson-Perelson-Mathematical analysis of delay differential equations models of HIV-1 infection
    We develop and analyze a set of models that include intracellular delays, combination antiretroviral therapy, and the dynamics of both infected and uninfected T cells.
    infectionHIVT cells
    Article or Presentation
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    2002-Patrick_Nelson-Alan_Perelson-Mathematical_analysis_of_delay_differential _equation_models_of_HIV-1_infection
    Models of HIV-1 infection that include intracellular delays are more accurate representations of the biology and change the estimated values of kinetic parameters when compared to models without delays.
    delayHIV-1T cellscombination antiviral therapy
    Potential Scenario
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    2017-Allali-EtAl-Mathematical Modeling of the Adaptive Immune Responses in the Early Stage of the HBV Infection
    The aim of this paper is to study the early stage of HBV infection and impact delay in the infection process on the adaptive immune response, which includes cytotoxic T-lymphocytes and antibodies.
    logisticHBV infectionadaptive immunie responseT-lymphocytes
    Potential Scenario
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    40

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    2017-Bonin-EtAl-Mathematical modeling based on ordinary differential equations - promising approach to vaccinology
    As a proof of concept, we developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    immune systemyellow fevercomputational immunologycomputational vaccinology
    Potential Scenario
    111

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    61

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    2016-Bonin-EtAl-Mathematical modeling based on ordinary differential equations-vaccinology
    We developed a model of the immune response to vaccination against the yellow fever. Our simulations have shown consistent results when compared with experimental data available in the literature.
    Immunologyimmune systemAntigenvaccinologyyellow fever
    Potential Scenario
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    2011-Radouane_Yafia-A Study of Differential Equations Modeling Malignant Tumor Cells in Competition with Immune System
    In this paper, we present a competition model of malignant tumor growth that includes the immune system response. The model considers two populations: immune system (effector cells) and population of tumor (tumor cells).
    Immunologytumorhopf bifrucation
    Potential Scenario
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    49

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    2011-W_Wood-Squigonometry
    The differential equations used to define a unit circle, namely x’(t) = - y(t), y’(t) = (t), x(0) = 1, y(0) = 0 are generalized to produce interesting functions which satisfy trig like identities.
    Trigonometric Functionscirclesquigonometryinverse functiontrigonmetry
    Potential Scenario
    118

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    25

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    2011-W_Wood-Squigonometry
    The differential equations used to define a unit circle, namely x’(t) = - y(t), y’(t) = x(t), x(0) = 1, y(0) = 0 are generalized to produce interesting functions which satisfy trig like identities.
    TrigonometryTrigonometric Functionsparametric equationscirclesinecosinesquigonometryinverse function
    Modeling Scenario
    175

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    102

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    1-009-ICUSpread-ModelingScenario
    We offer students the opportunity to model the percentage of voluntary nonprofit hospitals in the United States with Intensive Care Units during the period of 1958-1974.
    logisticsum of square errorsIntensive Care Unithospitalspread
    Potential Scenario
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    40

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    1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
    Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
    fishCell Membraneflowbloodbladdercountercurrent
    Modeling Scenario
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    113

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    3-015-StyrofoamBallFall-ModelingScenario
    We are given data on a falling Styrofoam ball and we seek to model this motion.
    footballresistancegravityfalling bodysum of square errorsNewton's Second Law of Motionsum of forcesstyrofoam
    Modeling Scenario
    175

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    114

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    5-025-SaltCompartments-ModelingScenario
    Model a phenomena in which salt mixtures from two tanks are mixed using several strategies.
    compartmentsalttanks
    Potential Scenario
    120

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    48

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    2018-Winkle-Igoshin-Bennett-Josic-Ott-Modeling_Mechanical_Interactions_in_Growing_Populations_of_Rod-Shaped_Bacteria
    Here, we present an agent-based model that allows growing cells to detect and respond to mechanical interactions.
    bacteriaagent-basedpopulationbrod-shapedcellular growth
    Modeling Scenario
    180

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    119

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    1-025-MixingItUp-ModelingScenario
    Students build three different models for levels of salt in a tank of water and at each stage the level of complexity increases with attention to nuances necessary for success.
    compartmentsalttankmixing
    Potential Scenario
    101

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    63

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    2015-Khan-EtAl-How differential equations influence the tumor growth via mathematical models
    This work demonstrates the importance of differential equations to develop mathematical model of tumor growth.
    tumorcancdercancerous cellsimmunotherapymalignant
    Modeling Scenario
    592

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    447

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    1-032-WordPropagation-ModelingScenario
    This activity is a gentle introduction to modeling via differential equations. The students will learn about exponential growth by modeling the rate at which the word jumbo has propagated through English language texts over time.
    Googleexponential growthlanguageword problemsetymologyNgrampropagationJumbo
    Modeling Scenario
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    7-008-MachineReplacement-ModelingScenario
    Students build an integro-differential equation model using a convolution for machine replacement strategies for two different machine failure models.
    Probabilityreplacement numberLaplace transformindustrial engineeringmachineconvolutiondistributiojstep functionderivative definition
    Article or Presentation
    87

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    43

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    1992-Emelie_Kenney-Differential_equations_and_the_AIDS_epidemic
    This paper describes a lecture for Calculus II students in which the Acquired Immune Deficiency Syndrome was used to motivate study of first-order linear differential equations and the derivative as a rate of change.
    datafirst orderparameterAIDS