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    Team microBIOME Fall 2020 - DIY microbiome analysis
    This is our final team report for this year's BIOME Institute 2020. Learn about what we got up to and what we're planning for Spring 2021. If you want more information on REMNet go...

    Keywords: microbiomeDNA SubwayDIYREMNet microbiomesNephele

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    Gelin’: Gel Electrophoresis Simulation
    Students will understand how DNA is separated into a fingerprint by using a chromatography activity to simulate gel electrophoresis.

    Keywords: DNAgel electrophoresisdna fingerprintchromatography

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    DNA Barcoding & Biodiversity databases
    This resource pairs DNA barcoding databases with Biodiversity databases. Students collect their insect specimens in the field and use BLAST and BOLD to identify their species. They then use...
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    EvolSeq
    An Excel worksheet that simulates the molecular evolution of DNA sequences.

    Keywords: molecular evolutionDNA

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    Split Decomp
    This Excel worksheet performs split decomposition on a set of four DNA sequences and their associated amino acid sequences. The user can type in the sequences or paste them in from a text file.

    Keywords: phylogenyDNA sequenceamino acid sequencesplit decomposition

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    Using computational molecular modeling software to demonstrate how DNA mutations cause phenotypes
    This lesson is a five-week series of laboratory activities designed to help students transition from applying lower order thinking skills to the central dogma to applying higher-order thinking skills.

    Keywords: bioinformaticsNIBLSEProtein StructureDNAmolecular modelinggenotypephenotypeCourseSourcecomputational modelingcentral dogmaplant leaf structure

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    Lesson III - Annotation
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson III introduces Annotation, or assigning meaning to all...

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Bacteria Transformation
    TeachEngineering resource in which students construct paper recombinant plasmids to simulate the methods genetic engineers use to create modified bacteria.

    Keywords: bacteriaengineeringGMOsbacterial transformationplasmids

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    Building creatures with the central dogma of biology
    Activity that demonstrates how nucleotide changes can affect phenotypes

    Keywords: amino acidsnucleotidesRNADNAgenotypephenotypecentral dogma

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    Microbiome Analysis with Oxford Nanopore 16S amplicon sequencing data
    The resource is a brief description of an analysis pipeline for microbiome analysis of Oxford Nanopore 16S amplicon sequence data. We tested the Kraken 2 and Krona pipeline from nanogalaxy with...

    Keywords: microbiome analysis toolNanopore

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    Databases: A Study of Influenza
    This lesson introduces the student to the Influenza Research Database. Students will select Influenza genome sequences to see how they are related. Students tests hypotheses about evolutionary...

    Keywords: Bioinformatics EducationBioinformatics and Genomicsmolecular evolutionInfluenza

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    Lesson V - Phylogenetics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson V is an introduction to Phylogenetics.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    In silico chromosome mapping: Idiograms
    This workbook allows the user to construct idiograms (haploid or diploid), map sequences onto them, depict chromosome structural mutations, and perform side-by-side comparative analyses of...

    Keywords: InheritancemutationschromosomesidiogramDrosophila melanogaster

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    A Curious Display
    Case study on genetically modified organisms provided in English and American Sign Language.

    Keywords: geneticscase studyagricultureBiotechnologyenvironmental scienceDNAUniversal Design for LearningGMOAmerican Sign Language

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    Hemoglobin bioinformatics
    This is an introduction to bioinformatics using hemoglobin as an example. The worksheets introduce students to resources to explore the DNA, RNA and polypeptide linear structure with a brief...

    Keywords: bioinformaticsHemoglobinBLASTsickle cell diseaseMolecular Case StudyClustal OmegaMolCaseNet

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    The Ames Test
    Introduction to the Ames Test, published as GSA Learning Resource

    Keywords: geneticsNIBLSEDNAames testassay

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    Origin and Diversity of Armor in Girdled Lizards
    The girdled lizards (Cordylidae) are a family of distinctively armored lizards endemic to Sub-Saharan Africa. Students examine lizards in this family to classify the lizards based on morphological...

    Keywords: Evolutionphylogenetic analysisHerpetologynatural history collections3D modelsVertebrate MorphologyCT scanoVertConvergent Evolution

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    Introduction to Genome Annotation
    This exercise is an adaptation of the Annotation Lesson by Rosenwald et al. It introduces the use of bioinformatics tools to extract information from genome databases. It is a basic lesson on...

    Keywords: microbiologyGenome annotationBioinformatics EducationBioinformatics and Genomics

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    One species, two species, red species, lead species? Phylogenetics and species concepts with Plethodon salamanders
    This lab introduces students to species concepts and basic computer-based tree-building methods using published nuclear and mitochondrial sequence data for Plethodon salamanders.

    Keywords: phylogenetic analysisTree thinkingsalamanderAudience level - Advanced UG

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