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The QUBES platform hosts hundreds of teaching materials, reference materials, and cloud-based software free to use and adapt using open Creative Commons licenses.

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    The Science and Ethics of Gene Drives: An Active Learning Lesson in Genetics
    Coursework connecting biology to socially relevant issues and ethical questions can help students think about biology in interdisciplinary terms. Gene drives represent one topic involving both...

    Keywords: bioethicsCRISPR/Cas9Genetic modificationGene drives

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    Analyzing Data on Behavioral and Immunological Effects of Inflammation in Mice
    In this activity, students will learn about behavioral and immunological responses to a bacterial infection. The activity emphasized the host’s responses rather than bacterial manipulation of the...

    Keywords: Vision and Changedata analysisImmunologybehaviorphysiologyinflammationinterdisciplinary educationAntigenmouseImmunoReachSicknessleukocyteneutrophilLipopolysaccharideacute phase response

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    A Journal Club Project to Promote Interpreting and Presenting Information From the Primary Scientific Literature
    Many undergraduate students receive little guidance on how to critically read, interpret data within, or present information from the primary scientific literature before they begin senior...

    Keywords: primary literaturejournal clubScience CommunicationfeedbackPeer reviewgroup workOral presentationProcess skillsPeer evaluationDevelopmental neurobiology

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    Glycolysis Can Be Fun: Rediscovering Glycolysis as a Problem-Solving Introduction to Metabolism
    A thorough understanding of glycolysis forms a foundation for students to analyze subsequent topics in metabolism, a core competency recognized by multiple national societies for biology and...

    Keywords: Problem based learningPOGILenzymesGlycolysisMetabolismFermentationchemical reactionsCard sorting activityCofactors

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    Serial Dilutions
    In this Excel workbook, users will enter the original cell concentration and the desired dilution factor (10, 100, and 1000). The program will then calculate the new cell concentration.

    Keywords: concentrationScientific Notationorders of magnitudeserial dilutions

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    Protein Analysis
    This Excel workbook allows the analysis of sample or imported protein sequences. The model can analyze protein sequences up to 500 amino acids long.

    Keywords: Protein sequencehydrophobicity/hydrophilicity

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    Hidden Markov Model
    Hidden Markov models are a set of mathematical tools that can be used to draw inferences about genomic and evolutionary processes.

    Keywords: hidden markov models

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    Evolution Through Natural Selection
    This Excel workbook simulates the population genetics of a single gene with two alleles, allowing the user to set the initial allele frequencies and enter parameters for a variety of different...

    Keywords: population geneticsNatural Selection

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    ESS: Evolutionary Stable Strategies Game Theory Module
    This Excel workbook illustrates a number of ESS examples. Each example allows the user to manipulate the initial population for each strategy and the fitness payoffs and costs for each strategy.

    Keywords: population geneticsfitnessgame theorySequence alignmentevolutionary stable strategies

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    Dynamic Programming
    In bioinformatics, dynamic programming is mainly used to align nucleotide and amino acid sequences, and to predict RNA and protein folding from primary sequence data.

    Keywords: RNAamino acid sequenceSequence alignmentdynamic programmingprotein folding

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    Deme 2.0
    This workbook simulates the population genetics of a single gene with two alleles. It can simultaneously model up to three local populations, which may differ in their selection coefficients.

    Keywords: population geneticsGenetic DriftNatural Selection

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    Continuous Growth Models
    This Excel worksheet compares user-input growth data with predictions under linear, exponential, and logistic models of growth. Introduces concepts of statistical analysis that can be additionally...

    Keywords: exponential growthlogistic growthcurve fittinglinear growthgrowth models

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    Buffer Preparation
    This Excel workbook calculates the necessary components to create a buffer solution using the Henderson-Hasselbalch equation.

    Keywords: buffer solutionacidbase

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    Biostatistical Tools
    This Excel collection of workbooks has tools for: 1. Linear regression through the origin 2. Linear regression not through the origin 3. Polynomial fit 4. A simple chi-square analysis to test...

    Keywords: linear regressionchi-square analysisHardy-Weinberg equilibriumpolynomial regression

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    Biological Cellular Automata Laboratory (BioCA Lab)
    This Excel module includes both linear cellular automata and 2D cellular automata. The original 3 rules for survival, death, and birth are implemented in this module, but users with some Excel...

    Keywords: cellular automata

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    BioGrapher
    BioGrapher is an Excel front-end for the AT&T GraphViz graphical visualization and layout package (http://www.graphviz.org/).

    Keywords: network theorygraph theoryphylogenetic trees

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    Untitled QUBES Resource Draft (1)
    Social Justice Dialogues in STEM 2 is a resource to help facilitate conversations around various social contexts within STEM classroom.

    Keywords: EquitySTEM educationUDLjustice

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    Birthday Problem and Class Phenotypic Probabilities
    An Excel workbook exploring two related applications, the Birthday Problem and Class Phenotypic Probabilities. Students enter their own phenotypes into the workbook.

    Keywords: phenotypic probabilityallelic frequency

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    Learning Communities as a Driver for Humanizing STEM: Cultivating Authentic Conversations about Anti-Racism in Introductory Biology Pedagogy using Duoethnography
    In this study we present a retrospective debrief of a learning community of college biology professors who were exploring how to define and implement racial equity-focused practices and content in...

    Keywords: Equitysocial justicediversity

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    Learn biotechnology, biophysics and business through scientific thinking and innovation
    Scientific, leadership and innovation skills are also an integral framework of the curriculum. All of them together or individually are important for enhancement of knowledge, critical thinking,...

    Keywords: educationbusinessBiotechnologybiophysicsleadershiprecombinant DNAgroup workcloninginnovationscientific thinkingplasmid

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