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    Potential Scenario
    228

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    1968-Wagner-Aghajanian-Bing-Correlation of performance test scores with tissue concentration of lysergic acid diethylamide
    This paper offers a two compartment model of lysergic acid diethylamide (LSD) in volunteer students and through parameter estimation models the amount of LSD in the tissue after its initial administration through the plasma.
    LSDcorrelation coefficientcompartment modellysergic acid diethylamideperformancetest scoretissue concentration
    Modeling Scenario
    165

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    181

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    5-020-ParacetamolAbsorption-ModelingScenario
    We offer drug absorption data on paracetamol, an analgesic pain reliever, for two different sets of patients, vegetarian and non-vegetarian. Students build a two compartment model for plasma and non-plasma (tissue) compartments of human patients.
    paracetamolanalgesicvegetariannon-vegetarian
    Modeling Scenario
    417

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    173

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    5-012-LipoproteinModeling-ModelingScenario
    Data from a study on the amounts of low-density-lipoprotein (LDL), form of cholesterol, in blood plasma is presented. Students build, validate, and use a compartment model of the kinetic exchange of the LDL between body tissue and blood plasma.
    wildlifelow-density-lipoproteintracercompartment modelcholesterolblood plasmabody tissue
    Potential Scenario
    110

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    34

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    2006-Han-EtAl-Ordinary differential equation models for ethanol pharmacokinetic based on anatomy and physiology
    Physiologically-based pharmacokinetic (PBPK) models have been used to describe the distribution and elimination characteristics of intravenous ethanol administration.
    liverwortsintraveneouspharmacokineticsethanolethanol infustionpharmacodynamictissue model
    Potential Scenario
    110

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    46

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    2004-Jones-Song-Thomas-Controlling wound healing through debridement
    In this article, a system of differential equations that models slough/wound interaction is developed.
    bacteriawound healinghealingderidingisocline
    Potential Scenario
    118

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    54

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    2014-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis.
    metabolic syndromecompartment modelcholesterolhigh blood cholesterol
    Potential Scenario
    99

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    67

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    2015-Wrona-EtAl-Two-compartment model as a teaching tool for cholesterol homeostasis
    To investigate cholesterol transport in the circulatory system, we have previously developed a two-compartment mathematical model. Here, we show how this model can be used as a teaching tool for cholesterol homeostasis
    metabolic syndromecholesterolhigh blood cholesterolcholesterol homeostasis
    Potential Scenario
    171

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    57

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    1957-Axelrod_ Brady_Witkop_Evarts-The Distribution and Metabolism of Lysergic Acid Diethylamide
    The development of a specific and sensitive method for the estimation of LSD in biological materials has enabled us to study the tissue distribution, excretion, rate of biotransformation, and metabolism of the drug, as well as the subcellular...
    mathematical modeldataLSDMetabolismbloodstreamlysergic acid diethylamidedistribution
    Potential Scenario
    102

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    42

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    2019-Radulescu-Lundgren-A_pharmacokinetic_model_of_lead_absorption_and_calcium_competitive_dynamics
    We build and analyze a compartmental model of lead pharmacokinetics, focused specifically on addressing neurotoxicity.
    QUBES Leadership Teamparametersabsorptionbifurcationpharmacokineticscalciumcognitive decline
    Potential Scenario
    368

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    35

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    2000-Erdman-Morelock-A Study of Kinetics The Estimation and Simulation of Systems of First-Order Differential Equations
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    kineticsSAScompartmentpharmacokinetics
    Potential Scenario
    152

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    41

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    1996-D_Erdman-MM_Morelock-A Study of Kinetics
    This paper introduces new and old features of the SAS System for the estimation and simulation of systems of first-order differential equations with emphasis on examples in kinetics.
    simulationkineticsparameter estimationEnzymesubstratesavingscompartmentstomachbloodginseng
    Article or Presentation
    128

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    61

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    2015-European_Bioinformatics_Institute-Bio-Models-Database
    Bio Models Database is a repository of computational models of biological processes. Models described from literature are manually curated and enriched with cross-references. All models are provided in the Public Domain.
    biologydatabasebioinformaticsModelscomputational models
    Potential Scenario
    139

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    49

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    2003-Richard-Carson-Tracer kinetic modeling in PET
    The use of radiopharmaceuticals and the imaging of their biodistribution and kinetics with modern instrumentation are key components to successful developments in PET.
    Metabolismtomographyradiopharmaceuticalspositron emission
    Modeling Scenario
    282

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    390

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    1-132-DigoxinElimination-ModelingScenario
    We model the concentration of digoxin eliminated from the human body at a rate proportional to the concentration. This is a ``first-order reaction'' in the language of pharmacokinetics -- the study of how drugs move in the body.
    nullclinespharmacokineticsdigoxindrug eliminationtwo compartment
    Potential Scenario
    173

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    80

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    2001-Smith-Moore-The SIR Model for Spread of Disease
    A multiple part tour of SIR Models freely available with Maple, Mathematics, and MatLab support files at MAA site.
    epidemicSIR modelEuler's methodherd immunityHong Kong flu
    Potential Scenario
    130

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    35

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    2007-Hui_Luo-Population Modeling by Differential Equations
    A general model for the population of Tibetan antelope is constructed. The present model shows that the given data is reasonably logistic.
    population dynamicsextinctionlogisticTibetan antelope
    Potential Scenario
    192

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    72

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    2017-Xiang_Liu-Mathematical Studies of Optimal Economic Growth Model with Monetary
    In this paper, efforts will be made to study an extended Neoclassic economic growth model derived from Solow-Swan Model and Ramsey-Cass-Koopsman Model.
    Optimal Control TheoryJacobianSolow-Swan modelMonetary policyoptimal economic growth
    Potential Scenario
    172

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    67

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    2014-XM-Huang-Ordinary Differential Equation Model and its Application in the Prediction Control of Population
    In this paper, we study two kinds of ordinary differential equation models, i.e., Malthus model and Logistic model, and discuss their applications in the prediction control of population.
    population dynamicsLogistic modelMalthus ModelPopulation Prediction Control
    Potential Scenario
    100

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    37

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    2008-Yang-EtAl-Differential Equation Model of HIV Infection of CD T-Cells with Delay 
    Abstract: An epidemic model of HIV infection of CD4+ T-cells with cure rate and delay is studied. We include a baseline ODE version of the model, and a differential-delay model with a discrete time delay.
    virusT cellsHopf bifurcationendemic equilibrium
    Potential Scenario
    174

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    57

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    2006-Graves-Peckham-Pastor-2D differential equations model for mutualism
    We develop from basic principles a two-species differential equations model which exhibits mutualistic population interactions.
    population dynamicsLotka-Volterragrowth ratemutualismLichen