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Downloads
Views
Date
Relevance
Potential Scenario
116
views
46
downloads
0
comments
1975-Rodda-Sampson-Smith-The One-Compartment Open Model Parameter Estimation
A new estimation procedure is proposed for estimating the parameters of the simplest pharmacokinetic model, the one-compartment open model.
compartment model
pharmacokinetics
nonlinear estimation
one compartment model
Modeling Scenario
431
views
185
downloads
0
comments
5-012-LipoproteinModeling-ModelingScenario
Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
wildlife
low-density-lipoprotein
tracer
compartment model
cholesterol
blood plasma
body tissue
Modeling Scenario
272
views
133
downloads
0
comments
5-022-ColdPill-ModelingScenario
A model for the flow of a cold pill drug through the gastrointestinal compartment to the bloodstream compartment of a human subject is proposed. Students solve the system of differential equation model, use known parameter values, and plot solutions.
rates
medicine
drug discovery
compartment
cold pill
gastrointestinal
bloodstream
Modeling Scenario
1115
views
5306
downloads
0
comments
5-001-LSD-ModelingScenario
We describe the use of a two compartment model of a linear system of first order linear differential equations to model lysergic acid diethylamide (LSD) in the body. We provide the data from the literature.
LSD
Spanish
compartment
pharmacokinetics
lysergic acid diethylamide
Potential Scenario
152
views
63
downloads
0
comments
1971-Carl_Metzler-Usefulness Of Two Compartment Open Model In Pharmacokinetics
Compartment models are widely used in pharmaceutical research to quantitate the kinetics of absorption, distribution, metabolism and excretion of a drug. In this article two applications of the two compartment open model are discussed.
LSD
compartment
pharmacokinetics
Potential Scenario
111
views
44
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
drug
pharmacodynamics
Potential Scenario
109
views
59
downloads
0
comments
2017-ASHP-Intro to Pharmacokinetics and Pharmacodynamics
This is the introductory Lesson 1 in an online set of materials to introduce Pharmacokinetics and Pharmacodynamics.
absorption
compartment
bloodstream
plasma
pharmacokinetics
pharmacodynamics
therapeutic concentration range
drug disposition
drug response
Modeling Scenario
219
views
147
downloads
0
comments
1-086-MedicinalPill-ModelingScenario
Administration of a medicinal pill in single and multiple doses is modeled.
medicine
spillover
compartment
bloodstream
GIT-Track
Modeling Scenario
299
views
407
downloads
0
comments
1-132-DigoxinElimination-ModelingScenario
We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
nullclines
pharmacokinetics
digoxin
drug elimination
two compartment
Potential Scenario
115
views
43
downloads
0
comments
2019-Banuelos_Danet_Flores_Ramos-Epidemiological_Math_Model_Approach_To_Political_System_with_Three_Parties
A nonlinear compartmental model is derived to study the movement between classes of voters with the assumption of a constant population that is homogeneously mixed.
politics
parameters
voting
compartment model
epidemiological model
equilibria
three-party system
Modeling Scenario
280
views
394
downloads
0
comments
5-005-Dialysis-ModelingScenario
We design a compartment model of a kidney dialysis machine and compare 3 and 9 compartments for the machine as well as determine the effect of change in one of the parameters in the model on the effectiveness to deliver quality dialysis.
countercurrent multiplier
kidney
dialysis
concurrent
compartment
Potential Scenario
116
views
72
downloads
0
comments
2014-Hrydziuszko-EtAl-Mathematical Two-compartment Model of Human Cholesterol Transport
We develop a two-compartment mathematical model to investigate cholesterol transport in the circulatory system and its de novo synthesis in the liver.
metabolic syndrome
compartment
cholesterol
two-compartment model
cholesterol transport
Modeling Scenario
174
views
115
downloads
0
comments
1-134-LanguageDynamics-ModelingScenario
Students will be introduced to a mathematical model for language dynamics. Specifically, the model describes the change in the fraction of a population speaking one language over another.
language
compartment
phase lines
bifurcation
switching
Modeling Scenario
250
views
156
downloads
0
comments
1-085-DrugBolus-ModelingScenario
Given data on the concentration of a drug in the plasma of a human in mg/L at certain time intervals in hours can we determine the rate at which the drug leaves the plasma as well as the initial amount administered in a intravenous bolus of the drug?
concentration
sum of square errors
bolus
drug
rate constant
administer
Potential Scenario
238
views
55
downloads
0
comments
1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
LSD
correlation coefficient
compartment model
lysergic acid diethylamide
performance
test score
tissue concentration
Potential Scenario
97
views
34
downloads
0
comments
2005-P_Howard-Modeling with ODE
In these notes we consider three critical aspects in the theory of ordinary differential equations: developing models of physical phenomena, mathematically well-posed, solving ODE numerically .
Fluid Mechanics
compartment
populations
variational methods
Hamiltonian mechanics
Potential Scenario
133
views
56
downloads
0
comments
2014-Michael_Monagan-The Mortgage Payment Problem Approximating a Discrete Process with a Differential Equation
In this article and a subsequent article I will give two non-standard examples that I've found helpful. The one presented here is a first order linear system. Second order systems and non-linear systems.
compartment
heating
house
Modeling Scenario
179
views
191
downloads
0
comments
5-020-ParacetamolAbsorption-ModelingScenario
We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
paracetamol
analgesic
vegetarian
non-vegetarian
Modeling Scenario
261
views
327
downloads
0
comments
1-065-AlgalBlooms-ModelingScenario
This modeling scenario investigates the massive algal blooms that struck Lake Chapala, Mexico, starting in 1994.
direction fields
tool:dfield
algae
harmful algae blooms
population
compartment
Lake Chapala
Potential Scenario
90
views
37
downloads
0
comments
1994-S_S_Everingham-C_Peter_Rydell-Modeling the Demand for Cocaine
This is a report prepared for the Office of National Drug Control Policy of the United States Army by the Rand Corporation. The report contains lots of data and builds a two compartment difference equation model.
drugs
two compartment
cocaine
demand
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