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Views
Date
Relevance
Potential Scenario
166
views
43
downloads
0
comments
2012-Jambhekar-Breen-Extravascular Routes Of Drug Administration in Basic Pharamacokinetics
This provides an excellent step-by-step of the physiology, construction of model, and notions like peak concentration as well as issues like lag time.
concentration
physiology
drugs
lag time
Extravascular
Pharamacokinetics
peak time
Potential Scenario
118
views
41
downloads
0
comments
1989-EY_Rodin-S_Jaques-Countercurrent Oxygen Exchange in the Swim Bladders of Deep-Sea Fish
Oxygen diffuses from lungs into blood, nutrients diffuse from intestinal tracts into blood and from blood into various cells, and waste products diffuse from cells back into blood.
fish
Cell Membrane
flow
blood
bladder
countercurrent
Modeling Scenario
181
views
48
downloads
0
comments
1-131-CaffeineElimination-ModelingScenario
We model the concentration of caffeine eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
caffeine
elimination
pharmacokinetics
drug
Potential Scenario
173
views
53
downloads
0
comments
2015-Valerie_Billard-Pharmacokinetic-pharmacodynamic relationship of anesthetic drugs - from modeling to clinical use
The purpose of this short review is to describe the basis of pharmacokinetics and modeling, the concentration-effects relationship, and drug interactions modeling to offer to anesthesiologists and non-anesthesiologists an overview of the rules to...
anesthesia
pharmacokinetics
pharmacodynamic
anesthetic
Modeling Scenario
300
views
407
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Potential Scenario
243
views
57
downloads
0
comments
1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
LSD
correlation coefficient
compartment model
lysergic acid diethylamide
performance
test score
tissue concentration
Modeling Scenario
257
views
156
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Modeling Scenario
342
views
213
downloads
0
comments
1-097-SwimmingPool-ModelingScenario
This project involves the dynamics of chlorine concentration during regular swimming pool maintenance cycles. Students will have the opportunity to use both analytic and numerical methods.
concentration
c
chlorine
numerical error
swimming pool
horine
erreor
Modeling Scenario
874
views
1067
downloads
0
comments
3-061-ChemEngApps-ModelingScenario
Students go through a chemical engineering problem: calculate concentration profile of cyclohexane within a catalyst pellet by solving a second order linear differential equation; then analyze the concentration as the radius of the catalyst...
Spanish
porous medium
catalyisis
cyclohexene
hydrogel
dehydrogenation
hyperbolic trig functions
Potential Scenario
112
views
59
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Modeling Scenario
333
views
387
downloads
0
comments
1-011A-Kinetics-ModelingScenario
We help students see the connection between college level chemistry course work and their differential equations coursework. We do this through modeling kinetics, or rates of chemical reaction.
kinetics
Law of Mass Action
fitting
order of reaction
chemical reaction
Potential Scenario
152
views
60
downloads
0
comments
1964-Aghajanian-Bing-Persistence Of LSD In Plasma In Human Subjects
Two micrograms per kilogram of LSD-25 was administered intravenously to five normal human subjects. The concentration of[ drug in plasma was determined serially over the subsequent 8 hours. We model this.
LSD
score
plasma
lysergic acid diethylamide
human subjuects
Modeling Scenario
360
views
243
downloads
0
comments
1-138-InnerEarDrugDelivery-ModelingScenario
Students examine local drug delivery to the cochlea. The delivery system is modeled as a liquid mixing problem. Students formulate the differential equation, and solve the equation using separation of variables or integrating factor.
concentration
drug delivery
inner ear
cochlea
hearing loss
Potential Scenario
113
views
44
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
221
views
63
downloads
0
comments
2014-Blomhøj-EtAl-Compartment models
An overview of compartment models with many rich illustrations and much attention to various numerical methods in solutions of the resulting differential equations using Matlab. Also included is a section on the limitations of compartment models.
concentration
kinetics
physiology
compartment
salt
tank
balance
reactions
mink
bathtub
Modeling Scenario
235
views
281
downloads
0
comments
1-094-SteepingTea-ModelingScenario
We provide photographs of steeping process for a tea steeped in hot water. Students build a differential equation model for the steeping process and do parameter estimation using the color of our tea as a way to measure relative concentration.
concentration
Surface Area
color
Newton's Law of Cooling
tea
sugar
Modeling Scenario
256
views
97
downloads
0
comments
5-030-AirshedSulphur-ModelingScenario
Temperature inversions and low wind speeds trap air pollutants in a mountain valley for a period of time. Gaseous sulfur compounds are a significant air pollution problem. We offer a model for analysis to predict long-term levels of levels of...
sulphur
pollution
airshed
hydrogen sulfide
sulfur dioxide
Potential Scenario
124
views
50
downloads
0
comments
2004-Ledzewicz-Schattler-Application of Control Theory in Modelling Cancer Chemotherapy
In this paper we discuss how to incorporate more realistic medical aspects of chemotherapy which hitherto have been neglected in the models.
optimal control
drug resistance
pharmacokinetics
pharmacodynamics
chemotherapy
Potential Scenario
115
views
36
downloads
0
comments
2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
liverworts
intraveneous
pharmacokinetics
ethanol
ethanol infustion
pharmacodynamic
tissue model
Potential Scenario
114
views
61
downloads
0
comments
2016-Erno_Keszei-Chemical Kinetics for Beginners
The most important goal of kinetic research is the identification and characterisation of elementary molecular events which make possible the transformation of reactants into products.
kinetics
zeroth order reaction
first order reaction
second order reaction
reaction rates
third order reaction
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