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    Antigen presentation and cytotoxic T lymphocytes (CTLs): elucidating a common roadblock for students
    Active learning resource for pre-Nursing anatomy and physiology lecture explaining antigen presentation to CTLs and how the CTLs recognize and destroy the pathogen using Biointeractive animations...

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    Targeting Infected Cells for Immune Defense
    This animation shows how a cell infected by a virus signals cytotoxic T cells to destroy itself.

    Keywords: Resources @ HHMI - BioInteractiveimmune systemAnatomy & PhysiologyCell communication

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    CRISPR Gene Editing: Designing the gRNA and Donor Template
    In this adaptation, students learn how CRISPR/Cas9 is used in bacterial immunity and gene editing. Students create both a gRNA target and a donor template to edit a gene. Mutations can be from the...

    Keywords: geneticseducationcell biologymolecular biologymutationStem cellsstructure-functionmolecular visualization and analysis3D protein structure /function analysisCRISPR/Cas9crisprDNA mutationPiwiPDBMolecular Case StudyPiwi Matters

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    Immunity and Vaccine Action
    From the cellular level on up, being aware of your interactions can help you stay safe. This resource addresses fundamental immunology and infectious disease concepts through a historical...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

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    When tests disagree, how do I know if I have COVID-19?
    Students will learn about infectious disease and the immune response to infection by investigating different types of tests (PCR, antigen, and antibody tests) to detect the SARS-CoV-2 viral genetic...

    Keywords: geneticsVision and Changeintroductory biologyinfectious diseasemolecular biologycore competenciesRT-PCRviruscore conceptsnon-majors biologySARS-CoV-2antibodyAntigenImmunoReachmolecular DiagnosticsCOVID-19 transmission

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    Vaccine Development and Testing
    Scientists have the tools and knowledge to develop safe, effective vaccines, from trials to vials. This resource addresses the process by which vaccines are designed, tested and regulated. Key...

    Keywords: immunology educationvaccine literacyvaccine hesitancy

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    Using the IEDB to Predict Proteasomal Cleavage Events and T-cell Epitopes
    Research experiences provide a valuable view into the world of science and a great way to explore new fields and careers while developing critical thinking skills. The development and maintenance...

    Keywords: biologydatabaseImmunologydata sciencebioinformaticsBiotechnologyt-cellengineeringantibodyBioengineeringAntibody EngineeringlymphocytesProteinNetChopepitopeIEDBB-cellProteasomeProteasomal Cleavage

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    Let me in: Interpreting graphs of parasite infection in red blood cells
    The goal of this activity is to familiarize students with reading graphs, to think about how cells are different from one another and how parasites can take advantage of cell surface markers to...

    Keywords: graph interpretationfmnCellsStem cellsmalariaBioGraphIrepresentation in STEMcell sortinginfection efficiencycell surface proteinscell recongitionred blood cells

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    Electrical Activity of Neurons
    This tutorial describes how neurons generate action potentials, and how scientists measure neuronal activity and record the firing of individual neurons.

    Keywords: Resources @ HHMI - BioInteractiveAnatomy & PhysiologyNervous systemCell communication

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    Mark-Recapture
    A common method used to estimate the population size of a species is the Mark-Recapture method.

    Keywords: mark-recapture analysispopulation estimation

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    Transpiration
    In this lab, students will examine differences between C3 and C4 plants in their transpiration rates.

    Keywords: plant physiologybotanylaboratoryResource Type

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    Following the Data
    The video and exercise provides insight into how researchers are using digital data resources to investigate biodiversity in prairie fen wetlands.

    Keywords: data in the classroomprocess of sciencebiodiversity informatics

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    3D FractaL-Tree
    3D FractaL-Tree allows scientists to collect data from actual specimens in the field or laboratory, insert these measurements into a spatially explicit L-system package, and then visually compare...

    Keywords: fractalsL-systems

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    Navigating Bacterial Changes in Aging Organisms: Graphs, Patterns, and Models
    Aging is an incredibly important area of research, and recent biological advances implicate the intestines in aging pathologies. Given that the gut harbors an immense amount of an organism’s...

    Keywords: statisticsgraphingmathematics for life sciencesmathexponential growthPrecalculus

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    Bacteria to Brains in Backyard Coyotes: An Interdisciplinary Pedagogical Case Study
    Our interdisciplinary pedagogical case study explores the differences between rural and urban coyotes at the levels of organismal and community ecology. The focus is on how coyotes’ gut microbiomes...

    Keywords: Vision and Changeecologyintroductory biologyImmunologymicrobiologydietanimal behaviormicrobiomecore conceptscoyotesBraingut-brain axisImmunoReachcytokinedysbiosis

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    The Tentative Nature of Science
    This part focuses on the tentative nature of science

    Keywords: scienceCOVID19Tentative Nature

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    Venom Diversity & Evolution in Reptiles and Amphibians - An education module for university students
    This module contains information for a three part series introducing the venom system in reptiles and discussing it in an evolutionary context. In the first part venom and its ecological roles are...

    Keywords: geneticsEvolutionecologyHerpetologyAmphibans and ReptilesVenom

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    Developmental Allometry: Scaling in Growth
    This Excel workbook illustrates a number of allometric equations in animal growth. The workbook also calculates an allometric equation with graphical output for data entered by the user.

    Keywords: allometrybrain developmentSkeletal Systemmetabolic rate

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    Learn Biological Sciences and Chemistry through cellular transport and concentration ( online and hands-on)
    Osmosis is a process by which by which solvent move from a region of lower solute concentration to region of higher solute concentration through a semi-permeable membrane. Cells utilize the process...

    Keywords: statisticsdata analysisbiologycell biologyconcentrationskillscellchemistryOsmosisSpectrophotometersolutionsolutesolvent

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    The Power and Limits of Science
    This part focuses on the power and limits of science

    Keywords: powersciencelimitsCOVID19

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