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    Colon Cancer: A Case of Genetic Bad Luck
    Case study developed for an introductory genetics class published in the National Center for Case Study Teaching in Science

    Keywords: bioinformaticsNCBINIBLSEBLASTPublished in National Center for Case Study Teaching in Sciencecolon cancerpedigreegenetic testingAPC

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    The Polar Bear of the Salt Marsh? Warming Tolerance Limits of Local Species
    National Center for Case Study Teaching in Science- In the adaptation exercise, students explore connections between saltmarsh sparrow declines and declining populations of local species that live...

    Keywords: Coastal wetlandsConnecticutmanagementnortheastsea-level risesalt marsh

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    BSL-4: Authorized Personnel Only
    National Center for Case Study Teaching in Science resource on the 2014 Ebola epidemic. This resource is also included in the NIBLSE Learning Resource Collection

    Keywords: infectious diseaseexperimental designbioinformaticsEbolaNIBLSECase It!PCRBLASTmultiple sequence alignmentPublished in National Center for Case Study Teaching in Sciencepolymerase chain reactionfebrile illnessvirusELISAenzyme linked immunosorbent assayfilovirusAfrica

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    Leaping Lemur Life History
    This interrupted case study is intended for use in lower-division biology or ecology courses to complement the SimUText (SimBio) Life History chapter. Students practice calculating life history...
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    A Curious Display
    Case study on genetically modified organisms provided in English and American Sign Language.

    Keywords: geneticscase studyagricultureBiotechnologyenvironmental scienceDNAUniversal Design for LearningGMOAmerican Sign Language

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    HITS: A Network to Create Inquiry-based Case Studies | BIOME 2022
    We created the NSF-funded High-throughput Discovery Science & Inquiry-based Case Studies for Today’s Students (HITS) Research Coordination Network to address this gap. HITS brings together...

    Keywords: case studiesHigh-throughput Discovery Science & Inquiry-based Case Studies for Today’s StudentsHigh-throughput (HT) approaches

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    Grassy Narrows and Muskrat Falls Dam: Hypothesis Testing and t-Tests
    Students are introduced to concepts of hypothesis testing using elementary hypothesis tests, t-tests, and p-values as they compare a given fish population for methylmercury levels (using real and...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccBiogeochemical cyclesInterpret graphsSolving Equations and InequalitiesConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculations

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    Modified Grassy Narrows and Muskrat Falls Dam: Hypothesis Testing and t-Tests
    Methylmercury contamination within fish populations is an important toxin that affect human, animal, and environmental health, serving as a carcinogen (cancer-causing agent) and endocrine-disruptor...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccEndocrine DisruptorsBiogeochemical cyclesInterpret graphsSolving Equations and InequalitiesConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculationsbiomagnification

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    The Stomata Lab. What the past can tell us about our future - using fossil and modern plants to model atmospheric carbon dioxide
    Students will develop a mathematical model of the relationship between atmospheric CO2 and the number of stomata on a leaf (Stomata Index). They will evaluate the model graphically, statistically,...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinaryclimate changeregressionEcology and EvolutionStomataNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical AnalysisSmithsonian

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    Environmental Pollution & Public Health (Project EDDIE) used in an introductory Environmental Challenges course
    Environmental health is a field of study within public health that is concerned with human-environment interactions, and specifically, how the environment influences public well-being. In this...

    Keywords: public healthProject EDDIEpollution

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Traditional Ecological Knowledge and Natural History
    In this module, students will explore Western Science and Traditional Ecological Knowledge and review a case study of how the TEK of the Inuit provided a way of knowing and understanding the...

    Keywords: Traditional ecological knowledgeUnderstanding ScienceBowhead Whale

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    Investigating the ecological value of migratory fishes on stream ecosystems in southern Appalachia
    Using the Ecological Society of America’s Four-Dimensional Ecology Education (4DEE) framework, students apply ecological concepts such as energy flow, nutrient cycling, migration, and climate...

    Keywords: Stream ecologynutrient cycling4DEE Frameworkfish migration

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    Climate Diagrams Mini-Case Study for Ecology
    This mini-case study provides undergraduate ecology students with experience in how to read climate diagrams and how to put them together. The activity includes a discussion of actual and potential...
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    Globally endangered sea turtles of the Palmyra Atoll National Wildlife Refuge: A Focus on Scientific Analysis
    Based on the sea turtle case, students will (1) work on a worksheet by analyzing existing survey data, (2) conduct a literature review of two relevant research, and (3) draft a proposal for a...

    Keywords: sea turtle conservationliterature reviewResearch methodsProposal writingPalmyra Atoll

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    Grassy Narrows and Muskrat Falls Dam: The Central Limit Theorem and a t-test
    Students are introduced to concepts of sampling distributions and hypothesis testing using a simulation applet, elementary hypothesis tests, t-tests, and p-values as they compare a given fish...

    Keywords: statisticsmathematicsbiostatisticsecologybiologygraphingp-valuest-testshypothesis testingin-class activityZoologymercury biogeochemistrybiostatistics - generalfish populationqbccBiogeochemical cyclesInterpret graphsSolving Equations and InequalitiesConcepts in StatisticsElementary Hypothesis TestingMethylmercurydamsBioaccumulationtraditional dietsmercurymercury poisoningnative peopleindigenous populationCanadahydroelectricexplaining statisticsusing statisticsMake probability calculations

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    Case Study: Genetic Variation and Speciation in the Black Tailed Rattlesnake complex (Crotalus molossus)
    It is important for biology students to understand how genetic variation is related to the formation of species in nature. This module is intended for students to obtain first hand experience with...

    Keywords: phylogeneticscase studySpeciationtree readingsystematicsTree thinkingPhylogeographydistance learninggenetic variation

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes...

    Keywords: Vision and Changeecologyintroductory biologyImmunologymicrobiologydietanimal behaviormicrobiomecore conceptscoyotesBraingut-brain axisImmunoReachcytokinedysbiosis

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    Quantifying and Visualizing Campus Tree Phenology
    This lesson, published on CourseSource, enables collaborative teams to collect, quantify, and analyze observable seasonal changes in nature.

    Keywords: ecologyBiodiversityphenologyplant biologyCourseSource

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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