Skip to Main Content
Powered by QUBES

Resources

Text Search:
Applied Filters
    Potential Scenario
    79

    views

    35

    downloads

    0

    comments

    2012-Shargel-Yu-AccessPharmacy-Applied Biopharmaceutics and Pharmacokinetics
    Step by step formation of drug absorption models is shown with many good graphics of system and plots. Solutions are offered but no solution methods are shown.
    Michaelis-MentenEnzymesubstratecompartmentpharmacokineticsrate constanturinary dataabsorption rate
    Potential Scenario
    155

    views

    41

    downloads

    0

    comments

    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time
    Potential Scenario
    108

    views

    37

    downloads

    0

    comments

    2005-Minna_Wedenberg-Pharmacokinetic modeling of gastric emptying
    The development of new drug substances is a complex, time consuming and expensive process. Reducing the time for drug development and avoiding late termination of candidate drugs are important challenges for the pharmaceutical industry.
    paracetamolpharmacokineticsstomachsmall intestinesulfapyridine
    Potential Scenario
    114

    views

    36

    downloads

    0

    comments

    2011-Nguyen-Shi-Modeling the absorption circulation and metabolism of tirapazamine
    This apparently is a student project and it develops the kinetic model, uses Matlab for numerical solution, analytic solution and numerical solution.
    absorptionMichaelis-MentenMetabolismdrug metabolismcirculation
    Potential Scenario
    102

    views

    42

    downloads

    0

    comments

    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Potential Scenario
    139

    views

    57

    downloads

    0

    comments

    1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
    Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
    LSDcompartmentpharmacokinetics
    Modeling Scenario
    1077

    views

    5234

    downloads

    0

    comments

    5-001-LSD-ModelingScenario
    We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
    LSDSpanishcompartmentpharmacokineticslysergic acid diethylamide
    Potential Scenario
    101

    views

    40

    downloads

    0

    comments

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics
    Potential Scenario
    98

    views

    55

    downloads

    0

    comments

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response
    Modeling Scenario
    164

    views

    181

    downloads

    0

    comments

    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Potential Scenario
    119

    views

    35

    downloads

    0

    comments

    2010-Singh-Mishra-athematical modeling approach to study growth rate of grassroots technological innovations
    In this paper we have proposed a simple mathematical model by using ordinary differential equation to know the spread rate of technological innovations in rural India.
    logisticexponentialsigmoidtechnological innovationsasymptoticspread of innovation
    Potential Scenario
    216

    views

    41

    downloads

    0

    comments

    1989-EY_Rodin-K_Egan-Mathematics modelling of the rate of chemical reactions
    The development of improved designs for chemical reactors as well as the prediction of optimal operating conditions in chemical production are based on an understanding of the rates at which chemical processes occur.
    kineticsfirst orderreactionsecond orderzeroth order
    Modeling Scenario
    176

    views

    495

    downloads

    0

    comments

    1-124-WorldPopulation-ModelingScenario
    We build models of world population using data to estimate growth rate.
    population dynamicshumangrowth ratevarying growth rate
    Modeling Scenario
    296

    views

    206

    downloads

    0

    comments

    1-026-Evaporation-ModelingScenario
    We provide data on evaporation of 91% isopropyl alcohol in six different Petri dishes and one conical funnel and on evaporation of water in one Petri dish. We ask students to develop a mathematical model for the rate of change in the respective...
    evaporationconealcoholPetri dish
    Modeling Scenario
    213

    views

    247

    downloads

    0

    comments

    1-114-EarthClimate-ModelingScenario
    In this modeling scenario, we investigate the Earth's climate using a zero-dimensional energy balance model. Energy balance models are climate models that try to predict the average surface temperature of the Earth.
    climateenergytemperaturelinearizationphase linesenergy balance modelroot finding
    Potential Scenario
    211

    views

    35

    downloads

    0

    comments

    2009-Das-EtAl-Bioeconomic harvesting of a pre-predator fishery
    This paper deals with the problem of non-selective harvesting of a prey–predator system by using a reasonable catch-rate function instead of usual catch-per-unit-effort hypothesis.
    predator-preyharvestingPontryagin’s maximum principlebioeconomicbionomic equilibriumbiotechnical productivitycatch-rate functionoptimal equilibrium
    Potential Scenario
    149

    views

    56

    downloads

    0

    comments

    2005-DieboldEtAl-Modeling Bond Yields In Finance And Macroeconomics
    From a macroeconomic perspective, the short-term interest rate is a policy instrument under the direct control of the central bank. From a finance perspective, long rates are risk-adjusted averages of expected future short rates.
    financeinterest ratebond yieldmacroeconomics
    Potential Scenario
    168

    views

    57

    downloads

    0

    comments

    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
    mathematical modeldataLSDMetabolismbloodstreamlysergic acid diethylamidedistribution
    Modeling Scenario
    310

    views

    258

    downloads

    0

    comments

    7-040-TankInterruptMixing-ModelingScenario
    We present a first order differential equation model for the interrupted mixing of a tank with salt water. We offer two solution strategies (1) two step approach and (2) Laplace Transforms.
    Laplace transforminverse Laplace Transformsalttankmixinginterrupt
    Modeling Scenario
    534

    views

    297

    downloads

    0

    comments

    5-011-ModelingIbuprofren-ModelingScenario
    We consider modeling of data from a clinical experiment administered as oral doses of 400 mg ibuprofen, an analgesic pain reliever. Concentrations of ibuprofen in the serum/plasma of the subjects were recorded after the initial ingestion of the...
    dataAICAkaike Information Criterionabsorptionsum of square errorscompartment modelibuprofendelay