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    Sizes, Scales and Specialization: Using Relative Proportions and Scientific Notation to Highlight the Diversity of Cell Types
    This module explores how cell size and shape varies across cell types in the human body by having students calculate relative proportions of numbers in scientific notation.

    Keywords: ExponentsRatiosCellsqbccmanipulate equationsCellular and Molecular BiologyVisual Accommodationsconverting unitschanging scales

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    Enzyme Kinetics: How Quickly Can Acetylcholinesterase Break Up Your Thoughts?
    This module contains exercises designed to help upper-level cell biology students understand the common graphical methods used to evaluate enzyme activity and to see the impact of inhibitors on...

    Keywords: cell biologyQuantitative reasoninginterdisciplinarylinear modelsInterpreting GraphsNIQBC2. Data and GraphsC4. mathematical modelsnonlinear models

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    Cell Cycle and Mitosis
    This module introduces activities that allow students to walk through the cell cycle and mitotic cell division processes. As part of the activities, students learn about and apply knowledge of...

    Keywords: introductory biologyQuantitative reasoningInterdisciplinary STEMquantitative biologyinterdisciplinaryquantitative skillscell functioncell cyclemitosisCell DivisionMitotic Indexcalculating meanstumorNIQBC2. Data and GraphsC4. mathematical modelsC3. Statistical Analysisstandard errormitotic phaseinterphase

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    Learn Biological Sciences and Chemistry through cellular transport and concentration ( online and hands-on)
    Osmosis is a process by which by which solvent move from a region of lower solute concentration to region of higher solute concentration through a semi-permeable membrane. Cells utilize the process...

    Keywords: statisticsdata analysisbiologycell biologyconcentrationskillscellchemistryOsmosisSpectrophotometersolutionsolutesolvent

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    The Perfect Brew: An Activity Demonstrating Cell Counting and Hemocytometer Use
    In this activity, students will explore the use of a hemocytometer for counting cells, demonstrate the relationship between the grid seen in the microscope with volume of liquid in suspension and...

    Keywords: RatiosmicrobiologyqbccCellular and Molecular BiologyUnderstanding fractionsconverting unitschanging scalesmeasurements

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    Why are Cells Small? Surface Area to Volume Ratio
    This module explores surface area to volume ratios in a cube and sphere in relation to cell size.

    Keywords: introductory biologygraphingRatiosOpenStaxqbccmanipulate equationsCellular and Molecular BiologyUse elementary functionsCreate graphsInterpret graphsRates and ProportionsSolving Equations and Inequalitiesinterpret tables

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Introduction to Mathematical Modeling in Biotechnology, Cell Biology, and Physiology
    The course is a mathematical and computational exploration of five diverse areas of biology: human locomotion, gene sequence analysis, signal transduction pathways involved in cancer,...

    Keywords: mathematical modelingcoursehuman locomotionneuroanatomyneurophysiologysignal transductiongene sequence analysis

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    Polyploidapalooza: Exploring the diversity and evolution of polyploid plants and animals
    This series of modules explores the complex world of polyploidy, including species formation, cell division, evolution, conservation, and economic importance. We focus on polyploidy across the...

    Keywords: Evolutionconservationnatural historyCell DivisionhybridizationPolyploidygenome duplicationallopolyploidyautopolyploidy

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    Graphing bacterial growth rates: semi-log graphs v linear graphs
    In this activity, students will explore the concept of binary fission, generation time, and bacterial growth curves, with an emphasis on the log phase. Students will use semi-log graphs and linear...

    Keywords: graphingexponential growthMicrobiology Educationmicrobiologybacteriagrowth rateUndergraduate STEM educationCommunity College Educationqbccmanipulate equationsCellular and Molecular BiologyCreate graphsInterpret graphsbinary fissionsemi-log graphlinear graphgrowth curvecreating graphsExponential and Logarithmic Functions

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Uninhibited Growth of Cells
    In this activity, students will explore the concept of binary fission, generation time, and bacterial growth curves, with an emphasis on the log phase. Students will use semi-log graphs and linear...

    Keywords: graphingexponential growthMicrobiology Educationmicrobiologybacteriagrowth rateUndergraduate STEM educationCommunity College Educationqbccmanipulate equationsCellular and Molecular BiologyCreate graphsInterpret graphsbinary fissionsemi-log graphlinear graphgrowth curvecreating graphsExponential and Logarithmic Functions

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    Linear Regression (Excel) and Cellular Respiration for Biology, Chemistry and Mathematics
    Students typically find linear regression analysis of data sets in a biology classroom challenging. These activities could be used in a Biology, Chemistry, Mathematics, or Statistics course. The...

    Keywords: statisticsmathematicsdata analysisdatalinear regressionbiologyonlinegraphinglinear equationsQuantitative reasoningassessmentcollege algebracellstatistical analysisregressionOERAlgebrachemistryModelscorrelationSimple Linear RegressionMicrosoft Excellab activityexperimentCellular ProcessesATPqbccUsing Excelmanipulate equationsCellular and Molecular BiologyConcepts in Statisticsoxidationline of best fitexplaining statisticsusing statisticsCellular RespirationPredictionsRespirationgraphing in ExcelLinear CorrelationExothermic Reactioncreate scatter plotAdenosine Triphosphate (ATP)germinating peasPre-lab activityStudent activityHybridCollecting DataR-squareRegression ModelFunctionDependent VariablesIndependent VariablesLinear EquationLinear Equation in two variablescreate graphcreate equationcreate regressioncreate plotinterpret regressioninterpret data

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    Osmosis: Determination of the rate of osmosis and the isotonic concentration
    This module contains exercises designed to help students understand how solute concentrations affect the direction and rate of osmosis. Students are given different scenarios to predict the...

    Keywords: introductory biologyQuantitative reasoninginterdisciplinarycell functionOsmosisNIQBC2. Data and GraphsC4. mathematical modelsC6. Quantitative LanguageC1. NumeracyC5. Logic and Algorithms

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    Understanding COVID-19 Biology to Design a Vaccine
    This multi-part case study introduces the reader to the SARS-CoV-2 virus, replication, and treatment. Additional worksheets introduce students to bioinformatics tools of 3-D protein visualization...

    Keywords: BLASTprotein structure modelingmolecular visualization and analysisCOVID19PDB

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    Cancer Genetics and an Interview with a Deaf Biomedical Researcher
    In this lesson, learners will learn about cancer genetics and understand and interpret graphs showing quantitative trait locus (QTL) data, survivor curve data, and other genetics data. Then,...

    Keywords: graph interpretationfmnDeaf EducationBioGraphIrepresentation in STEMBioGraphI graph InterpretationDeaf representation in STEM

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes...

    Keywords: Vision and Changeecologyintroductory biologyImmunologymicrobiologydietanimal behaviormicrobiomecore conceptscoyotesBraingut-brain axisImmunoReachcytokinedysbiosis

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    Fitting Exponential and Logistic Growth Models to Bacterial Cell Count Data
    In this activity, students will model a noisy set of bacterial cell count data using both exponential and logistic growth models. For each model the students will plot the data (or a linear...

    Keywords: modelingdata analysislinear regressiongraphingExponentsoptimizationcalculusInterpreting GraphsFunctionsqbccCellular and Molecular BiologyChoosing modelsUnderstanding ratesConcepts in Statisticsmeasurementsmanipulating equationscreating graphsExponential and Logarithmic Functionsinterpreting tables

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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