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    Box-of-Lessons Review, Fall 2022 - YouTube
    This video described the working group activities for BIOME Institute 2022 - Fall working group

    Keywords: carbohydratesproteinsNucleic Acid Structurebiomolecular structurebiomolecular visualizationProtein Data Bankresources @ Molecular CaseNetBIOME 2022pilotinglipidsbiomolecules

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    Molecular Basis of Sickle Cell Disease
    This multi part case on hemoglobin structure as it relates to oxygen binding and sickle cell disease focuses on utilizing bioinformatics and molecular visualization tools to learn about the sickle...

    Keywords: Hemoglobinmolecular visualization and analysisintroductory bioinformaticssickle cell diseasePDBMolecular Case Studyoxygen bindingmyoglobinmolecular literacy3D protein structuresstructural representations

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    Maria vs Malaria
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria.

    Keywords: bioinformaticsmolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Dynamic Programming
    In bioinformatics, dynamic programming is mainly used to align nucleotide and amino acid sequences, and to predict RNA and protein folding from primary sequence data.

    Keywords: RNAamino acid sequenceSequence alignmentdynamic programmingprotein folding

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    Maria vs Malaria - AR Adaptation
    This case study focuses on a specific enzyme Lactate Dehydrogenase (LDH) in the malarial parasite as a target for treating malaria. Students will be able to view selected molecular views from the...

    Keywords: bioinformaticsAugmented RealityLarge class sizemolecular visualizationstructure-functionuniprotProtein Data BankMolecular Case StudyMolecular CaseNet

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    Build Multiomic and Visualization Skills in Bioscience Lecture
    This resource promotes inclusive learning by using all free platforms to extend the central dogma to an applied experience. Genomics is focused on with literature reviews that are performed to...

    Keywords: geneticsBiochemistryBiology and Biochemistry EduationProtein StructureBioinformatics and GenomicsFunctional GenomicstranscriptomicsproteomicsRNAseqClinical genomicsprotein structure modelingInclusive teaching3D protein structure /function analysisinclusive classrooms3D protein structuresinclusivegene

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    Effect of the Intestinal Protein Snakeskin on the Lifespan of Fruit Flies: A Kaplan-Meier Survival Analysissource Draft (1)
    In this activity, students perform the Kaplan-Meier survival analysis on raw data obtained from an experiment that explores the effect of overexpressing the Snakeskin (Ssk) protein on the lifespan...

    Keywords: graphingBiochemistryhypothesis testingcalculus and biologyapproximating areas under curvesqbccCellular and Molecular BiologyCreate graphsInterpret graphsSolving Equations and Inequalitiesinterpret tablesConcepts in Statisticsusing statisticschi-square analysissurvival analysis

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    Lesson V - Phylogenetics
    Genome Solver began as a way to teach undergraduate faculty some basic skills in bioinformatics; no coding or scripting is required. Lesson V is an introduction to Phylogenetics.

    Keywords: Bioinformatics EducationBioinformatics and Genomics

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    Geography and Embodied Perceptions: a pathway to reanimating rivers through lived experiences.
    In this lesson students embark upon a journey through the many ways we come to know a watershed, with foci on its physical geography and our embodied perceptions. This enables students to formulate...

    Keywords: PhilosophygeographyRiver Field Studies Networkperceptionwatershednature journalexperiencesensationhumanityplacehomeembodied perceptionsense of placeplace attachmenttransdisciplinaryqualitative methodscalable

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    Quantifying Bacterial Growth in the Guts and Hemolymph of Fruit Flies: Mathematical Modeling and Data Interpolation/Extrapolation
    In this activity, students will analyze raw data obtained from an experiment that explores the effect of overexpressing the Ssk protein in order to strengthen the intestinal barrier and prevent...

    Keywords: graphingexponential growthlinear modelsqbccinterpolationConcepts in Statistics and Precalculus Understanding exponential rates and linear slopesExtrapolation

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    Learn genomics and bioinformatics through scientific thinking, creation and analysis (virtual and hands-on)
    Nucleic acid are biological molecules composed of nitrogen-containing bases, phosphate groups, and sugar molecules. The complimentary chemical bonding results in formation of double stranded DNA....

    Keywords: data analysisbioinformaticsnucleotidesproteinsRNAgenomicsScientific communicationscientific writingDNAmodelling scientific thinkinggenescientific thinkingcreation

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    Protein Analysis
    This Excel workbook allows the analysis of sample or imported protein sequences. The model can analyze protein sequences up to 500 amino acids long.

    Keywords: Protein sequencehydrophobicity/hydrophilicity

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    What Shapes a River: Field Lesson
    This lesson introduces students to field methods and theoretical concepts regarding the factors that shape river environments and ecosystems. Introductory material is followed by instruction in...

    Keywords: substrateRiver Field Studies Network Fluvial GeomorphologyWolman Pebble CountBankful FlowSediment Transport.

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    Kinetics of a Highly Conserved Enzyme - Carbonic Anhydrase
    This module contains exercises designed to introduce students to graphical representation of biological data. Students will explore the fundamental principles of enzyme kinetics including...

    Keywords: Excelintroductory biologycell biologygraphingslopeQuantitative reasoningdata visualizationquantitative biologyinterdisciplaryquantitative skillscorrelationenzyme functionInterpreting GraphsMichaelis-Mentenenzyme kineticsEnzyme activityenzyme inhibitionLinear and nonlinear analysisNIQBC2. Data and GraphsC4. mathematical modelsenzyme-substrateNIQB Interdisciplinary Quantitative Reasoningcarbonic anhydrase

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Computational Biology using R
    This is an introductory level course on computational biology.

    Keywords: simulationmoduleRcourseprojectsolutions

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    Laboratory Math
    Explanations and demonstrations on how to use mathematical equations for various laboratory purposes, including those specific to SEA-PHAGES (such as phage titer calculations) and those that are...
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    Cystic Fibrosis Mechanism and Treatment
    This animation shows how mutations in an ion channel protein lead to the genetic disease cystic fibrosis. The animation also discusses how research on this protein has been used to develop...

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymacromoleculesGenetic diseaseCell Structure & Function

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    Intro videos and terminology for GMOs, Transcription, Translation
    Compiled resources around GMOs and protein production including vocabulary, animations, videos, and games

    Keywords: geneticsagricultureplantstranscriptiongenomesGMOtranslation

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    The p53 Gene and Cancer
    This tutorial describes the structure and function of the p53 protein, how its activity is regulated in cells, and how mutant versions of p53 can lead to cancer.

    Keywords: Resources @ HHMI - BioInteractiveBiochemistrymolecular biologymacromoleculesGenetic disease

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