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    1-141-MMGameRevisited-ModelingScenario
    It is assumed that the probability of an M&M chocolate, when tossed, falling on the M side is 0.5 The goal is to find a probability distribution of the probability q which is Pr(randomly chosen...

    Keywords: Probabilitystochastic processesBayesian methodsprobability distribution

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    BioBayes
    The BioBayes module leads the user through several different methodologies for applying Bayesian probabilities to real life examples and problems, such as HIV and cystic fibrosis screening.

    Keywords: pedigreesbayesian statisticsHIVTwo-Way Tablespunnett squarescystic fibrosis

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    Binomial test
    This lesson focused on introducing students to binomial data analysis and reinforcing concepts of confidence intervals, p-value interpretation, and one- vs two-sided tests.
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    2008-Huangi-Lu-Modeling long-term longitudinal HIV dynamics with applications to an AIDS clinical study 
    To better understand the factors responsible for the virological failure, this paper develops the mechanism-based nonlinear differential equation models for characterizing long-term viral dynamics...

    Keywords: longitudinal dataAIDSantiretroviral drug therapyBayesian nonlinear mixed-effectstime-varying drug efficacyHIV dynamics

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    2008-Lawson-Marion-An Introduction to Mathematical Modelling
    This is a broad based set of notes with sections: Building Models, Studying Models, and Using Models. No depth on any model, no solution strategies, but good references to models, and general...

    Keywords: time serieslinear regressionAkaike Information Criterionmcomparision models

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    Spreadsheet Tutorial 5: Histogram
    Generate a histogram using a variety of methods.

    Keywords: Resources @ HHMI - BioInteractiveScientific ProcessStatistics and MathScientific MethodologyHigh School

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    2015-Eric_Sullivan-Numerical Methods_An_Inquiry-Based_Approach_with_Python
    This is an OER effort on the part of Eric Sullivan to explore the joy of numerical methods. He has provided several versions.

    Keywords: pythonnumerical analysisNumerical Methods

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    2-001-NumericalMethodsComparisons-TechniqueNarrative
    This material teaches the basics of numerical methods for first order differential equations by following graphical and numerical approaches. We discuss the order of accuracy of the methods and...

    Keywords: Euler's methodimproved Euler's methodRK3 methodsRK4 methodsorder of accuracyabsolute errorCPU time

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    5-005-StiffDifferentialEquations-TechniqueNarrative
    This material introduces the topic of ``stiffness'' for a system of ordinary differential equations (ODE's), through a series of examples. Stiffness is a property that a system of ODE's may...

    Keywords: Euler's methodexplicit methodsimplicit methodsstiffsitffnessstiff differential equationinstability

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    1-060-RegularPerturbation-TechniqueNarrative
    This paper presents an introduction to a set of analytical approximations referred to as regular perturbation. This is a particular mathematical tool within the broader set of perturbation...

    Keywords: perturbationregular perturbationasymptotic expansionsanalytical approximationBernoulli equation

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    Building Trees: Introducing evolutionary concepts by exploring Crassulaceae phylogeny and biogeography
    Teaching evolutionary theory is foundational for all biological sciences and a key aspect of overall science literacy. The conceptual framework for understanding evolution relies on thinking...

    Keywords: EvolutionphylogeneticsTree thinkingbiogeography

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    BIO 439/539: Big Data Analysis
    Course materials for BIO 439/539: Big Data Analysis

    Keywords: Rdata analysisbig datadata managementstatistical methods

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    An Introduction to Statistical Learning: with Applications in R
    This book provides an introduction to statistical learning methods and is aimed for upper level undergraduate students, masters students and Ph.D. students in the non-mathematical sciences.

    Keywords: linear regressiontextbookclassificationcourseclustering coefficientR programming languagestatistical learningmachine learninglogistic regressionresamplingmodel selectionGeneralized additive modelsdecision treesprincipal components analysisMOOCResources @ QUBES - Teaching & Reference

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    2007-Zenker-Rubin-Clermont-From inverse problems in mathematical physiology to quantitative differential diagnoses
    The improved capacity to acquire quantitative data in a clinical setting has generally failed to improve outcomes in acutely ill patients, suggesting a need for advances in computer-supported data...

    Keywords: physiologyinverse problem

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    2015-Dan_Sloughte-Notes on Diffy Qs Differential Equations for Engineers
    This is a calculus book with the last chapter devoted to ordinary differential equations topics. The effort begins with a study of numerical methods and goes through traditional technique strategies.

    Keywords: Numerical Methodspendulumtext

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    2018-Robert_Phair-Differential_equation_methods_for_simulation_of_GFP_kinetics_in_non–steady_state_experiments
    Here, we derive new tracer kinetic analytical methods for non–steady state biological systems by constructing mechanistic nonlinear differential equation models of the underlying cell biological...

    Keywords: protein quality controlkineticsCellssteady statechemical kineticsfluouresencephotoactivationinytracellular

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    Tag You're It: A Lesson Investigating Study Design and Survival Analysis on an American Shad Tagging Study
    In this lesson, students will learn about the various mark-recapture and tagging methods that are used in various scientific disciplines and the information they can gather. Key elements of...

    Keywords: survival analysisAmerican ShadCox Proportional Hazards ModelStudy Design

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    Ground Spider Survey QUBES Resource Draft (1)
    This QUBES Module aims to introduce students to standardized ecological field methods, measures of diversity, ArcGIS Online, and Excel. This is achieved through nocturnal survey of ground spiders.

    Keywords: Community EcologyspidersMicrosoft ExcelShannon diversity index

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    2011-Carl_Leinbach-Beyond Newton's law of cooling - estimation of time since death
    The paper offers an excellent history of temperature-based methods and then proceeds to demonstrate these with some data. Here the history is rich and will support student investigation as well as...

    Keywords: time of deathNewton's aw of cooling

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    2005-Albert_Tarantola-Inverse Problem Theory and Methods for Model Parameter Estimation
    This is a bible of approaches to support parameter estimation approaches in inverse problems. Theory and algorithms are offers with examples.

    Keywords: Algorithminverse probleminverse

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