Skip to Main Content
Powered by QUBES

Resources

Text Search:
Applied Filters
    Potential Scenario
    166

    views

    43

    downloads

    0

    comments

    2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
    This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
    concentrationphysiologydrugslag timeExtravascularPharamacokineticspeak time
    Potential Scenario
    118

    views

    41

    downloads

    0

    comments

    1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
    Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
    fishCell Membraneflowbloodbladdercountercurrent
    Modeling Scenario
    181

    views

    48

    downloads

    0

    comments

    1-131-CaffeineElimination-ModelingScenario
    We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    caffeineeliminationpharmacokineticsdrug
    Potential Scenario
    173

    views

    53

    downloads

    0

    comments

    2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
    The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
    anesthesiapharmacokineticspharmacodynamicanesthetic
    Modeling Scenario
    300

    views

    407

    downloads

    0

    comments

    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    nullclinespharmacokineticsdigoxindrug eliminationtwo compartment
    Potential Scenario
    243

    views

    57

    downloads

    0

    comments

    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Modeling Scenario
    257

    views

    156

    downloads

    0

    comments

    1-085-DrugBolus-ModelingScenario
    Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
    concentrationsum of square errorsbolusdrugrate constantadminister
    Modeling Scenario
    342

    views

    213

    downloads

    0

    comments

    1-097-SwimmingPool-ModelingScenario
    This project involves the dynamics of chlorine concentration during regular swimming pool maintenance cycles. Students will have the opportunity to use both analytic and numerical methods.
    concentrationcchlorinenumerical errorswimming poolhorineerreor
    Modeling Scenario
    874

    views

    1067

    downloads

    0

    comments

    3-061-ChemEngApps-ModelingScenario
    Students go through a chemical engineering problem: calculate concentration profile of cyclohexane within a catalyst pellet by solving a second order linear differential equation; then analyze the concentration as the radius of the catalyst...
    Spanishporous mediumcatalyisiscyclohexenehydrogeldehydrogenationhyperbolic trig functions
    Potential Scenario
    112

    views

    59

    downloads

    0

    comments

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticspharmacodynamicstherapeutic concentration rangedrug dispositiondrug response
    Modeling Scenario
    333

    views

    387

    downloads

    0

    comments

    1-011A-Kinetics-ModelingScenario
    We help students see the connection between college level chemistry course work and their differential equations coursework. We do this through modeling kinetics, or rates of chemical reaction.
    kineticsLaw of Mass Actionfittingorder of reactionchemical reaction
    Potential Scenario
    152

    views

    60

    downloads

    0

    comments

    1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
    Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We model this.
    LSDscoreplasmalysergic acid diethylamidehuman subjuects
    Modeling Scenario
    360

    views

    243

    downloads

    0

    comments

    1-138-InnerEarDrugDelivery-ModelingScenario
    Students examine local drug delivery to the cochlea. The delivery system is modeled as a liquid mixing problem. Students formulate the differential equation, and solve the equation using separation of variables or integrating factor.
    concentrationdrug deliveryinner earcochleahearing loss
    Potential Scenario
    113

    views

    44

    downloads

    0

    comments

    2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
    This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
    absorptioncompartmentbloodstreamplasmapharmacokineticsdrugpharmacodynamics
    Potential Scenario
    221

    views

    63

    downloads

    0

    comments

    2014-Blomhøj-EtAl-Compartment models
    An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
    concentrationkineticsphysiologycompartmentsalttankbalancereactionsminkbathtub
    Modeling Scenario
    235

    views

    281

    downloads

    0

    comments

    1-094-SteepingTea-ModelingScenario
    We provide photographs of steeping process for a tea steeped in hot water. Students build a differential equation model for the steeping process and do parameter estimation using the color of our tea as a way to measure relative concentration.
    concentrationSurface AreacolorNewton's Law of Coolingteasugar
    Modeling Scenario
    256

    views

    97

    downloads

    0

    comments

    5-030-AirshedSulphur-ModelingScenario
    Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for analysis to predict long-term levels of levels of...
    sulphurpollutionairshedhydrogen sulfidesulfur dioxide
    Potential Scenario
    124

    views

    50

    downloads

    0

    comments

    2004-Ledzewicz-Schattler-Application of Control Theory in Modelling Cancer Chemotherapy
    In this paper we discuss how to incorporate more realistic medical aspects of chemotherapy which hitherto have been neglected in the models.
    optimal controldrug resistancepharmacokineticspharmacodynamicschemotherapy
    Potential Scenario
    115

    views

    36

    downloads

    0

    comments

    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model
    Potential Scenario
    114

    views

    61

    downloads

    0

    comments

    2016-Erno_Keszei-Chemical Kinetics for Beginners
    The most important goal of kinetic research is the identification and characterisation of elementary molecular events which make possible the transformation of reactants into products.
    kineticszeroth order reactionfirst order reactionsecond order reactionreaction ratesthird order reaction